{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T23:03:09Z","timestamp":1780095789905,"version":"3.54.0"},"reference-count":25,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T00:00:00Z","timestamp":1760486400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"the Strong Foundation Program of Naval Medical Center","award":["24QJJH12"],"award-info":[{"award-number":["24QJJH12"]}]},{"name":"the Youth Research Projects of Changning District Health Commission","award":["2023QN23"],"award-info":[{"award-number":["2023QN23"]}]},{"name":"the Key Medical Specialties of Changning District Health Commission","award":["20231005"],"award-info":[{"award-number":["20231005"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Intensive Care Med"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Arterial catheterization serves as a cornerstone monitoring modality in septic shock management, enabling continuous hemodynamic assessment and serial blood gas analysis. Despite its widespread use, mortality benefits and optimal timing for catheter insertion remains undefined.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An analysis of clinical data from 6,485 critically ill adult patients, identified as meeting the Sepsis-3 criteria for septic shock, was conducted utilizing the MIMIC-IV database. Through entropy-balanced propensity score matching (PSM, 1:1 ratio) and doubly robust estimation with inverse probability weighting, we compared outcomes between catheterized (\u226424\u2005h post-admission) and non-catheterized groups. Restricted cubic spline (RCS) modeling characterized nonlinear temporal associations. The evaluation encompassed both primary and secondary endpoints, including 28-day mortality, mortality within the ICU and hospital settings, length of stay, CRRT requirements, and physiological resuscitation metrics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>After PSM (1,416 patients from initial 6,485) with 1:1 ratio, arterial catheterization exhibited significantly reduced mortality across all measured outcomes compared to non-catheterized controls: 28-day mortality (26.1% vs 43.9%; aHR 0.62, 95%CI 0.51-0.75), ICU mortality (aHR 0.76, 0.61-0.94), and in-hospital mortality (HR 0.70, 0.58-0.86), all P\u2009&lt;\u2009.05. Arterial catheterization was associated with a shorten ICU stay by 0.52 days (95%CI 0.18-0.82, P\u2009=\u2009.002) and improved physiological parameters. Restricted cubic splines identified optimal intervention timing at 204\u2013290\u2005min post-admission through U-shaped mortality risk association.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In a cohort of critically ill patients with septic shock, early peripheral arterial catheterization is significantly associated with improved 28-day mortality outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/08850666251385496","type":"journal-article","created":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T18:15:29Z","timestamp":1760552129000},"page":"578-590","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Association Between Early Arterial Catheterization and Prognosis in Patients with Septic Shock: A Retrospective Propensity Score 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