{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T22:10:30Z","timestamp":1793398230958,"version":"4.5.0"},"reference-count":36,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T00:00:00Z","timestamp":1651017600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Intensive Care Med"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Mobilization and acute rehabilitation are essential in the intensive care unit (ICU), with substantial evidence supporting their benefits. This study aimed to characterize ICU mobilization practices during the COVID-19 pandemic for patients with and without COVID-19.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a secondary analysis of an international point prevalence study. All ICUs across the world were eligible to participate and were required to enroll all patients in each ICU on the survey date, 27 January 2021. The primary outcome was the achievement of mobilization at the level of sitting over the edge of the bed. Independent factors associated with mobilization, including COVID-19 infection, were analyzed by multivariable analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 135 ICUs in 33 countries participated, for inclusion of 1229 patients. Among patients who were not receiving mechanical ventilation (MV), those with COVID-19 infection were mobilized more than those without COVID-19 (60% vs. 34%, p\u2009&lt;\u20090.001). Among patients who were receiving MV, mobilization was low in both groups (7% vs. 9%, p\u2009=\u2009.56). These findings were consistent irrespective of ICU length of stay. Multivariable analysis showed that COVID-19 infection was associated with achievement of mobilization in patients without (adjusted odds ratio [aOR]\u2009=\u20094.48, 95% confidence interval [CI]\u2009=\u20092.71-7.42) and with MV (aOR\u2009=\u20092.13, 95% CI\u2009=\u20091.00-4.51). Factors that prevented mobilization were prone positioning in patients without MV and continuous use of neuromuscular blockade and sedation agents in patients with MV, whereas facilitating factors were the presence of targets\/goals in both groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Mobilization rates for ICU patients across the globe are severely low, with the greatest immobility observed in mechanically ventilated patients. Although COVID-19 is not an independent barrier to the mobilization of patients with or without MV, this study has highlighted the current lack of mobility practice for all ICU patients during the COVID-19 pandemic. (299 words)<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/08850666221097644","type":"journal-article","created":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T04:42:27Z","timestamp":1651034547000},"page":"1256-1264","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":24,"title":["Mobilization and Rehabilitation Practice in ICUs During the COVID-19 Pandemic"],"prefix":"10.1177","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6867-1420","authenticated-orcid":false,"given":"Keibun","family":"Liu","sequence":"first","affiliation":[{"name":"Critical Care Research Group, Faculty of Medicine, University of Queensland and The Prince Charles Hospital, Brisbane, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8481-0294","authenticated-orcid":false,"given":"Kensuke","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, Hitachi General Hospital, Hitachi, Ibaraki, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sapna R.","family":"Kudchadkar","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care Medicine, Department of Physical Medicine and Rehabilitation, and Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajime","family":"Katsukawa","sequence":"additional","affiliation":[{"name":"Japanese Society for Early Mobilization, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Nydahl","sequence":"additional","affiliation":[{"name":"Nursing Research, Department of Anesthesiology and Intensive Care Medicine, University Hospital of Schleswig-Holstein, Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugene Wesley","family":"Ely","sequence":"additional","affiliation":[{"name":"Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Vanderbilt University School of Medicine, Nashville, TN, USA"},{"name":"Geriatric Research Education and Clinical Center (GRECC), Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2387-7772","authenticated-orcid":false,"given":"Kunihiko","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, M&D Data Science Center, Tokyo Medical and Dental University, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeaki","family":"Inoue","sequence":"additional","affiliation":[{"name":"Emergency and Critical Care Center, Kobe University Hospital, Kobe, Japan"},{"name":"Department of Disaster and Emergency Medicine, Kobe University, Graduate School of Medicine, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0140-283X","authenticated-orcid":false,"given":"Osamu","family":"Nishida","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care Medicine, Fujita Health University School of Medicine, Toyoake, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,4,27]]},"reference":[{"key":"bibr1-08850666221097644","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000005285"},{"key":"bibr2-08850666221097644","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31827ca637"},{"key":"bibr3-08850666221097644","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000003765"},{"key":"bibr4-08850666221097644","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000002175"},{"key":"bibr5-08850666221097644","doi-asserted-by":"publisher","DOI":"10.1177\/0885066617728486"},{"key":"bibr6-08850666221097644","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000000149"},{"key":"bibr7-08850666221097644","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000002058"},{"key":"bibr8-08850666221097644","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0223151"},{"key":"bibr9-08850666221097644","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000004808"},{"key":"bibr10-08850666221097644","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(20)30161-2"},{"key":"bibr11-08850666221097644","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-020-05967-x"},{"key":"bibr12-08850666221097644","volume":"8","author":"Liu K","year":"2021","journal-title":"Front Med (Lausanne)."},{"key":"bibr13-08850666221097644","doi-asserted-by":"publisher","DOI":"10.1097\/CCE.0000000000000353"},{"key":"bibr14-08850666221097644","unstructured":"Ministry of Health, Labour and Welfare, Japan. 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