{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T04:06:58Z","timestamp":1792642018861,"version":"4.5.0"},"reference-count":18,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T00:00:00Z","timestamp":1698624000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Intensive Care Med"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:p>Purpose: We aim to assess the impact of the exposure to deep versus light sedation by a critical care transport agency during prehospital and interhospital transport on hospital sedation levels, medication exposure, and outcomes of mechanically ventilated patients. Materials and Methods: Retrospective cohort review of mechanically ventilated adult critical care transport patients from January 1, 2019, to March 11, 2020, who arrived at an academic medical center. The primary outcome was the correlation of deep sedation during transport with deep sedation within the first 48\u2005h of hospitalization (defined as Richmond Agitation Sedation Scale [RASS] \u22123 to \u22125). The secondary outcomes were duration of mechanical ventilation, hospital length of stay, intensive care unit (ICU) length of stay, inpatient mortality, delirium within 48\u2005h, and coma within 48\u2005h. Results: One hundred and ninety-eight patients were included, of whom 183 (92.4%) were deeply sedated during transport which persisted through the first 48\u2005h of hospital care. Deep sedation during transport was not correlated with deep sedation in the hospital within the first 48\u2005h (OR 2.41; 95% CI, 0.48-12.02). There was no correlation with hospital length of stay, ICU length of stay, duration of mechanical ventilation, or hospital mortality. Deep sedation during transport was not correlated with delirium or coma within the first 48\u2005h of hospitalization. There was a negligible correlation between final transport RASS and initial hospital RASS which did not differ based on the lapsed time from handoff (&lt;1\u2005h corr. coeff. 0.23; \u22651\u2005h corr. coeff. 0.25). Conclusions: Deep sedation was observed during critical care transport in this cohort and was not correlated with deep sedation during the first 48\u2005h of hospitalization. The transition of care between the transport team and the hospital team may be an opportunity to disrupt therapeutic momentum and re-evaluate sedation decisions.<\/jats:p>","DOI":"10.1177\/08850666231210802","type":"journal-article","created":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T02:27:32Z","timestamp":1698719252000},"page":"429-438","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Correlation of Sedation Depth During Critical Care Transport and Hospitalization"],"prefix":"10.1177","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3322-4556","authenticated-orcid":false,"given":"Matthew A.","family":"Roginski","sequence":"first","affiliation":[{"name":"Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA"},{"name":"Dartmouth Geisel School of Medicine, Hanover, NH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew C.","family":"Carroll","sequence":"additional","affiliation":[{"name":"Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Micah L.","family":"Trautwein","sequence":"additional","affiliation":[{"name":"Dartmouth Geisel School of Medicine, Hanover, NH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evan D.","family":"Watkins","sequence":"additional","affiliation":[{"name":"Dartmouth Geisel School of Medicine, Hanover, NH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0176-5657","authenticated-orcid":false,"given":"Alyson M.","family":"Esteves","sequence":"additional","affiliation":[{"name":"Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,10,30]]},"reference":[{"key":"bibr1-08850666231210802","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000003071"},{"key":"bibr2-08850666231210802","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-022-06806-x"},{"key":"bibr3-08850666231210802","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.901343"},{"key":"bibr4-08850666231210802","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-019-2394-9"},{"key":"bibr5-08850666231210802","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2017.05.041"},{"key":"bibr6-08850666231210802","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-022-04042-9"},{"key":"bibr7-08850666231210802","unstructured":"Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome | NEJM. 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