{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:27:56Z","timestamp":1761006476367,"version":"build-2065373602"},"reference-count":9,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,4,20]],"date-time":"2015-04-20T00:00:00Z","timestamp":1429488000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2015,4,20]],"date-time":"2015-04-20T00:00:00Z","timestamp":1429488000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Nut in Clin Prac"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:p><jats:italic>Background:<\/jats:italic> Drug shortages pose prescribing problems to clinicians. During fiscal year (FY) 2014, an acute shortage of intravenous potassium phosphate (K\u2010Phos IV), a common supplement in parenteral nutrition (PN), prompted the use of premixed instead of individualized PN to conserve K\u2010Phos IV. Here we quantify the K\u2010Phos IV conserved by using premixed PN and the associated cost differences. <jats:italic>Materials and Methods:<\/jats:italic> Costs of preparing premixed PN vs individualized PN of equivalent composition were calculated for FY 2014 at a single\u2010center tertiary care facility. Quantity and cost of K\u2010Phos IV saved were calculated based on the number of premixed PN prescriptions. Costs for FY 2015 were projected based on drug costs from July 2014. <jats:italic>Results:<\/jats:italic> During FY 2014, prescribing premixed in lieu of individualized PN conserved 16,440 mmol K\u2010Phos IV but increased the cost of PN by $4080.45. However, increases in K\u2010Phos IV cost at the end of FY 2014 resulted in premixed PN as a relatively less expensive therapy than individualized PN for our institution. Cost savings of $7092.20 due to use of premixed PN is projected for FY 2015. <jats:italic>Conclusions:<\/jats:italic> Prescribing premixed PN conserves K\u2010Phos IV during shortages, but it increased direct drug spending in non\u2013critically ill patients at our institution during FY 2014. Persistent shortages can drive market costs of K\u2010Phos IV, however, necessitating frequent reconsideration of resource utilization.<\/jats:p>","DOI":"10.1177\/0884533615583093","type":"journal-article","created":{"date-parts":[[2015,4,20]],"date-time":"2015-04-20T22:02:03Z","timestamp":1429567323000},"page":"218-222","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Use of Premixed Parenteral Nutrition During a Phosphate Shortage in a Non\u2013Critically Ill Population"],"prefix":"10.1002","volume":"31","author":[{"given":"Caitlin S.","family":"Curtis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca A.","family":"Busch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan L.","family":"Crass","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aaron P.","family":"Webb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth A.","family":"Kudsk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,4,20]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/phar.1350"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607111412382"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607113518583"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.2146\/ajhp110210"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607111434777"},{"key":"e_1_2_5_7_1","unstructured":"Drug shortages: national survey reveals high level of frustration low level of safety.ISMP Medication Safety Alert!2014;15:1\u20134.http:\/\/www.ismp.org\/newsletters\/acutecare\/articles\/20100923.asp. Accessed December 10 2014."},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607114550317"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607113509282"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.2146\/ajhp120733"}],"container-title":["Nutrition in Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0884533615583093","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0884533615583093","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aspenjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/0884533615583093","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T08:59:30Z","timestamp":1760950770000},"score":1,"resource":{"primary":{"URL":"https:\/\/aspenjournals.onlinelibrary.wiley.com\/doi\/10.1177\/0884533615583093"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,20]]},"references-count":9,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,4]]}},"alternative-id":["10.1177\/0884533615583093"],"URL":"https:\/\/doi.org\/10.1177\/0884533615583093","archive":["Portico"],"relation":{},"ISSN":["0884-5336","1941-2452"],"issn-type":[{"type":"print","value":"0884-5336"},{"type":"electronic","value":"1941-2452"}],"subject":[],"published":{"date-parts":[[2015,4,20]]}}}