{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T07:40:13Z","timestamp":1778658013410,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[1999,11,1]],"date-time":"1999-11-01T00:00:00Z","timestamp":941414400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[1999,11]]},"abstract":"<jats:p>We studied six children (four girls and two boys) suffering from cryptogenic myoclonic absence seizures with early onset. The age at onset of the seizures ranged between 6 and 27.8 months (mean age \u00b1 SD: 18.5 \u00b1 12.4 months). The neurologic evaluation was normal in all patients at the first hospital admission. After the diagnosis, we followed up all children for at least 5 years. At the end of follow-up, two of these patients (a girl and a boy) showed severe mental retardation, a high number (from one to three per day) of seizures, and persistent pathologic electroencephalograms. The other patients showed normal electroencephalograms: all of them were seizure free and without mental retardation. The two patients with mental retardation have been treated with polytherapy. In all other children we used valproate alone successfully. Our data suggest that myoclonic absence seizures with early onset can have a good long-term prognosis. Valproate is a useful anticonvulsant drug in these patients. Mental retardation is present only in patients with poor seizure control. ( J Child NeuroL 1999;14:746-749).<\/jats:p>","DOI":"10.1177\/088307389901401112","type":"journal-article","created":{"date-parts":[[2008,1,24]],"date-time":"2008-01-24T19:24:33Z","timestamp":1201202673000},"page":"746-749","source":"Crossref","is-referenced-by-count":20,"title":["Epilepsy With Myoclonic Absences With Early Onset: A Follow-Up Study"],"prefix":"10.1177","volume":"14","author":[{"given":"Alberto","family":"Verrotti","sequence":"first","affiliation":[{"name":"Department of Medicine, Pediatrics Section University of Chieti"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rita","family":"Greco","sequence":"additional","affiliation":[{"name":"Department of Medicine, Pediatrics Section University of Chieti"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Chiarelli","sequence":"additional","affiliation":[{"name":"Department of Medicine, Pediatrics Section University of Chieti,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio","family":"Domizio","sequence":"additional","affiliation":[{"name":"Department of Medicine, Neonatology Section University of Chieti Chieti, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Sabatino","sequence":"additional","affiliation":[{"name":"Department of Medicine, Neonatology Section University of Chieti Chieti, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guido","family":"Morgese","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Siena Siena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1999,11,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.70.4.288"},{"issue":"3","key":"atypb2","first-page":"S42","volume":"34","author":"Porter RJ","year":"1993","journal-title":"Epilepsia"},{"key":"atypb3","unstructured":"Tassinari CA, Bureau M., Thomas P.: Epilepsy with myoclonic absences, in Roger J, Bureau M, Draver C, et al (eds): Epileptic Syndromes in Infancy, Childhood and Adolescence, 2nd ed. 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London , John Libbey, 1992, pp 89-96."},{"key":"atypb11","unstructured":"Loiseau P.: Childhood absence epilepsy, in Roger J, Bureau M, Draver C, et al (eds): Epileptic Syndromes in Infancy, Childhood and Adolescence , 2nd ed. London , John Libbey, 1992, pp 135-150."},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.1992.tb11445.x"},{"key":"atypb13","unstructured":"Roger J., Genton P., Bureau M., Dravet C.: Less common epileptic syndromes, in Wyllie E (ed): The Treatment of Epilepsy: Principles and Practice . Philadelphia, Lea & Febiger , 1993, pp 624-635."},{"key":"atypb14","unstructured":"Genton P., Dravet C.: Treatment of epilepsies with myoclonia, in Shorvon S, Dreifuss F, Fish D, Thomas D (eds): The Treatment of Epilepsy. 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