{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,14]],"date-time":"2026-06-14T13:10:33Z","timestamp":1781442633629,"version":"3.54.1"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2008,10,1]],"date-time":"2008-10-01T00:00:00Z","timestamp":1222819200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nut in Clin Prac"],"published-print":{"date-parts":[[2008,10]]},"abstract":"<jats:p>Heart failure (HF) is a major public health problem in the United States that puts a significant burden on both patients and the healthcare system. The prevalence of malnutrition in HF patients is well\u2010known and correlates with a dramatic decline in quality of life and disease progression, and is associated with high morbidity and mortality rates. The implication of HF on micronutrient status is underrecognized in the quest to offer \u201cbest practice\u201d medical, device, and surgical interventions to this population. The micronutrient thiamin is of particular interest in the management of HF for several reasons: (<jats:italic>a<\/jats:italic>) HF is a disease of the elderly whose micronutrient status is in need of attention; (<jats:italic>b<\/jats:italic>) HF patients tend to have inadequate nutrient intake, which has been associated with thiamin deficiency; (<jats:italic>c<\/jats:italic>) thiamin deficiency (wet beriberi) impairs cardiac performance and can mimic the signs and symptoms of HF thereby potentially exacerbating the underlying disease; (<jats:italic>d<\/jats:italic>) use of loop diuretics to manage fluid and sodium imbalances associated with HF may cause the hyperexcretion of thiamin, thereby increasing the risk of deficiency; and (<jats:italic>e<\/jats:italic>) the prevention of thiamin deficiency should be a routine component in the overall management of this disease.<\/jats:p>","DOI":"10.1177\/0884533608323430","type":"journal-article","created":{"date-parts":[[2008,10,10]],"date-time":"2008-10-10T17:32:39Z","timestamp":1223659959000},"page":"487-493","source":"Crossref","is-referenced-by-count":52,"title":["Characteristics of Thiamin and Its Relevance to the Management of Heart Failure"],"prefix":"10.1002","volume":"23","author":[{"given":"Jennifer A.","family":"Wooley","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,10]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"Heart Disease and Stroke Statistics: 2005 Update","author":"American Heart Association","year":"2005"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.07.012"},{"key":"e_1_2_6_4_1","first-page":"S107","article-title":"Economic impact of heart failure in the United States: time for a different approach","volume":"13","author":"O'Connell JB","year":"1994","journal-title":"J Heart Lung Transplant"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(97)70173-X"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi442"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(91)90007-K"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8223(95)00148-4"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.08.060"},{"key":"e_1_2_6_10_1","first-page":"184","article-title":"Thiamine deficiency in congestive heart failure patients receiving long term furosemide therapy","volume":"10","author":"Zenuk C","year":"2003","journal-title":"Can J Clin Pharmacol"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1527-5299.2007.06260.x"},{"key":"e_1_2_6_12_1","unstructured":"HardenD.Vitamin B1. 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