{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T17:16:00Z","timestamp":1783444560035,"version":"3.54.6"},"reference-count":15,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T00:00:00Z","timestamp":1766966400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["AIDS Research and Human Retroviruses"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:p>\n                    The China\u2013Myanmar border region is recognized as a hotspot for the emergence of HIV-1 recombinant forms. This study identified a novel HIV-1 circulating recombinant form (CRF) in this area, designated CRF184_BC. Near-full-length genome sequences were obtained from four individuals infected through heterosexual contact: one Chinese individual and three Burmese individuals. These sequences formed a distinct monophyletic clade with strong bootstrap support, separate from all known subtypes\/CRFs. Recombination analysis revealed a conserved mosaic structure comprising four subtype C segments and three subtype B segments: I\n                    <jats:sub>C<\/jats:sub>\n                    (790\u20132897), II\n                    <jats:sub>B<\/jats:sub>\n                    (2898\u20133208), III\n                    <jats:sub>C<\/jats:sub>\n                    (3209\u20135983), IV\n                    <jats:sub>B<\/jats:sub>\n                    (5984\u20136435), V\n                    <jats:sub>C<\/jats:sub>\n                    (6436\u20138821), VI\n                    <jats:sub>B<\/jats:sub>\n                    (8822\u20138969), and VII\n                    <jats:sub>C<\/jats:sub>\n                    (8970\u20139468). Bayesian Markov chain Monte Carlo analysis indicated that CRF184_BC emerged between the mid-2000s and the early 2010s. Identifying emerging CRFs highlights the ongoing dynamic evolution of HIV-1 in this region and emphasizes the need for enhanced molecular surveillance to inform effective public health strategies and vaccine development efforts.\n                  <\/jats:p>","DOI":"10.1177\/08892229251410288","type":"journal-article","created":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T07:26:51Z","timestamp":1767079611000},"page":"77-81","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Identification of a Novel HIV-1 Circulating Recombinant Form (CRF184_BC) Among Heterosexual Populations Along the China\u2013Myanmar Border Region"],"prefix":"10.1177","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9699-7524","authenticated-orcid":false,"given":"Min","family":"Chen","sequence":"first","affiliation":[{"name":"Yunnan International Joint Laboratory of Public Health and Disease Control, Yunnan Center for Disease Control and Prevention, Kunming, Yunnan, China."},{"name":"School of Public Health, Kunming Medical University, Kunming, Yunnan, China."},{"name":"Yunnan Provincial Key Laboratory of Public Health and Biosafety &amp; Public Laboratory Center, Yunnan Center for Disease Control and Prevention, Kunming, Yunnan, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huichao","family":"Chen","sequence":"additional","affiliation":[{"name":"Yunnan Provincial Key Laboratory of Public Health and Biosafety &amp; Institute for AIDS\/STD Control and Prevention, Yunnan Center for Disease Control and Prevention, Kunming, Yunnan, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanling","family":"Ma","sequence":"additional","affiliation":[{"name":"Yunnan Provincial Key Laboratory of Public Health and Biosafety &amp; Institute for AIDS\/STD Control and Prevention, Yunnan Center for Disease Control and Prevention, Kunming, Yunnan, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manhong","family":"Jia","sequence":"additional","affiliation":[{"name":"Yunnan International Joint Laboratory of Public Health and Disease Control, Yunnan Center for Disease Control and Prevention, Kunming, Yunnan, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenfei","family":"Ding","sequence":"additional","affiliation":[{"name":"Yunnan International Joint Laboratory of Public Health and Disease Control, Yunnan Center for Disease Control and Prevention, Kunming, Yunnan, China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,12,29]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2024.106345"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2025.106477"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micres.2025.128229"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines13020148"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e3283522c97"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep19279"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.7448\/IAS.18.1.20035"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/455609a"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.77.1.685-695.2003"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(20)30252-6"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0065337"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0268143"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.46234\/ccdcw2024.251"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.73.1.152-160.1999"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0071131"}],"container-title":["AIDS Research and Human Retroviruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/08892229251410288","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/08892229251410288","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/08892229251410288","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:13:30Z","timestamp":1777367610000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/08892229251410288"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,29]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1177\/08892229251410288"],"URL":"https:\/\/doi.org\/10.1177\/08892229251410288","relation":{},"ISSN":["0889-2229","1931-8405"],"issn-type":[{"value":"0889-2229","type":"print"},{"value":"1931-8405","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,29]]}}}