{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T23:32:24Z","timestamp":1777851144952,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2002,9,1]],"date-time":"2002-09-01T00:00:00Z","timestamp":1030838400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Geriatr Psychiatry Neurol"],"published-print":{"date-parts":[[2002,9]]},"abstract":"<jats:p>Agitation is one of the most troublesome behaviors in demented patients. It is etiologically heterogeneous and has varied associated behaviors. To explore the transcultural differences in the manifestation of agitation, we evaluated 50 consecutive Alzheimer's disease (AD) patients in three countries (Taiwan, Italy, and the United States) using the Neuropsychiatric Inventory (NPI) and the Mini-Mental State Examination (MMSE). In a focused analysis, only patients with composite NPI scores &gt; 2 for agitation were selected, with similar levels of disease severity as measured by the MMSE, from the three groups (n = 15 per group) to evaluate culturally specific correlates of agitation. Agitated Taiwanese had significantly more hallucinations than either Italian or American patients. Agitated Italian patients had significantly more apathy than both Taiwanese and American patients. Cultural factors may influence the manifestation of agitation more than a common underlying neuropathology. Management strategies targeting unique behavioral instigators of agitation may be specific for different ethnic groups.<\/jats:p>","DOI":"10.1177\/089198870201500308","type":"journal-article","created":{"date-parts":[[2014,3,18]],"date-time":"2014-03-18T19:53:51Z","timestamp":1395172431000},"page":"171-174","source":"Crossref","is-referenced-by-count":11,"title":["A Transcultural Study of Agitation in Dementia"],"prefix":"10.1177","volume":"15","author":[{"given":"Jong-Ling","family":"Fuh","sequence":"first","affiliation":[{"name":"Neurological Institute (Drs. Fuh and Wang), Taipei Veterans General Hospital and National Yang-Ming University Schools of Medicine, Taipei, Taiwan; Laboratory of Neuro Imaging (Dr. Mega), Alzheimer's Disease Center (Drs. Mega and Cummings), and Department of Psychiatry and Biobehavioral Science (Dr. Cummings), UCLA School of Medicine, Los Angeles, California; Neurobiology Laboratory (Dr. Binetti), Alzheimer's Disease Unit, IRCCS S.Giovanni di Dio Fatebenefratelli, Brescia, Italy; and the Neurology..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. S.","family":"Mega","sequence":"additional","affiliation":[{"name":"Neurological Institute (Drs. Fuh and Wang), Taipei Veterans General Hospital and National Yang-Ming University Schools of Medicine, Taipei, Taiwan; Laboratory of Neuro Imaging (Dr. Mega), Alzheimer's Disease Center (Drs. Mega and Cummings), and Department of Psychiatry and Biobehavioral Science (Dr. Cummings), UCLA School of Medicine, Los Angeles, California; Neurobiology Laboratory (Dr. Binetti), Alzheimer's Disease Unit, IRCCS S.Giovanni di Dio Fatebenefratelli, Brescia, Italy; and the Neurology..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Binetti","sequence":"additional","affiliation":[{"name":"Neurological Institute (Drs. Fuh and Wang), Taipei Veterans General Hospital and National Yang-Ming University Schools of Medicine, Taipei, Taiwan; Laboratory of Neuro Imaging (Dr. Mega), Alzheimer's Disease Center (Drs. Mega and Cummings), and Department of Psychiatry and Biobehavioral Science (Dr. Cummings), UCLA School of Medicine, Los Angeles, California; Neurobiology Laboratory (Dr. Binetti), Alzheimer's Disease Unit, IRCCS S.Giovanni di Dio Fatebenefratelli, Brescia, Italy; and the Neurology..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. J.","family":"Wang","sequence":"additional","affiliation":[{"name":"Neurological Institute (Drs. Fuh and Wang), Taipei Veterans General Hospital and National Yang-Ming University Schools of Medicine, Taipei, Taiwan; Laboratory of Neuro Imaging (Dr. Mega), Alzheimer's Disease Center (Drs. Mega and Cummings), and Department of Psychiatry and Biobehavioral Science (Dr. Cummings), UCLA School of Medicine, Los Angeles, California; Neurobiology Laboratory (Dr. Binetti), Alzheimer's Disease Unit, IRCCS S.Giovanni di Dio Fatebenefratelli, Brescia, Italy; and the Neurology..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Magni","sequence":"additional","affiliation":[{"name":"Neurological Institute (Drs. Fuh and Wang), Taipei Veterans General Hospital and National Yang-Ming University Schools of Medicine, Taipei, Taiwan; Laboratory of Neuro Imaging (Dr. Mega), Alzheimer's Disease Center (Drs. Mega and Cummings), and Department of Psychiatry and Biobehavioral Science (Dr. Cummings), UCLA School of Medicine, Los Angeles, California; Neurobiology Laboratory (Dr. Binetti), Alzheimer's Disease Unit, IRCCS S.Giovanni di Dio Fatebenefratelli, Brescia, Italy; and the Neurology..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. L.","family":"Cummings","sequence":"additional","affiliation":[{"name":"Neurological Institute (Drs. Fuh and Wang), Taipei Veterans General Hospital and National Yang-Ming University Schools of Medicine, Taipei, Taiwan; Laboratory of Neuro Imaging (Dr. Mega), Alzheimer's Disease Center (Drs. Mega and Cummings), and Department of Psychiatry and Biobehavioral Science (Dr. Cummings), UCLA School of Medicine, Los Angeles, California; Neurobiology Laboratory (Dr. Binetti), Alzheimer's Disease Unit, IRCCS S.Giovanni di Dio Fatebenefratelli, Brescia, Italy; and the Neurology..."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2002,9,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.157.1.86"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1988.tb03427.x"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1988.tb03426.x"},{"key":"atypb4","first-page":"101","volume":"19","author":"Cohen-Mansfield J.","year":"1989","journal-title":"Issues Geriatr Psychiatry"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.44.12.2308"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.147.8.1049"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1017\/S1041610299005736"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1037\/0882-7974.7.4.622"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.34.7.939"},{"key":"atypb10","volume-title":"Dementia: a clinical approach","author":"Cummings JL","year":"1992","edition":"2"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3956(75)90026-6"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1126\/science.253.5018.390"},{"key":"atypb13","volume-title":"Computer intensive statistical methods","author":"Hjorth JSU.","year":"1994"},{"key":"atypb14","volume-title":"Permutation tests\u2014a practical guide to resampling methods for testing hypotheses","author":"Good P.","year":"1994"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.55.4.539"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.156.1.66"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/54.3.M157"},{"issue":"7","key":"atypb18","first-page":"55","volume":"57","author":"Mintzer JE","year":"1996","journal-title":"J Clin Psychiatry"},{"issue":"3","key":"atypb19","first-page":"487","volume":"8","author":"Mintzer JE","year":"1996","journal-title":"Int Psychogeriatr"},{"key":"atypb20","first-page":"61","volume":"52","author":"Golden RN","year":"1991","journal-title":"J Clin Psychiatry"},{"key":"atypb21","doi-asserted-by":"publisher","DOI":"10.1177\/070674378402900313"},{"key":"atypb22","doi-asserted-by":"publisher","DOI":"10.1006\/brcg.1995.1255"},{"key":"atypb23","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1991.tb00217.x"},{"key":"atypb24","doi-asserted-by":"publisher","DOI":"10.1017\/S1041610201007517"}],"container-title":["Journal of Geriatric Psychiatry and Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/089198870201500308","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/089198870201500308","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:17:25Z","timestamp":1777501045000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/089198870201500308"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,9]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2002,9]]}},"alternative-id":["10.1177\/089198870201500308"],"URL":"https:\/\/doi.org\/10.1177\/089198870201500308","relation":{},"ISSN":["0891-9887","1552-5708"],"issn-type":[{"value":"0891-9887","type":"print"},{"value":"1552-5708","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,9]]}}}