{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:15:07Z","timestamp":1777853707299,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2016,6,14]],"date-time":"2016-06-14T00:00:00Z","timestamp":1465862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Intensive Care Med"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Advances in extracorporeal membrane oxygenation (ECMO) have enabled rapid deployment in a wide range of clinical settings. We report our experience with venoarterial (VA) ECMO in adult patients over 10 years and aim to identify predictors of mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>This is a retrospective analysis of all adult patients undergoing VA ECMO at a tertiary care center from January 1, 2004, to December 31, 2013.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 224 consecutive cases were reviewed. Eighty (35.7%) patients survived to discharge and 144 (64.3%) patients died. Patients requiring ECMO for heart transplant graft failure had lower mortality (51.6%) compared to all other etiologies (69.1%; P = .02). Forty-two percent (94 of the 224) of the patients required cardiopulmonary resuscitation (CPR) preceding ECMO and had higher rate of in-hospital mortality (74.5%) compared with patients without cardiac arrest (56.9%; P = .01). Patients with less than 30 minutes of CPR had a mortality rate of 40.0% compared to 91.4% for CPR &gt; 30 minutes ( P = .001). In all, 24.1% of patients (54 of the 224) experienced ECMO-associated complications without significant increase in mortality, and 22.3% (50 of the 224) of the patients were transitioned to ventricular assist devices (VADs) or transplant. Patients bridged to a VAD including left ventricular assist devices and biventricular assist devices had a mortality rate of 56.1% versus 22.2% when bridged directly to transplant ( P = .01). Paradoxically, patients with an ejection fraction (EF) &gt; 35% had a higher mortality compared to patients with an EF &lt; 35% (75.3% vs 49.4%, respectively, P = .001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Extracorporeal membrane oxygenation in patients with heart transplant graft failure had the best outcome. In patients who had cardiac arrest, prolonged CPR &gt; 30 minutes was associated with very high mortality. Paradoxically, patients with EF &gt; 35% had a higher mortality than patients with EF &lt; 35%, likely reflecting patients with diastolic heart failure or noncardiac causes necessitating ECMO. For transplant candidates, direct bridge from ECMO to transplant could achieve a very good outcome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0885066616654451","type":"journal-article","created":{"date-parts":[[2016,6,15]],"date-time":"2016-06-15T08:37:50Z","timestamp":1465979870000},"page":"288-295","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":21,"title":["Temporary Venoarterial Extracorporeal Membrane Oxygenation: Ten-Year Experience at a Cardiac Transplant Center"],"prefix":"10.1177","volume":"33","author":[{"given":"Bao G.","family":"Tran","sequence":"first","affiliation":[{"name":"Department of Cardiology, University of California, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kim","family":"De La Cruz","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of California, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stuart","family":"Grant","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of California, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Meltzer","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, University of California, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peyman","family":"Benharash","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of California, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ravi","family":"Dave","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University of California, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abbas","family":"Ardehali","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of California, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Shemin","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of California, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eugene","family":"Depasquale","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University of California, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Nsair","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University of California, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,6,14]]},"reference":[{"key":"bibr1-0885066616654451","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197203232861204"},{"key":"bibr2-0885066616654451","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(00)02504-2"},{"key":"bibr3-0885066616654451","doi-asserted-by":"publisher","DOI":"10.1097\/MCC.0000000000000098"},{"key":"bibr4-0885066616654451","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0b013e3182904a52"},{"key":"bibr5-0885066616654451","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0b013e3181bad907"},{"key":"bibr6-0885066616654451","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199908263410901"},{"key":"bibr7-0885066616654451","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)61783-3"},{"key":"bibr8-0885066616654451","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181e8acf7"},{"key":"bibr9-0885066616654451","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezt207"},{"key":"bibr10-0885066616654451","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2012.01.037"},{"key":"bibr11-0885066616654451","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrtlng.2015.03.005"},{"key":"bibr12-0885066616654451","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/364236"},{"key":"bibr13-0885066616654451","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(03)01329-8"},{"key":"bibr14-0885066616654451","doi-asserted-by":"crossref","unstructured":"Doll N, Fabricius A, Borger MA, Temporary extracorporeal membrane oxygenation in patients with refractory postoperative cardiogenic shock\u2014a single center experience. 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