{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:16:23Z","timestamp":1777853783713,"version":"3.51.4"},"reference-count":29,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2021,9,30]],"date-time":"2021-09-30T00:00:00Z","timestamp":1632960000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Intensive Care Med"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>This study aimed to describe the use of awake prone positioning (APP) and conventional oxygen therapy (COT) in patients with suspected coronavirus disease (COVID-19) and respiratory failure in a limited-resource setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a retrospective cohort study of hospitalized patients aged \u226518 years old who were placed in an awake prone position due to hypoxemic respiratory failure and suspected COVID-19. The patients were selected from a tertiary center in Cartagena, Colombia, between March 1, 2020, and August 31, 2020. Demographic, clinical, and laboratory variables were collated, and all the variables were compared between the groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The median age of the participants was 63 (IQR, 48.8-73) years (survivors: 59 [IQR, 43.568] years vs. non-survivors: 70 [IQR, 63-78] years, P\u2009\u2264\u2009.001). Of the 1470 patients admitted for respiratory symptoms, 732 (49.8%) were hospitalized for more than 24\u2005h, and 212 patients developed respiratory failure and required COT and APP (overall hospital mortality, 34% [73\/212]). The mean rank difference in PaO\n                      <jats:sub>2<\/jats:sub>\n                      \/FiO\n                      <jats:sub>2<\/jats:sub>\n                      before and after APP was higher in the survivors than in the non-survivors (201.1-252.6, mean rank difference\u2009=\u200951.5, P\u2009=\u2009.001 vs. 134.1-172.4, mean rank difference\u2009=\u200938.28, P\u2009=\u2009.24, respectively).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>While using COT in conjunction with APP can improve respiratory failure in patients with suspected COVID-19 in low-resource settings, persistent hypoxemia after APP can identify patients with higher mortality risk. More evidence is needed to establish the role of this strategy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/08850666211049333","type":"journal-article","created":{"date-parts":[[2021,9,30]],"date-time":"2021-09-30T12:36:28Z","timestamp":1633005388000},"page":"1347-1353","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Changes in Oxygenation and Clinical Outcomes with Awake Prone Positioning in Patients with Suspected COVID-19 In Low-Resource Settings: A Retrospective Cohort Study"],"prefix":"10.1177","volume":"36","author":[{"given":"Carmelo","family":"Due\u00f1as-Castell","sequence":"first","affiliation":[{"name":"Cl\u00ednica Gesti\u00f3n Salud, Cartagena, Bolivar, Colombia"},{"name":"Intensive Care and Obstetrics Research Group (GRICIO), Universidad de Cartagena, Cartagena, Colombia"},{"name":"Universidad Sim\u00f3n Bol\u00edvar, Barranquilla, Colombia"},{"name":"Universidad 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