{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:13:36Z","timestamp":1777853616491,"version":"3.51.4"},"reference-count":32,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2018,2,8]],"date-time":"2018-02-08T00:00:00Z","timestamp":1518048000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Intensive Care Med"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Acute coronary syndrome is frequently complicated by rhythm disturbances, yet any association between high-density lipoprotein (HDL) cholesterol levels and arrhythmias in the setting of non-ST-segment elevation myocardial infarction (non-STEMI) is uncertain. The goal of this study was to evaluate any association between HDL-cholesterol levels and arrhythmias in the setting of non-STEMI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Retrospective data from Phoenix Veterans Affair Medical Center records were utilized for our study. A total of 6881 patients were found who presented during 2000 to 2003 with non-STEMI with available fasting lipid panels collected within the first 24 hours of admission. Patients were followed for the development of rhythm disturbances up to 6 years after initial presentation, with a mean follow up of 1269 days.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>We found that high triglycerides\/HDL and low-density lipid\/HDL ratios were predictive of arrhythmias. However, low HDL levels had strongest association with highest odds ratio (OR) for development of arrhythmias (for HDL &lt;31 mg\/dL, OR = 3.72, 95% confidence interval [CI] = 2.55-5.44, P &lt; .05) in patients with diabetes and (for HDL &lt; 31 mg\/dL, OR = 3.69, 95% CI = 2.85-4.71, P &lt; .05) in patients without diabetes. Using multivariate analysis adjusting for comorbidities, low HDL level remained independently associated with arrhythmias.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Patients with low HDL levels during hospitalization with non-STEMI have a greater risk of developing cardiac rhythm disturbances independent of other risk factors. These data suggest a possible protective role of HDL in preventing arrhythmias in the setting of acute coronary syndrome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0885066618756265","type":"journal-article","created":{"date-parts":[[2018,2,8]],"date-time":"2018-02-08T22:07:04Z","timestamp":1518127624000},"page":"438-444","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["High-Density Lipoprotein Cholesterol (HDL-C) Levels Independently Correlates With Cardiac Arrhythmias and Atrial Fibrillation"],"prefix":"10.1177","volume":"35","author":[{"given":"Farzin Brian","family":"Boudi","sequence":"first","affiliation":[{"name":"Phoenix Veterans Administration Health Care System, Phoenix, AZ, USA"},{"name":"University of Arizona College of Medicine, Phoenix, AZ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas","family":"Kalayeh","sequence":"additional","affiliation":[{"name":"VA Southern Nevada Healthcare System, North Las Vegas, NV, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Reza","family":"Movahed","sequence":"additional","affiliation":[{"name":"CareMore HealthCare, Tucson, AZ, USA"},{"name":"University of Arizona College of Medicine, Tucson, AZ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,2,8]]},"reference":[{"key":"bibr1-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.97.18.1837"},{"key":"bibr2-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.11.072"},{"key":"bibr3-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9150(99)00065-9"},{"key":"bibr4-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1016\/S1050-1738(01)00111-6"},{"key":"bibr5-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(02)02635-8"},{"key":"bibr6-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2012.01.029"},{"key":"bibr7-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(77)90874-9"},{"issue":"4","key":"bibr8-0885066618756265","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1590\/S1807-59322008000400003","volume":"63","author":"Da Luz PL","year":"2008","journal-title":"Clinics (Sao Paulo)"},{"key":"bibr9-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.114.001211"},{"key":"bibr10-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-11-0780"},{"key":"bibr11-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacl.2010.08.005"},{"key":"bibr12-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.538108"},{"key":"bibr13-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000183735.09871.61"},{"key":"bibr14-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2006.083923"},{"key":"bibr15-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1159\/000006942"},{"key":"bibr16-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1038\/nm1102-1211"},{"key":"bibr17-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.52.5.543"},{"key":"bibr18-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.59.4.416"},{"key":"bibr19-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(92)91767-K"},{"key":"bibr20-0885066618756265","first-page":"A31","volume":"19","author":"Tall AR","year":"1998","journal-title":"Eur Heart J"},{"key":"bibr21-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1097\/00041433-200406000-00006"},{"key":"bibr22-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.111.262477"},{"key":"bibr23-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2006.04.026"},{"key":"bibr24-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(01)01603-4"},{"key":"bibr25-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1002\/clc.20669"},{"key":"bibr26-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.11.070"},{"key":"bibr27-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b92"},{"key":"bibr28-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199908053410604"},{"key":"bibr29-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.103.23.2828"},{"key":"bibr30-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1001\/jama.285.12.1585"},{"key":"bibr31-0885066618756265","doi-asserted-by":"publisher","DOI":"10.25011\/cim.v39i6.27489"},{"key":"bibr32-0885066618756265","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelectrocard.2016.03.013"}],"container-title":["Journal of Intensive Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0885066618756265","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0885066618756265","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0885066618756265","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:55:06Z","timestamp":1777503306000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0885066618756265"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,8]]},"references-count":32,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["10.1177\/0885066618756265"],"URL":"https:\/\/doi.org\/10.1177\/0885066618756265","relation":{},"ISSN":["0885-0666","1525-1489"],"issn-type":[{"value":"0885-0666","type":"print"},{"value":"1525-1489","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2,8]]}}}