{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T16:33:38Z","timestamp":1793205218920,"version":"4.5.0"},"reference-count":16,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Baoding Science and Technology Plan Project","award":["No.2541ZF086"],"award-info":[{"award-number":["No.2541ZF086"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["AIDS Research and Human Retroviruses"],"published-print":{"date-parts":[[2026,12,1]]},"abstract":"<jats:p>\n                    The continuous HIV-1 recombination forms circulating in China poses a persistent challenge to epidemic control. And this study identifies two novel unique recombinant forms (URFs), BDNY017 and BDK025, from antiretroviral therapy (ART)-failing patients in Hebei Province. Near full-length genomic analysis revealed that BDNY017 is a triple mosaic of CRF08_BC, CRF07_BC, and subtype B, whereas BDK025 is a dual recombinant of CRF07_BC and CRF08_BC. Genotypic resistance testing further uncovered M184V, A98G, and E138K mutations in BDNY017, while BDK025 carried no major\n                    <jats:italic toggle=\"yes\">pol-region<\/jats:italic>\n                    resistance mutations. Notably, the report of CRF08_BC-involved URFs in northern China, expanding the known geographic distribution of such recombinants beyond their traditional southwestern focus and underscoring the urgent need for enhanced molecular surveillance, particularly among ART-failing individuals, to track emerging recombinants and assess their potential impact on treatment outcomes and transmission dynamics.\n                  <\/jats:p>","DOI":"10.1177\/08892229261490627","type":"journal-article","created":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T08:08:57Z","timestamp":1790323737000},"page":"379-384","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Identification of Two Novel HIV-1 Unique Recombinant Forms Involving CRF07_BC and CRF08_BC Among ART-Failing Patients in Hebei, China"],"prefix":"10.1177","volume":"42","author":[{"given":"Haoxi","family":"Shi","sequence":"first","affiliation":[{"name":"Clinical Laboratory, The People\u2019s Hospital of Baoding, Baoding, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Meng","sequence":"additional","affiliation":[{"name":"Infection Division, The People\u2019s Hospital of Baoding, Baoding, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6727-0361","authenticated-orcid":false,"given":"Yimin","family":"Cao","sequence":"additional","affiliation":[{"name":"Medical Affairs Department, Baoding Hospital of Beijing Children\u2019s Hospital Affiliated to Capital Medical University, Baoding, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiteng","family":"Zhao","sequence":"additional","affiliation":[{"name":"Clinical Laboratory, The People\u2019s Hospital of Baoding, Baoding, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3208-3598","authenticated-orcid":false,"given":"Ying","family":"Xing","sequence":"additional","affiliation":[{"name":"Key Laboratory of Clinical Research on Respiratory and Digestive Diseases, Baoding Hospital of Beijing Children\u2019s Hospital Affiliated to Capital Medical University, Baoding, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Du","sequence":"additional","affiliation":[{"name":"Clinical Laboratory, Baoding Central Blood Station, Baoding, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shangyu","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory of Clinical Research on Respiratory and Digestive Diseases, Baoding Hospital of Beijing Children\u2019s Hospital Affiliated to Capital Medical University, Baoding, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziting","family":"Liu","sequence":"additional","affiliation":[{"name":"Clinical Laboratory, The Baoding Center for Disease Control and Prevention, Baoding, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuping","family":"Chen","sequence":"additional","affiliation":[{"name":"Key Laboratory of Clinical Research on Respiratory and Digestive Diseases, Baoding Hospital of Beijing Children\u2019s Hospital Affiliated to Capital Medical University, Baoding, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Zhao","sequence":"additional","affiliation":[{"name":"Clinical Laboratory, The People\u2019s Hospital of Baoding, Baoding, China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,9,25]]},"reference":[{"key":"e_1_3_2_2_1","unstructured":"1.UNAIDS. 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