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Treatment of pure fibroin as well as polyethylene glycol- blended films with 90% organic solvent for 60 min induces optimal surface hydrophobicity and maximum conversion of the secondary structure from random coil to \u03b2 sheet. Long-term cell viability studies reveal that methanol and isopropanol-treated pure and blended films support cell adhesion, proliferation, and viability.<\/jats:p>","DOI":"10.1177\/0885328208094261","type":"journal-article","created":{"date-parts":[[2008,9,18]],"date-time":"2008-09-18T20:54:22Z","timestamp":1221771262000},"page":"497-517","source":"Crossref","is-referenced-by-count":6,"title":["Surface Treatment of Pure and PEG-4000 Blended Fibroin Films and their                Characterizations as Matrices for\n                    <i>in vitro<\/i>\n                    Fibroblast Culture"],"prefix":"10.1177","volume":"23","author":[{"given":"Chitrangada","family":"Acharya","sequence":"first","affiliation":[{"name":"Department of Biotechnology, Indian Institute of Technology                        Kharagpur-721302, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anindya","family":"Dutta","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, Indian Institute of Technology                        Kharagpur-721302, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.C.","family":"Kundu","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, Indian Institute of Technology                        Kharagpur-721302, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2008,9,18]]},"reference":[{"issue":"136","key":"atypb1","author":"Lee, Y.","year":"1999","journal-title":"Bulletin"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1271\/bbb.66.2715"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1016\/0020-1790(77)90026-9"},{"key":"atypb4","unstructured":"Tamura, T.                 and                     Kubota, T.                 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