{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T09:29:48Z","timestamp":1787131788770,"version":"build-2736575974"},"reference-count":15,"publisher":"SAGE Publications","issue":"6-7","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"crossref","award":["T32 AG000279-18"],"award-info":[{"award-number":["T32 AG000279-18"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"crossref","award":["K24 AG082527"],"award-info":[{"award-number":["K24 AG082527"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"crossref","award":["k24ai120834"],"award-info":[{"award-number":["k24ai120834"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["AIDS Research and Human Retroviruses"],"published-print":{"date-parts":[[2026,7,1]]},"abstract":"<jats:p>\n                    People aging with HIV (PAWH) experience greater impairment in physical and pulmonary function than individuals aging without HIV. We examined whether baseline physical function was associated with subsequent pulmonary impairments. Associations of frailty and physical function (gait speed [m\/s], grip strength [kg]) with pulmonary function (&lt;80% predicted diffusing capacity for carbon monoxide [DL\n                    <jats:sub>CO<\/jats:sub>\n                    ] and forced expiratory volume [FEV\n                    <jats:sub>1<\/jats:sub>\n                    ]) 3 years later were modeled; age, HIV status, and smoking were assessed as effect modifiers. Among 1,024 men (54% PAWH, 10% frail, 51% prefrail), mean (SD) age = 53 (12) years, cumulative smoking = 12 (19) pack-years, gait speed = 1.1 (0.2) m\/s, and grip strength = 36.6 (9.2) kg. Frailty, prefrailty, and weak grip strength were associated with higher odds of subsequent impaired DL\n                    <jats:sub>CO<\/jats:sub>\n                    and FEV\n                    <jats:sub>1<\/jats:sub>\n                    . Slow gait speed was associated with higher odds of DL\n                    <jats:sub>CO<\/jats:sub>\n                    impairment but not FEV\n                    <jats:sub>1<\/jats:sub>\n                    . No statistically significant modifications were found. Interventions to improve physical function may help preserve pulmonary function.\n                  <\/jats:p>","DOI":"10.1177\/08892229261448283","type":"journal-article","created":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T07:44:55Z","timestamp":1777707895000},"page":"222-226","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Frailty, Physical Function Impairment, and Pulmonary Function in Aging Men With and Without HIV from the Multicenter AIDS Cohort Study"],"prefix":"10.1177","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6992-8689","authenticated-orcid":false,"given":"Mona","family":"Abdo","sequence":"first","affiliation":[{"name":"Department of Epidemiology, Colorado School of Public Health, University of Colorado-Anschutz Medical Campus, Aurora, Colorado, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken M.","family":"Kunisaki","sequence":"additional","affiliation":[{"name":"Pulmonary Section, Minneapolis Veterans Affairs Health Care System, Minneapolis, Minnesota, USA."},{"name":"Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison","family":"Morris","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Stosor","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Chang","sequence":"additional","affiliation":[{"name":"Division of Respiratory and Critical Care Physiology and Medicine, Los Angeles Biomed Research Institute at Harbor-University of California Los Angeles Medical Center, Torrance, California, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gypsyamber","family":"D\u2019Souza","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina","family":"Crothers","sequence":"additional","affiliation":[{"name":"Veterans Affairs Puget Sound, University of Washington, Seattle, Washington, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madiha","family":"Abdel-Maksoud","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Colorado School of Public Health, University of Colorado-Anschutz Medical Campus, Aurora, Colorado, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolyn","family":"DiGuiseppi","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Colorado School of Public Health, University of Colorado-Anschutz Medical Campus, Aurora, Colorado, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd T.","family":"Brown","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Diabetes, and Metabolism, Johns Hopkins School of Medicine, Baltimore, Maryland, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha","family":"MaWhinney","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Colorado School of Public Health, Aurora, Colorado, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristine M.","family":"Erlandson","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Colorado School of Public Health, University of Colorado-Anschutz Medical Campus, Aurora, Colorado, USA."},{"name":"Division of Infectious Disease, Department of Medicine, University of Colorado-Anschutz Medical Campus, Aurora, Colorado, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,5,1]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0081355"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/56.3.M146"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11904-017-0348-x"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2018.02.014"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2022.10.005"},{"key":"e_1_3_3_7_2","unstructured":"NHLBI. MACS\/WIHS combined cohort study. 2020. Available from: https:\/\/statepi.jhsph.edu\/mwccs [Last accessed: January2 2021]."},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/126.2.310"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00034805"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00016-2016"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201710-1981ST"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1081\/COPD-200053377"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.159.1.9712108"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.153.2.8564114"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a115101"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a116813"}],"container-title":["AIDS Research and Human Retroviruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/08892229261448283","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/08892229261448283","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/08892229261448283","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T09:21:18Z","timestamp":1787131278000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/08892229261448283"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,1]]},"references-count":15,"journal-issue":{"issue":"6-7","published-print":{"date-parts":[[2026,7,1]]}},"alternative-id":["10.1177\/08892229261448283"],"URL":"https:\/\/doi.org\/10.1177\/08892229261448283","relation":{},"ISSN":["0889-2229","1931-8405"],"issn-type":[{"value":"0889-2229","type":"print"},{"value":"1931-8405","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,1]]}}}