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With the application on clinical, the problems of elastic modulus is relatively high, subsidence of adjacent vertebral implants and stress shielding after surgery have gradually exposed. In this paper, metal rubber made from titanium alloy wire was used to prepare cervical fusion cage (CFC), which was a porous material with buffering and vibration damping properties. The C5\/C6 segment of the goat cervical vertebra was used as the research object. The shape parameters of the CFC were determined by combining the three-dimensional model data of the cervical vertebra and the structural characteristics of the natural intervertebral disc. The force of CFC under different working conditions were simulated and analyzed by finite element simulation. Then three kinds of metal rubber core (MRC) were prepared by medical titanium alloy wire (TC4), and their mechanical properties and fatigue strength were experimentally studied. With the increases of density, the mechanical properties of MRC improved. The variation range of the loss factor \u03b7 under different amplitudes and frequencies were 20% and 16.3%, respectively. After one million vibrations, the wear rate was 0.131\u00a0g\/MC; after five million vibrations, the wear rate was 0.158\u00a0g\/MC, which was similar to the existing clinical prosthesis wear rate. The MRC has sufficient mechanical strength. Compared with the existing clinical prostheses, it has a longer service life and has broad application prospects.<\/jats:p>","DOI":"10.1177\/08853282221146692","type":"journal-article","created":{"date-parts":[[2022,12,19]],"date-time":"2022-12-19T09:31:07Z","timestamp":1671442267000},"page":"1029-1041","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Design and mechanical properties of cervical fusion cage based on porous entangled metal rubber material"],"prefix":"10.1177","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3233-3785","authenticated-orcid":false,"given":"Zhiying","family":"Ren","sequence":"first","affiliation":[{"name":"School of Mechanical Engineering and Automation, Institute of Metal Rubber and Vibration Noise, Fuzhou University, Fuzhou 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