{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T09:00:18Z","timestamp":1781168418564,"version":"3.54.1"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,8,4]],"date-time":"2016-08-04T00:00:00Z","timestamp":1470268800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2016,8,4]],"date-time":"2016-08-04T00:00:00Z","timestamp":1470268800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Nut in Clin Prac"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:p>Pellagra usually results from niacin deficiency and presents with the classic triad of dermatitis, diarrhea, and dementia. It is most commonly associated with malnutrition and poverty and is extremely rare in industrialized societies. Furthermore, pellagra can be induced by special clinical conditions that interfere with the intake, absorption, and metabolism of niacin. Because of its detrimental effects on health and its favorable prognosis after supplementation of nicotinamide, the importance of early diagnosis and treatment should be emphasized. Herein, we report a case of pellagra in a young alcoholic who underwent combined chemotherapy for tuberculosis. For the first time, a descriptive review of literature from 1957 to 2014 has been conducted to clarify potential etiologies of pellagra: alcoholism (35.24%, 37 articles), various medications (25.71%, 27 articles), inadequate oral intake (16.19%, 17 articles), malabsorption (13.33%, 14 articles), metabolic derangement (7.62%, 8 articles), excessive loss (0.95%, 1 article), and etiology unknown (0.95%, 1 article).<\/jats:p>","DOI":"10.1177\/0884533616660991","type":"journal-article","created":{"date-parts":[[2016,8,4]],"date-time":"2016-08-04T23:33:27Z","timestamp":1470353607000},"page":"785-789","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":35,"title":["Pellagra Secondary to Medication and Alcoholism"],"prefix":"10.1002","volume":"31","author":[{"given":"Rongrong","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kang","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangfeng","family":"Mao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaming","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,8,4]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022172400043205"},{"key":"e_1_2_3_3_1","first-page":"101","article-title":"Pellagra in California","volume":"8","author":"Blue R","year":"1910","journal-title":"Cal State J Med"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1940-0640-7-12"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2004.01959.x"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/alcalc\/agu010"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.5114\/pdia.2014.40969"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/15569527.2011.574303"},{"key":"e_1_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2230.1999.00444.x"},{"key":"e_1_2_3_10_1","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1176\/ajp.156.4.660","article-title":"Isoniazid\u2010induced pellagra and the N\u2010acetyltransferase gene genotype","volume":"156","author":"Muratake T","year":"1999","journal-title":"Am J Psychiatry"},{"key":"e_1_2_3_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.48.7.628"},{"key":"e_1_2_3_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.283.6286.287"},{"key":"e_1_2_3_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(79)92519-4"},{"key":"e_1_2_3_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1977.01640070120035"},{"key":"e_1_2_3_15_1","first-page":"716","article-title":"A case of pellagra induced by isoniazid therapy","volume":"218","author":"Harrington CI","year":"1977","journal-title":"Practitioner"},{"key":"e_1_2_3_16_1","first-page":"313","article-title":"Isoniazid\u2010induced pellagra","volume":"69","author":"Griffiths WA","year":"1976","journal-title":"Proc R Soc Med"},{"key":"e_1_2_3_17_1","first-page":"38","article-title":"Niacin deficiency in tuberculous patients treated with isoniazid","volume":"22","author":"Goldner B","year":"1970","journal-title":"Plucne Bolesti Tuberk"},{"key":"e_1_2_3_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1983.tb02114.x"},{"key":"e_1_2_3_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2008.02883.x"},{"key":"e_1_2_3_20_1","article-title":"A rare case of alcoholic pellagra encephalopathy with startle myoclonus and marked response to niacin therapy: time for a new dictum?","volume":"22","author":"Sharma B","year":"2013","journal-title":"BMJ Case Rep"},{"key":"e_1_2_3_21_1","doi-asserted-by":"publisher","DOI":"10.1258\/td.2012.120253"},{"key":"e_1_2_3_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2010.07.150"},{"key":"e_1_2_3_23_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0365-05962011000600021"},{"key":"e_1_2_3_24_1","first-page":"1880","article-title":"Pellagra (deficiency of vitamin B3 or of the amino acid tryptophan): a disease still extant in the Netherlands","volume":"2","author":"Pasmans SG","year":"1998","journal-title":"Ned Tijdschr Geneeskd"},{"key":"e_1_2_3_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.alcalc.a008400"},{"key":"e_1_2_3_26_1","doi-asserted-by":"publisher","DOI":"10.3109\/15569527.2013.800546"}],"container-title":["Nutrition in Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0884533616660991","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0884533616660991","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aspenjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/0884533616660991","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T08:57:39Z","timestamp":1760950659000},"score":1,"resource":{"primary":{"URL":"https:\/\/aspenjournals.onlinelibrary.wiley.com\/doi\/10.1177\/0884533616660991"}},"subtitle":["A Case Report and Review of the Literature"],"short-title":[],"issued":{"date-parts":[[2016,8,4]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["10.1177\/0884533616660991"],"URL":"https:\/\/doi.org\/10.1177\/0884533616660991","archive":["Portico"],"relation":{},"ISSN":["0884-5336","1941-2452"],"issn-type":[{"value":"0884-5336","type":"print"},{"value":"1941-2452","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,4]]}}}