{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:24:49Z","timestamp":1777379089115,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["AIDS Research and Human Retroviruses"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:p>The human T-lymphotropic virus 1 (HTLV-1) affects millions globally, notably in Brazil. The classical neurological presentation of this infection is HTLV-1-associated myelopathy\/tropical spastic paraparesis (HAM\/TSP). There is limited information on its association with lipid disorders and cardiovascular risks. Here, we compare the lipid profile of 30 people with HTLV-1 and HAM\/TSP to 73 people with HTLV-1 without evidence of HAM\/TSP from a Brazilian reference center between July 2021 and September 2023. People with HAM\/TSP had lower levels of high-density lipoprotein and higher levels of low-density lipoprotein (LDL) and total cholesterol than people without HAM\/TSP. In addition, people with HAM\/TSP had a sixfold risk increase for elevated LDL. Therefore, patients with HAM\/TSP show an adverse lipid profile, indicating higher dyslipidemia and cardiovascular risks. Regular lipid monitoring in this group is recommended.<\/jats:p>","DOI":"10.1177\/08892229251365946","type":"journal-article","created":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T08:13:42Z","timestamp":1760170422000},"page":"500-503","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Adverse Lipid Profiles and Increased Cardiovascular Risks in People with HAM\/TSP"],"prefix":"10.1177","volume":"41","author":[{"given":"Ana Fl\u00e1via","family":"Novaes","sequence":"first","affiliation":[{"name":"Universidade Federal da Bahia\u2014Instituto Multidisciplinar em Sa\u00fade, Vit\u00f3ria da Conquista, Bahia, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qesya Rodrigues","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Universidade Federal da Bahia\u2014Instituto Multidisciplinar em Sa\u00fade, Vit\u00f3ria da Conquista, Bahia, 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The role of TRIM family in metabolic associated fatty liver disease. 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