{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T14:57:14Z","timestamp":1785941834876,"version":"3.56.0"},"reference-count":25,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T00:00:00Z","timestamp":1785715200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Hum Lact"],"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Early pumping frequency is strongly correlated with achieving coming to volume (CTV) and having increased milk volume production. A model was created to predict CTV using early pumping frequency, achievement of early morning pumping, and birth weight.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Research Aim:<\/jats:title>\n                    <jats:p>To assess if cumulative pumping volumes during the first 5 postnatal days (CV x 5) influence coming to volume (CTV: producing &gt; 500 milliliters breast milk per day by postnatal Day 14) for mothers of hospitalized infants, with a secondary aim to develop and compare a new predictive model using CV x 5 with our previous model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A retrospective cohort analysis was conducted at a tertiary center for singleton mother\u2013baby dyads of neonatal intensive care infants between January 2020 and December 2023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Of 887 mother\u2013baby dyads, 325 (37%) achieved CTV and were more likely to have higher CV x 5 (1,058 \u00b1 25 ml vs. 231 \u00b1 19 ml;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.0001). In generalized regression models for CTV that included birth weight, five or more milk-producing pumping episodes on postnatal Day 5 (5 x 5), pumping at least once between 1 am and 5 am by postnatal Day 5 (AM x 5), and CV x 5, only CV x 5 and 5 x 5 remained significant (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.0001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Pumping frequencies and accumulating pumped volumes in the first 5 postnatal days are important factors in predicting mothers\u2019 likelihood of CTV. CTV is significantly associated with CV x 5, and, with 5 x 5, creates a stronger model than that of 5 x 5 and higher birthweight. This new model may help identify mothers needing additional support to achieve CTV as early as postnatal Day 5.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/08903344261465226","type":"journal-article","created":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T12:48:38Z","timestamp":1785761318000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Early Expressed Milk Volume and Coming to Volume for Mother\u2019s Own Milk in Hospitalized Infants"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6465-6314","authenticated-orcid":false,"given":"Nellie","family":"Chen","sequence":"first","affiliation":[{"name":"Duke University School of Medicine, Durham, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David T","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Duke University Medical Center, Durham, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamlesh","family":"Athavale","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Duke University Medical Center, Durham, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lusia","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Duke University Medical Center, Durham, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C Michael","family":"Cotten","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Duke University Medical Center, Durham, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-7394-2855","authenticated-orcid":false,"given":"Keyaria D","family":"Gray","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Duke University Medical Center, Durham, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,8,3]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"crossref","unstructured":"Bendixen M. M. Iapicca L. C. Parker L. A. (2023). Nonpharmacologic factors affecting milk production in pump-dependent mothers of critically ill infants: State of the science. Advances in Neonatal Care 23(1) 51\u201363. https:\/\/doi.org\/10.1097\/anc.0000000000000990","DOI":"10.1097\/ANC.0000000000000990"},{"key":"e_1_3_3_3_1","doi-asserted-by":"crossref","unstructured":"Boies E. G. Vaucher Y. E. (2016). ABM clinical protocol #10: Breastfeeding the late preterm (34-36 6\/7 weeks of gestation) and early term infants (37-38 6\/7 weeks of gestation) second revision 2016. Breastfeeding Medicine 11 494\u2013500. https:\/\/doi.org\/10.1089\/bfm.2016.29031.egb","DOI":"10.1089\/bfm.2016.29031.egb"},{"key":"e_1_3_3_4_1","doi-asserted-by":"crossref","unstructured":"Chen D. C. Nommsen-Rivers L. Dewey K. G. L\u00f6nnerdal B. (1998). Stress during labor and delivery and early lactation performance. The American Journal of Clinical Nutrition 68(2) 335\u2013344. https:\/\/doi.org\/10.1093\/ajcn\/68.2.335","DOI":"10.1093\/ajcn\/68.2.335"},{"key":"e_1_3_3_5_1","doi-asserted-by":"crossref","unstructured":"Chen D. C. Nommsen-Rivers L. Dewey K. G. L\u00f6nnerdal B. (2017). Committee opinion no. 712: Intrapartum management of intraamniotic infection. Obstetrics & Gynecology 130(2) e95\u2013e101. https:\/\/doi.org\/10.1097\/aog.0000000000002236","DOI":"10.1097\/AOG.0000000000002236"},{"key":"e_1_3_3_6_1","doi-asserted-by":"crossref","unstructured":"Cordero L. Stenger M. R. Landon M. B. Nankervis C. A. (2022). Exclusive breastfeeding among women with type 1 and type 2 diabetes mellitus. BMC Pregnancy Childbirth 22(1) 69. https:\/\/doi.org\/10.1186\/s12884-022-04411-w","DOI":"10.1186\/s12884-022-04411-w"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.2307\/2531595"},{"key":"e_1_3_3_8_1","doi-asserted-by":"crossref","unstructured":"Dewey K. G. (2001). Maternal and fetal stress are associated with impaired lactogenesis in humans. The Journal of Nutrition 131(11) 3012s\u20133015s. https:\/\/doi.org\/10.1093\/jn\/131.11.3012S","DOI":"10.1093\/jn\/131.11.3012S"},{"key":"e_1_3_3_9_1","doi-asserted-by":"crossref","unstructured":"Fewtrell M. S. Kennedy K. Ahluwalia J. S. Nicholl R. Lucas A. Burton P. (2016). Predictors of expressed breast milk volume in mothers expressing milk for their preterm infant. Archives of Disease in Childhood\u2013Fetal and Neonatal Edition 101(6) F502\u2013F506. https:\/\/doi.org\/10.1136\/archdischild-2015-308321","DOI":"10.1136\/archdischild-2015-308321"},{"key":"e_1_3_3_10_1","doi-asserted-by":"crossref","unstructured":"Hoban R. Bigger H. Schoeny M. Engstrom J. Meier P. Patel A. L. (2018). Milk volume at 2 weeks predicts mother's own milk feeding at neonatal intensive care unit discharge for very low birthweight infants. Breastfeeding Medicine 13(2) 135\u2013141. https:\/\/doi.org\/10.1089\/bfm.2017.0159","DOI":"10.1089\/bfm.2017.0159"},{"key":"e_1_3_3_11_1","doi-asserted-by":"crossref","unstructured":"Hoban R. Bowker R. M. Gross M. E. Patel A. L. (2021). Maternal production of milk for infants in the neonatal intensive care unit. Seminars in Perinatology 45(2) Article 151381. https:\/\/doi.org\/https:\/\/doi.org\/10.1016\/j.semperi.2020.151381","DOI":"10.1016\/j.semperi.2020.151381"},{"key":"e_1_3_3_12_1","doi-asserted-by":"crossref","unstructured":"Hoban R. Medina-Poeliniz C. Signorile M. Janes J. Fan C.-P. S. Meier P. P. (2024). Early postpartum pumping behaviors pumped milk volume and achievement of secretory activation in breast pump-dependent mothers of preterm infants. Journal of Perinatology 44 1597\u20131606. https:\/\/doi.org\/10.1038\/s41372-024-02021-2","DOI":"10.1038\/s41372-024-02021-2"},{"key":"e_1_3_3_13_1","doi-asserted-by":"crossref","unstructured":"Hytten F. E. (1954). Clinical and chemical studies in human lactation. VIII. Relationship of the age physique and nutritional status of the mother to the yield and composition of her milk. British Medical Journal 2(4892) 844\u2013845. https:\/\/doi.org\/10.1136\/bmj.2.4892.844","DOI":"10.1136\/bmj.2.4892.844"},{"key":"e_1_3_3_14_1","doi-asserted-by":"crossref","unstructured":"Mago-Shah D. D. Athavale K. Fisher K. Heyward E. Tanaka D. Cotten C. M. (2023). Early pumping frequency and coming to volume for mother\u2019s own milk feeding in hospitalized infants. Journal of Perinatology 43(5) 629\u2013634. https:\/\/doi.org\/10.1038\/s41372-023-01662-z","DOI":"10.1038\/s41372-023-01662-z"},{"key":"e_1_3_3_15_1","doi-asserted-by":"crossref","unstructured":"Medina Poeliniz C. Hoban R. Janes J. Meier P. P. (2025). Pumping behaviors of breast pump-dependent mothers of preterm infants in the Neonatal Intensive Care Unit (NICU): Importance of the first five postpartum days. Breastfeeding Medicine 20(7) 493\u2013501. https:\/\/doi.org\/10.1089\/bfm.2024.0396","DOI":"10.1089\/bfm.2024.0396"},{"key":"e_1_3_3_16_1","doi-asserted-by":"crossref","unstructured":"Moberg K. U. Ekstr\u00f6m-Bergstr\u00f6m A. Buckley S. Massarotti C. Pajalic Z. Luegmair K. Kotlowska A. Lengler L. Olza I. Grylka-Baeschlin S. (2020). Maternal plasma levels of oxytocin during breastfeeding\u2014A systematic review. PLoS One 15 Article e0235806. https:\/\/doi.org\/10.1371\/journal.pone.0235806","DOI":"10.1371\/journal.pone.0235806"},{"key":"e_1_3_3_17_1","doi-asserted-by":"crossref","unstructured":"Murase M. Nommsen-Rivers L. Morrow A. L. Hatsuno M. Mizuno K. Taki M. Miyazawa T. Nakano Y. Aizawa M. Itabashi K. (2014). Predictors of low milk volume among mothers who delivered preterm. Journal of Human Lactation 30(4) 425\u2013435. https:\/\/doi.org\/10.1177\/0890334414543951","DOI":"10.1177\/0890334414543951"},{"key":"e_1_3_3_18_1","doi-asserted-by":"crossref","unstructured":"Neville M. C. Morton J. Umemura S. (2001). Lactogenesis: The transition from pregnancy to lactation. Pediatric Clinics of North America 48(1) 35\u201352. https:\/\/doi.org\/10.1016\/s0031-3955(05)70284-4","DOI":"10.1016\/S0031-3955(05)70284-4"},{"key":"e_1_3_3_19_1","doi-asserted-by":"crossref","unstructured":"Parker L. A. Sullivan S. Krueger C. Mueller M. (2015). Association of timing of initiation of breastmilk expression on milk volume and timing of lactogenesis stage II among mothers of very low-birth-weight infants. Breastfeeding Medicine 10(2) 84\u201391. https:\/\/doi.org\/10.1089\/bfm.2014.0089","DOI":"10.1089\/bfm.2014.0089"},{"key":"e_1_3_3_20_1","doi-asserted-by":"crossref","unstructured":"Parker M. G. Gupta M. Melvin P. Burnham L. A. Lopera A. M. Moses J. M. Litt J. S. Belfort M. B. (2019). Racial and ethnic disparities in the use of mother's milk feeding for very low birth weight infants in Massachusetts. The Journal of Pediatrics 204 134\u2013141 Article e131. https:\/\/doi.org\/10.1016\/j.jpeds.2018.08.036","DOI":"10.1016\/j.jpeds.2018.08.036"},{"key":"e_1_3_3_21_1","doi-asserted-by":"crossref","unstructured":"Parker M. G. Melvin P. Graham D. A. Gupta M. Burnham L. A. Lopera A. M. Zera C. A. Belfort M. B. (2019). Timing of first milk expression to maximize breastfeeding continuation among mothers of very low-birth-weight infants. Obstetrics & Gynecology 133(6) 1208\u20131215. https:\/\/doi.org\/10.1097\/aog.0000000000003258","DOI":"10.1097\/AOG.0000000000003258"},{"key":"e_1_3_3_22_1","doi-asserted-by":"crossref","unstructured":"Parker M. G. Stellwagen L. M. Noble L. Kim J. H. Poindexter B. B. Puopolo K. M. Section on Breastfeeding Committee on Nutrition Committee on Fetus & Newborn. (2021). Promoting human milk and breastfeeding for the very low birth weight infant. Pediatrics 148(5) Article e2021054272. https:\/\/doi.org\/10.1542\/peds.2021-054272","DOI":"10.1542\/peds.2021-054272"},{"key":"e_1_3_3_23_1","doi-asserted-by":"crossref","unstructured":"Sankar M. N. Weiner Y. E. Chopra N. Kan P. Williams Z. Lee H. C. (2022). Barriers to optimal breast milk provision in the neonatal intensive care unit. Journal of Perinatology 42(8) 1076\u20131082. https:\/\/doi.org\/10.1038\/s41372-021-01275-4","DOI":"10.1038\/s41372-021-01275-4"},{"key":"e_1_3_3_24_1","doi-asserted-by":"crossref","unstructured":"Schwarz G. (1978). Estimating the dimension of a model. The Annals of Statistics 6(2) 461\u2013464 464. https:\/\/doi.org\/10.1214\/aos\/1176344136","DOI":"10.1214\/aos\/1176344136"},{"key":"e_1_3_3_25_1","doi-asserted-by":"crossref","unstructured":"Stone J. Warren R. M. L. Pinney E. Warwick J. Cuzick J. (2009). Determinants of percentage and area measures of mammographic density. American Journal of Epidemiology 170(12) 1571\u20131578. https:\/\/doi.org\/10.1093\/aje\/kwp313","DOI":"10.1093\/aje\/kwp313"},{"key":"e_1_3_3_26_1","doi-asserted-by":"crossref","unstructured":"Urminsky O. Hansen C. Chernozhukov V. (2016). Using double-lasso regression for principled variable selection. https:\/\/ssrn.com\/abstract=2733374","DOI":"10.2139\/ssrn.2733374"}],"container-title":["Journal of Human Lactation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/08903344261465226","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/08903344261465226","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/08903344261465226","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T14:19:51Z","timestamp":1785939591000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/08903344261465226"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,3]]},"references-count":25,"alternative-id":["10.1177\/08903344261465226"],"URL":"https:\/\/doi.org\/10.1177\/08903344261465226","relation":{},"ISSN":["0890-3344","1552-5732"],"issn-type":[{"value":"0890-3344","type":"print"},{"value":"1552-5732","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,3]]},"article-number":"08903344261465226"}}