{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T03:46:18Z","timestamp":1792813578244,"version":"4.5.0"},"reference-count":3,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2014,8,6]],"date-time":"2014-08-06T00:00:00Z","timestamp":1407283200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Hum Lact"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:p>Linezolid, a broad-spectrum antibiotic used primarily for treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections, is the first oxazolidinone approved for clinical use. This is a case report of a 30-year-old woman who was exclusively breastfeeding her infant prior to taking linezolid 600 mg orally every 12 hours to treat a MRSA mastitis. Breast milk samples were obtained over a 12-hour dosing interval on day 1 (after a single dose of therapy) and again on day 14 (at steady state). The relative infant dose at steady state was found to be 15.61% on day 14 of therapy. Using the average concentration at steady state, the estimated infant dose would have been 1.84 mg\/kg\/day, which is well below the recommended dose given to neonates requiring linezolid drug therapy. The infant did not breastfeed during maternal treatment with linezolid.<\/jats:p>","DOI":"10.1177\/0890334414546045","type":"journal-article","created":{"date-parts":[[2014,8,7]],"date-time":"2014-08-07T02:13:33Z","timestamp":1407377613000},"page":"410-412","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Transfer of Linezolid into Breast Milk"],"prefix":"10.1177","volume":"30","author":[{"given":"Hilary E.","family":"Rowe","sequence":"first","affiliation":[{"name":"Lower Mainland Pharmacy Services, Surrey Memorial Hospital, Surrey, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen","family":"Felkins","sequence":"additional","affiliation":[{"name":"School of Medicine, Texas Tech University Health Sciences Center, Amarillo, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaun D.","family":"Cooper","sequence":"additional","affiliation":[{"name":"School of Medicine, Texas Tech University Health Sciences Center, Amarillo, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas W.","family":"Hale","sequence":"additional","affiliation":[{"name":"School of Medicine, Texas Tech University Health Sciences Center, Amarillo, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2014,8,6]]},"reference":[{"key":"bibr1-0890334414546045","unstructured":"Pfizer. ZYVOX (linezolid) full prescribing information. http:\/\/labeling.pfizer.com\/showlabeling.aspx?id=649. Updated January 2014. Accessed July 22, 2014."},{"key":"bibr2-0890334414546045","doi-asserted-by":"publisher","DOI":"10.1016\/B978-044481981-9\/50025-4"},{"issue":"6","key":"bibr3-0890334414546045","first-page":"1658","volume":"92","author":"Sagirli O","year":"2009","journal-title":"J AOAC Int"}],"container-title":["Journal of Human Lactation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0890334414546045","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0890334414546045","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0890334414546045","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:30:55Z","timestamp":1777501855000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0890334414546045"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8,6]]},"references-count":3,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["10.1177\/0890334414546045"],"URL":"https:\/\/doi.org\/10.1177\/0890334414546045","relation":{},"ISSN":["0890-3344","1552-5732"],"issn-type":[{"value":"0890-3344","type":"print"},{"value":"1552-5732","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,8,6]]}}}