{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:15:15Z","timestamp":1777853715464,"version":"3.51.4"},"reference-count":64,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2019,9,5]],"date-time":"2019-09-05T00:00:00Z","timestamp":1567641600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Intensive Care Med"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:p>Resuscitation after out-of-hospital cardiac arrest can be one of the most challenging scenarios in acute-care medicine. The devastating effects of postcardiac arrest syndrome carry a substantial morbidity and mortality that persist long after return of spontaneous circulation. Management of these patients requires the clinician to simultaneously address multiple emergent priorities including the resuscitation of the patient and the efficient diagnosis and management of the underlying etiology. This review provides a concise evidence-based overview of the core concepts involved in the early postcardiac arrest resuscitation. It will highlight the components of an effective management strategy including addressing hemodynamic, oxygenation, and ventilation goals as well as carefully considering cardiac catheterization and targeted temperature management. An organized approach is paramount to providing effective care to patients in this vulnerable time period.<\/jats:p>","DOI":"10.1177\/0885066619873318","type":"journal-article","created":{"date-parts":[[2019,9,6]],"date-time":"2019-09-06T02:56:24Z","timestamp":1567738584000},"page":"1556-1563","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Optimizing the Early Resuscitation After Out-of-Hospital Cardiac Arrest"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2118-1229","authenticated-orcid":false,"given":"Peter M.","family":"Reardon","sequence":"first","affiliation":[{"name":"Division of Critical Care, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada"},{"name":"Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Hickey","sequence":"additional","affiliation":[{"name":"Division of Critical Care, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada"},{"name":"Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shane W.","family":"English","sequence":"additional","affiliation":[{"name":"Division of Critical Care, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada"},{"name":"Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada"},{"name":"School of Epidemiology and Public Health, University of Ottawa, Ottawa Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Hibbert","sequence":"additional","affiliation":[{"name":"Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada"},{"name":"Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Trevor","family":"Simard","sequence":"additional","affiliation":[{"name":"Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada"},{"name":"Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ariel","family":"Hendin","sequence":"additional","affiliation":[{"name":"Division of Critical Care, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada"},{"name":"Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krishan","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,9,5]]},"reference":[{"key":"bibr1-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.2007.05232.x"},{"key":"bibr2-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1186\/2110-5820-1-45"},{"key":"bibr3-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2008.09.017"},{"key":"bibr4-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)02594-9"},{"key":"bibr5-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2016.06.028"},{"key":"bibr6-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2018.01.019"},{"key":"bibr7-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.95.12.2610"},{"key":"bibr8-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(96)00130-1"},{"key":"bibr9-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-004-2425-z"},{"key":"bibr10-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000262"},{"key":"bibr11-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2016.10.021"},{"key":"bibr12-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2017.11.056"},{"key":"bibr13-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1017\/cem.2018.498"},{"key":"bibr14-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.117.032054"},{"key":"bibr15-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2014.05.021"},{"key":"bibr16-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-015-4051-3"},{"key":"bibr17-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2016.09.019"},{"key":"bibr18-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-015-1067-6"},{"key":"bibr19-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/82.5.813"},{"key":"bibr20-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2018.11.015"},{"key":"bibr21-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2013.02.014"},{"key":"bibr22-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000000228"},{"key":"bibr23-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1136\/emj.2003.005819"},{"key":"bibr24-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-013-2998-5"},{"key":"bibr25-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1097\/MCC.0000000000000493"},{"key":"bibr26-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000000691"},{"key":"bibr27-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000000406"},{"key":"bibr28-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2015.08.023"},{"key":"bibr29-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2015.03.016"},{"key":"bibr30-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000003474"},{"key":"bibr31-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2018.04.028"},{"key":"bibr32-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2017.01.007"},{"key":"bibr33-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-017-1832-9"},{"key":"bibr34-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.14172"},{"key":"bibr35-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-015-0958-x"},{"key":"bibr36-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.12310"},{"key":"bibr37-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1017\/cem.2014.77"},{"key":"bibr38-0885066619873318","first-page":"CD009669","volume":"1","author":"Schumann J","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr39-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-018-5222-9"},{"key":"bibr40-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.04.051"},{"key":"bibr41-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1002\/clc.1980.3.2.116"},{"key":"bibr42-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2016.09.004"},{"key":"bibr43-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2016.10.025"},{"key":"bibr44-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1816897"},{"issue":"1","key":"bibr45-0885066619873318","first-page":"31","volume":"10","author":"Noc M","year":"2014","journal-title":"Euro Intervention"},{"key":"bibr46-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2018.07.007"},{"key":"bibr47-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2018.06.022"},{"key":"bibr48-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1310519"},{"key":"bibr49-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181aa5241"},{"key":"bibr50-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa003289"},{"key":"bibr51-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa012689"},{"key":"bibr52-0885066619873318","author":"American Academy of Neurology","year":"2017","journal-title":"Resuscitation"},{"issue":"1","key":"bibr53-0885066619873318","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.resuscitation.2015.07.052","volume":"98","author":"Howes D","year":"2016","journal-title":"Resuscitation"},{"key":"bibr54-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1089\/ther.2014.0031"},{"key":"bibr55-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2017.01.016"},{"key":"bibr56-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2013.03.038"},{"key":"bibr57-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.161.16.2007"},{"key":"bibr58-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181962ad5"},{"key":"bibr59-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2016.06.019"},{"key":"bibr60-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1007\/s12028-010-9474-7"},{"key":"bibr61-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000630"},{"key":"bibr62-0885066619873318","unstructured":"ELSO Registry. ECLS Registry Report: International Summary, January 2017. ELSO Registry; 2017. https:\/\/www.elso.org\/. Accessed March 5, 2019."},{"key":"bibr63-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2014.01.031"},{"key":"bibr64-0885066619873318","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.06.059"}],"container-title":["Journal of Intensive Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0885066619873318","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0885066619873318","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0885066619873318","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:56:19Z","timestamp":1777503379000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0885066619873318"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,5]]},"references-count":64,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["10.1177\/0885066619873318"],"URL":"https:\/\/doi.org\/10.1177\/0885066619873318","relation":{},"ISSN":["0885-0666","1525-1489"],"issn-type":[{"value":"0885-0666","type":"print"},{"value":"1525-1489","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,5]]}}}