{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T02:20:53Z","timestamp":1791512453941,"version":"4.3.4"},"reference-count":36,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T00:00:00Z","timestamp":1727654400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Intensive Care Med"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:p>\n                    <jats:bold>Objective:<\/jats:bold>\n                    Develop an inpatient predictive model of parental post-traumatic stress (PTS) following their child's care in the Pediatric Intensive Care Unit (PICU).\n                    <jats:bold>Design:<\/jats:bold>\n                    Prospective observational cohort.\n                    <jats:bold>Setting:<\/jats:bold>\n                    Two tertiary care children's hospitals with mixed medical\/surgical\/cardiac PICUs.\n                    <jats:bold>Subjects:<\/jats:bold>\n                    Parents of patients admitted to the PICU.\n                    <jats:bold>Interventions:<\/jats:bold>\n                    None.\n                    <jats:bold>Measurements and Main Results:<\/jats:bold>\n                    Preadmission and admission data from 169 parents of 129 children who completed follow up screening for parental post-traumatic stress symptoms at 3-9 months post PICU discharge were utilized to develop a predictive model estimating the risk of parental PTS 3-9 months after hospital discharge. The parent cohort was predominantly female (63%), partnered (75%), and working (70%). Child median age was 3 years (IQR 0.36-9.04), and more than half had chronic illnesses (56%) or previous ICU admissions (64%). Thirty-five percent (60\/169) of parents met criteria for PTS (&gt;9 on the Post-traumatic Stress Disorder Symptom Scale-Interview). The machine learning model (XGBoost) predicted subjects with parental PTS with 76.7% accuracy, had a sensitivity of 0.83 (95% CI 0.586, 0.964), a specificity of 0.72 (95% CI 0.506, 0.879), a precision of 0.682 (95% CI 0.451, 0.861) and number needed to evaluate of 1.47 (95% CI 1.16, 1.98). The area under the receiver operating curve was 0.78 (95% CI 0.64, 0.92). The most important predictive pre-admission and admission variables were determined using the Local Interpretable Model-Agnostic Explanation, which identified seven variables used 100% of the time. Composite variables of parental history of mental illness and traumatic experiences were most important.\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    A machine learning model using parent risk factors predicted subsequent PTS at 3-9 months following their child's PICU discharge with an accuracy of 76.7% and number needed to evaluate of 1.47. This performance is sufficient to identify parents who are at risk during hospitalization, making inpatient and acute post admission mitigation initiatives possible.\n                  <\/jats:p>","DOI":"10.1177\/08850666241287442","type":"journal-article","created":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T04:38:25Z","timestamp":1727671105000},"page":"396-403","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Predicting Parental Post-Traumatic Stress Symptoms Following their Child's Stay in a Pediatric Intensive Care Unit, Prior to Discharge"],"prefix":"10.1177","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2130-9114","authenticated-orcid":false,"given":"Mekela M.","family":"Whyte-Nesfield","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Division of Pediatric Critical Care, Children's National Hospital, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo A.","family":"Trujillo Rivera","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Pediatric Critical Care, Children's National Hospital, Washington, DC, USA"},{"name":"Children's National Research Institute, Children's National Hospital, Washington, DC, USA"},{"name":"George Washington University, School of Medicine and Health Sciences, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Kaplan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Pediatric Critical Care, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Pediatric Critical Care, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamela S.","family":"Hinds","sequence":"additional","affiliation":[{"name":"Children's National Research Institute, Children's National Hospital, Washington, DC, USA"},{"name":"George Washington University, School of Medicine and Health Sciences, Washington, DC, USA"},{"name":"Department of Nursing Science, Professional Practice &amp; Quality, Children's National Hospital, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murray M.","family":"Pollack","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Pediatric Critical Care, Children's National Hospital, Washington, DC, USA"},{"name":"Children's National Research Institute, Children's National Hospital, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,9,30]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0000000000001476"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0b013e3182196a8f"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0000000000001985"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0000000000003129"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.iccn.2017.06.003"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-004-2310-9"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.anclin.2018.09.012"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0000000000001894"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.113.6.e597"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2018.02.006"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1177\/08850666221100482"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.18.1737"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1037\/1040-3590.12.1.61"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v69n0606"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1037\/pas0000259"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199605000-00004"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-1987"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200007000-00072"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)82544-2"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0000000000002905"},{"issue":"2","key":"e_1_3_2_22_2","first-page":"267","article-title":"Parents\u2019 Challenges beyond the Pediatric Intensive Care Unit: Fraying at the Seams while Balancing between Two Worlds, Home and Hospital","volume":"9","author":"Alzawad Z","year":"2022","unstructured":"Alzawad Z, Lewis FM, Walker A. 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