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Interventions that prevent SV and improve SV care-seeking behaviors for sexual minority students are lacking.\n                    <jats:italic>Giving Information for Trauma Support and Safety (GIFTSS)<\/jats:italic>\n                    is an evidence-based universal SV intervention implemented by providers during college health and counseling visits. Compared to controls,\n                    <jats:italic>GIFTSS<\/jats:italic>\n                    participants reported greater self-efficacy to use SV harm reduction strategies and SV disclosure during clinical visits. However,\n                    <jats:italic>GIFTSS\u2019<\/jats:italic>\n                    effectiveness for sexual minority participants is unknown. The current study examines whether sexual orientation moderates\n                    <jats:italic>GIFTSS\u2019<\/jats:italic>\n                    effects on numerous SV-related outcomes (i.e., to test whether intervention effects at 4 and 12\u2009months differed based on sexual orientation). Across 28 college campuses in Pennsylvania and West Virginia, 2,291 students participated in a two-arm cluster-randomized controlled trial. We used mixed models with two- and three-way interaction terms to test whether sexual orientation modified\n                    <jats:italic>GIFTSS\u2019<\/jats:italic>\n                    effects at 4- and 12-month follow-up on participants\u2019: SV recognition; knowledge of and self-efficacy to enact SV harm reduction strategies; intentions to intervene; knowledge of and self-efficacy to use SV-related services; SV disclosure during visits; and recent SV exposure. Overall, 22.1% of participants were sexual minorities (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u2009507). Sexual orientation moderated\n                    <jats:italic>GIFTSS<\/jats:italic>\n                    effectiveness as indicated by significant three-way interaction (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u2009.01) at 12-month follow-up, and knowledge of SV services decreased for heterosexual participants (\u03b2\u2009=\u2009\u2212.23) but increased for sexual minority participants (\u03b2\u2009=\u2009.23). Our study indicates that universal provider-based education may promote greater knowledge of SV services among sexual minority than heterosexual participants, and population-specific interventions are needed that reduce sexual minority students\u2019 SV exposure, service utilization, and other critical aspects of SV prevention on university campuses.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Clinical Trial Registration:<\/jats:bold>\n                    Registry name: College Health Center-based Alcohol and Sexual Violence Intervention (GIFTSS), Registration number: NCT02355470, Web link:\n                    <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT02355470\">https:\/\/clinicaltrials.gov\/ct2\/show\/NCT02355470<\/jats:ext-link>\n                    , Deidentified individual participant data will not be made available.\n                  <\/jats:p>","DOI":"10.1177\/08862605241253031","type":"journal-article","created":{"date-parts":[[2024,5,18]],"date-time":"2024-05-18T11:56:32Z","timestamp":1716033392000},"page":"582-606","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Universal Sexual Violence Intervention Effects in a Cluster-Randomized Trial: Moderation by Sexual Orientation"],"prefix":"10.1177","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8350-0075","authenticated-orcid":false,"given":"Robert W. 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