{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T11:15:58Z","timestamp":1788520558233,"version":"build-2803163510"},"reference-count":22,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T00:00:00Z","timestamp":1775260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Intensive Care Med"],"published-print":{"date-parts":[[2026,10]]},"abstract":"\n Purpose<\/jats:title>\n \n Serratia marcescens<\/jats:italic>\n is a well-recognized hospital-acquired pathogen frequently implicated in outbreaks in neonatal and pediatric intensive care units. We compared clinical characteristics of infants with\n Serratia<\/jats:italic>\n bloodstream infections (BSI) to those with non-\n Serratia<\/jats:italic>\n gram-negative BSI.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n A retrospective case-control study comparing infants (0-2 y\/o) hospitalized at our referral pediatric cardiac intensive care unit (PCICU), who acquired gram-negative blood cultures, during 2012\u20132022. Patients were categorized into two groups:\n S. marcescens<\/jats:italic>\n BSI versus non-\n Serratia<\/jats:italic>\n gram-negative BSI. Demographic and clinical data were extracted from our medical databases.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Of 112 patients meeting inclusion criteria, 40 (36%) had\n Serratia<\/jats:italic>\n BSI and 72 (64%) non-\n Serratia<\/jats:italic>\n gram-negative BSI. Blood stream infection with\n Serratia<\/jats:italic>\n occurred later postoperatively (median 15 vs 7 days,\n p<\/jats:italic>\n \u2009<\u2009.01), were associated with less pre-infection inotropic support (median VIS 0 vs 5,\n p<\/jats:italic>\n \u2009<\u2009.01) and higher rates of multisite involvement (35% vs 18%,\n p<\/jats:italic>\n \u2009=\u2009.04). Duration of indwelling vascular catheters at time of infection was longer in the\n Serratia<\/jats:italic>\n group (median 10 vs 7 days,\n p<\/jats:italic>\n \u2009=\u2009.03). No associated mortality was attributed to\n Serratia<\/jats:italic>\n BSI, as compared to a 5.6% mortality rate in the non-\n Serratia<\/jats:italic>\n group.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Serratia<\/jats:italic>\n BSI in the PCICU tends to develop later during hospitalization, involves more multiple infection sites, and is associated with longer vascular catheters dwell durations at the time of infection.\n Serratia<\/jats:italic>\n infections appeared sporadically throughout the year without seasonal clustering. This supports the importance of stringent infection control practices and warrants prospective studies on prevention strategies.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/08850666261424210","type":"journal-article","created":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T07:29:12Z","timestamp":1775287752000},"page":"992-998","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Characteristics of\n Serratia marcescens<\/i>\n Bacteremia in Comparison to Other Gram-Negative Bacteremia in Infants in the Pediatric Cardiac Intensive Care Unit A Case-Control Study (2012-2022)"],"prefix":"10.1177","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7582-2218","authenticated-orcid":false,"given":"Eran","family":"Shostak","sequence":"first","affiliation":[{"name":"Schneider Children's Medical Center"},{"name":"Gray Faculty of Medical & Health Sciences, Tel Aviv University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliana","family":"Fanous","sequence":"additional","affiliation":[{"name":"Schneider Children's Medical Center of Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ofer","family":"Schiller","sequence":"additional","affiliation":[{"name":"Schneider Children's Medical Center"},{"name":"Gray Faculty of Medical & Health Sciences, Tel Aviv University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yael","family":"Feinstein","sequence":"additional","affiliation":[{"name":"Schneider Children's Medical Center"},{"name":"Gray Faculty of Medical & Health Sciences, Tel Aviv University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magda","family":"Zomer","sequence":"additional","affiliation":[{"name":"Schneider Children's Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tzippy","family":"Shochat","sequence":"additional","affiliation":[{"name":"Rabin Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilat","family":"Livni","sequence":"additional","affiliation":[{"name":"Gray Faculty of Medical & Health Sciences, Tel Aviv University"},{"name":"Schneider Children's Medical Center of Israel"},{"name":"Pediatric Infectious Diseases Unit, Schneider Children's Medical Center, Petach Tikva, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,4,4]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1086\/587969"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2006.12.012"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.anpedi.2017.04.007"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-014-0654-9"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2011.03.020"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijheh.2009.09.003"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2008.00953.x"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2004.08.003"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1086\/339046"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/apa.16542"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pedneo.2017.11.014"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2009.03.071"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-016-0922-y"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/aem.00105-23"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00017-11"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1080\/00031305.2016.1154108"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2008.04.001"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03570.x"},{"issue":"8","key":"e_1_3_2_20_2","article-title":"Recognition and prevention of multidrug-resistant gram-negative bacteria in the intensive care unit: Infection control in the intensive care unit.","volume":"38","author":"Maragakis LL","year":"2010","unstructured":"Maragakis LL. 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