{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T10:02:45Z","timestamp":1784628165715,"version":"3.55.0"},"reference-count":15,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T00:00:00Z","timestamp":1756771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["AIDS Research and Human Retroviruses"],"published-print":{"date-parts":[[2025,12,1]]},"abstract":"<jats:p>The frequent recombination between subtypes has driven significant HIV-1 genetic diversity in recent years, especially in some areas with co-circulation of multiple subtypes. In this study, we obtained nearly full-length genome sequences of two novel HIV-1 B\/CRF01_AE\/CRF07_BC recombinants from BD076A and BDL161, with lengths of 8718 bp (HXB2:772-9490) and 8851 bp (HBB2:759-9610), respectively. Both recombination breakpoint and Bootscanning analysis revealed that the recombinant structure of BD076A was based on the CRF07_BC backbone, with the insertion of one subtype B and one CRF01_AE gene fragment, containing four subregions. Similarly, BDL161 was based on the CRF07_BC backbone, with the insertion of one subtype B fragment and two CRF01_AE gene fragments, containing seven subregions. These findings highlight the importance of sustaining molecular epidemiological surveillance to monitor HIV-1 diversity and take effective prevention and control strategies in the region.<\/jats:p>","DOI":"10.1177\/08892229251374704","type":"journal-article","created":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T08:00:57Z","timestamp":1762243257000},"page":"552-558","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Characterization of Two Novel HIV-1B\/CRF01_AE\/CRF07_BC Recombinant Forms Among Men Who Have Sex with Men in Hebei Province, China"],"prefix":"10.1177","volume":"41","author":[{"given":"Feng","family":"Zhao","sequence":"first","affiliation":[{"name":"Infection Division, The People\u2019s Hospital of Baoding, Baoding, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziting","family":"Liu","sequence":"additional","affiliation":[{"name":"Laboratory Department, The Baoding Center for Disease Control and Prevention, Baoding, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianru","family":"Jia","sequence":"additional","affiliation":[{"name":"Infection Division, The People\u2019s Hospital of Baoding, Baoding, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Zhang","sequence":"additional","affiliation":[{"name":"Infection Division, The People\u2019s Hospital of Baoding, Baoding, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-7962-586X","authenticated-orcid":false,"given":"Haoxi","family":"Shi","sequence":"additional","affiliation":[{"name":"Clinical Laboratory, The People\u2019s Hospital of Baoding, Baoding, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4612-1900","authenticated-orcid":false,"given":"Weiguang","family":"Fan","sequence":"additional","affiliation":[{"name":"Clinical Laboratory, The People\u2019s Hospital of Baoding, Baoding, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-1499-5655","authenticated-orcid":false,"given":"Sisi","family":"Chen","sequence":"additional","affiliation":[{"name":"Clinical Laboratory, The People\u2019s Hospital of Baoding, Baoding, China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,9,2]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-200216004-00002"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2016"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0030443"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep19279"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1089\/AID.2018.0226"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1089\/AID.2019.0196"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2022.01.017"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-64156-8"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2024.0122"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1089\/AID.2019.0149"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1089\/AID.2016.0029"},{"key":"e_1_3_5_13_2","unstructured":"Office of Health China Action Promotion Committee. 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