{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:14:44Z","timestamp":1777853684630,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2003,9,1]],"date-time":"2003-09-01T00:00:00Z","timestamp":1062374400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Intensive Care Med"],"published-print":{"date-parts":[[2003,9]]},"abstract":"<jats:p>The authors retrospectively review their experience with low immunoglobulin G (IgG) levels in a pediatric ICU population over a 12-month period. The total IgG level was below the normal for age in 14 of the 20 patients. The 14 patients with a low IgG level were younger and weighed less when compared with the 6 patients who had a normal IgG level. There was no difference in the risk of mortality between the 2 groups. In the 14 patients with an IgG level less than normal for age, the IgG level was 33% to 99% of normal, with 4 patients having a level less than 50% of normal for their age. Prospective trials are needed to determine the incidence of this problem, its impact on survival, and the appropriate therapy in the pediatric ICU population.<\/jats:p>","DOI":"10.1177\/0885066603255905","type":"journal-article","created":{"date-parts":[[2003,9,20]],"date-time":"2003-09-20T04:25:16Z","timestamp":1064031916000},"page":"261-264","source":"Crossref","is-referenced-by-count":6,"title":["Hypogammaglobulinemia in Pediatric ICU Patients"],"prefix":"10.1177","volume":"18","author":[{"given":"Saif","family":"Rehman","sequence":"first","affiliation":[{"name":"Departments of Child Health and Anesthesiology, Division of Pediatric Critical Care\/Pediatric Anesthesiology, University of Missouri, Columbia, Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Bytnar","sequence":"additional","affiliation":[{"name":"Departments of Child Health and Anesthesiology, Division of Pediatric Critical Care\/Pediatric Anesthesiology, University of Missouri, Columbia, Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John W.","family":"Berkenbosch","sequence":"additional","affiliation":[{"name":"Departments of Child Health and Anesthesiology, Division of Pediatric Critical Care\/Pediatric Anesthesiology, University of Missouri, Columbia, Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph D.","family":"Tobias","sequence":"additional","affiliation":[{"name":"Departments of Child Health and Anesthesiology, Division of Pediatric Critical Care\/Pediatric Anesthesiology, University of Missouri, Columbia, Missouri,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2003,9,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-0704(18)30198-2"},{"key":"atypb2","unstructured":"2. 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