{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T17:32:15Z","timestamp":1786642335001,"version":"build-2736575974"},"reference-count":37,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T00:00:00Z","timestamp":1786320000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Hum Lact"],"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Human milk banks play a critical role in neonatal care by providing donor human milk when maternal milk is unavailable, particularly for preterm and medically vulnerable infants. Despite global expansion, long-term evaluations of discard rates and quality indicators remain limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Research Aim:<\/jats:title>\n                    <jats:p>To assess discard rates due to nonconformities, temporal trends in quality indicators, and nutritional characteristics of donor human milk processed in a tertiary-care milk bank over a 10-year period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This retrospective longitudinal study analyzed routinely collected data from a Brazilian tertiary-care human milk bank between January 2014 and December 2023. Outcomes included collected and pasteurized milk volumes, and discard reasons: labeling, storage, packaging, physical contaminants, acidity \u2265 8\u00b0D, and microbiological positivity (BGBL+). Nutritional quality was evaluated using crematocrit-derived caloric classification. Temporal trends were examined using linear regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Over the study period, 11,758.2\u2009L of milk were collected and 7,851\u2009L pasteurized. A total of 387.2\u2009L (3.3%) was discarded due to nonconformities. Storage-related issues accounted for most losses (56.2%), followed by microbiological positivity (21.9%). Overall, discard rates remained low and stable (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u2009.924). Labeling errors declined (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u2009.044), while physical contaminants (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u2009.001) and microbiological positivity increased (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u2009.032). Dornic acidity exceeded thresholds in only 0.04% of samples. Among 47,919 pasteurized bottles, caloric composition remained stable: 54.7% normocaloric, 39.7% hypercaloric, 5.6% hypocaloric.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Standardized quality-control procedures were associated with consistently low discard rates and stable nutritional quality. Improving cold-chain logistics and microbiological monitoring may further reduce losses and enhance donor milk availability.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/08903344261470648","type":"journal-article","created":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T11:49:38Z","timestamp":1786362578000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Ten-Year Evaluation of Quality Control Indicators in a Brazilian Human Milk Bank"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-4705-0160","authenticated-orcid":false,"given":"Renata","family":"Venturim","sequence":"first","affiliation":[{"name":"Department of Pediatrics, School of Medical Sciences, State University of Campinas (Unicamp), Campinas, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00f4nica Aparecida","family":"Pessoto","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, School of Medical Sciences, State University of Campinas (Unicamp), Campinas, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,8,10]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"crossref","unstructured":"Almeida S. 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Universidade Federal de Uberl\u00e2ndia Institutional Repository. https:\/\/repositorio.ufu.br\/handle\/123456789\/18050. https:\/\/doi.org\/10.14393\/ufu.di.2016.467","DOI":"10.14393\/ufu.di.2016.467"},{"key":"e_1_3_3_5_1","doi-asserted-by":"crossref","unstructured":"Borges M. S. Oliveira A. M. M. Hattori W. T. Abdallah V. O. S. (2018). Quality of human milk expressed in a human milk bank and at home. Jornal de Pediatria 94(4) 399\u2013403. https:\/\/doi.org\/10.1016\/j.jped.2017.07.004","DOI":"10.1016\/j.jped.2017.07.004"},{"key":"e_1_3_3_6_1","unstructured":"Brasil. Ag\u00eancia Nacional de Vigil\u00e2ncia Sanit\u00e1ria. (2008). Banco de leite humano: Funcionamento preven\u00e7\u00e3o e controle de riscos [Human milk bank: Operation prevention and risk control]. Ag\u00eancia Nacional de Vigil\u00e2ncia Sanit\u00e1ria. https:\/\/bibliotecadigital.anvisa.gov.br\/jspui\/handle\/anvisa\/1546"},{"key":"e_1_3_3_7_1","unstructured":"Brasil. Minist\u00e9rio da Sa\u00fade. (2021a). 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