{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T23:20:42Z","timestamp":1791415242873,"version":"4.3.3"},"reference-count":41,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Intensive Care Med"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:p>\n                    Adequate fluid therapy is crucial to maintain organ function after burn trauma. Major burns lead to a systemic response with fluid loss and cardiac dysfunction. To guide fluid therapy, measurement of cardiac pre- and afterload is helpful. Whereas cardiac function is usually measured after admission to intensive care unit (ICU), in this study, hemodynamic monitoring was performed directly after arrival at hospital. We conducted a prospective cohort study with inclusion of 19 patients (male\/female 13\/6, 55\u2009\u00b1\u200918 years, mean total body surface area 36\u2009\u00b1\u200919%). Arterial waveform analysis (PulsioFlexProAqt\n                    <jats:sup>\u00ae<\/jats:sup>\n                    , Getinge) was implemented immediately after admission to hospital to measure cardiac pre- and afterload and to guide resuscitation therapy. Cardiac parameters 3.75 (2.67-6.0) h after trauma were normal regarding cardiac index (3.45\u2009\u00b1\u20090.82) L\/min\/m\u00b2, systemic vascular resistance index (1749\u2009\u00b1\u2009533) dyn sec\/cm\n                    <jats:sup>5<\/jats:sup>\n                    m\n                    <jats:sup>2<\/jats:sup>\n                    , and stroke volume (SV; 80\u2009\u00b1\u200920) mL. Stroke volume variation (SVV) was increased (21\u2009\u00b1\u20097) % and associated with mortality (mean SVV survivors vs nonsurvivors 18.92 (\u00b16.37) % vs 27.6 (\u00b15.68) %, P\u2009=\u2009.017). Stroke volume was associated with mortality at the time of ICU-admission (mean SV survivors vs nonsurvivors 90 (\u00b120) mL vs 50 (\u00b10) mL, P\u2009=\u2009.004). Changes after volume challenge were significant for SVV (24\u2009\u00b1\u20099 vs19\u2009\u00b1\u20098%, P\u2009=\u2009.01) and SV (68\u2009\u00b1\u200924 vs 76\u2009\u00b1\u200926 mL, P\u2009=\u2009.03). We described association of SVV and SV with survival of severely burned patients in an observational study. This indicates high valence of those parameters in the early postburn period. The use of an autocalibrated device enables a very early monitoring of parameters relevant to burn shock survival.\n                  <\/jats:p>","DOI":"10.1177\/08850666241268470","type":"journal-article","created":{"date-parts":[[2024,8,2]],"date-time":"2024-08-02T01:05:05Z","timestamp":1722560705000},"page":"164-171","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Stroke Volume and Stroke Volume Variation, but not Cardiac Index Is Associated With Survival of Majorly Burned Patients in Early Burn Shock"],"prefix":"10.1177","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6732-0920","authenticated-orcid":false,"given":"Marianne","family":"Kruse","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, Intensive Care and Pain Medicine, BG Klinikum Unfallkrankenhaus Berlin, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Plettig","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Intensive Care and Pain Medicine, BG Klinikum Unfallkrankenhaus Berlin, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9086-9065","authenticated-orcid":false,"given":"David","family":"Josuttis","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Intensive Care and Pain Medicine, BG Klinikum Unfallkrankenhaus Berlin, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Guembel","sequence":"additional","affiliation":[{"name":"Department of Trauma and Orthopaedic Surgery, BG Klinikum Unfallkrankenhaus Berlin, Berlin, Germany"},{"name":"Department of Trauma, Reconstructive Surgery and Rehabilitation Medicine, University Medicine Greifswald, Greifswald, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9984-6908","authenticated-orcid":false,"given":"Claas","family":"Guethoff","sequence":"additional","affiliation":[{"name":"Centre for Clinical Research, Biostatistics, BG Klinikum Unfallkrankenhaus Berlin, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernd","family":"Hartmann","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Burn Centre, BG Klinikum Unfallkrankenhaus Berlin, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Kuepper","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Burn Centre, BG Klinikum Unfallkrankenhaus Berlin, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volker","family":"Gebhardt","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Intensive Care and Pain Medicine, BG Klinikum Unfallkrankenhaus Berlin, Berlin, Germany"},{"name":"Medical Faculty Mannheim of Heidelberg University, Ruprecht-Karls-University Heidelberg, Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc Dominik","family":"Schmittner","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Intensive Care and Pain Medicine, BG Klinikum Unfallkrankenhaus Berlin, Berlin, Germany"},{"name":"Medical Faculty Mannheim of Heidelberg University, Ruprecht-Karls-University Heidelberg, Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,8,1]]},"reference":[{"key":"bibr1-08850666241268470","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1968.tb14738.x"},{"key":"bibr2-08850666241268470","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-197308000-00020"},{"issue":"1","key":"bibr3-08850666241268470","first-page":"26","volume":"25","author":"Abu-Sittah GS","year":"2012","journal-title":"Ann Burns Fire 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