{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T23:32:55Z","timestamp":1777851175189,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2005,3,1]],"date-time":"2005-03-01T00:00:00Z","timestamp":1109635200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Geriatr Psychiatry Neurol"],"published-print":{"date-parts":[[2005,3]]},"abstract":"<jats:p>\n                    Cobalamin deficiency may cause cognitive deficits and even dementia. In Alzheimer\u2019s disease, the most frequent cause of dementia in elderly persons, low serum levels of vitamin B\n                    <jats:sub>12<\/jats:sub>\n                    , may be misleading. The aim of this work was to characterize the cognitive pattern of B\n                    <jats:sub>12<\/jats:sub>\n                    deficiency and to compare it with that of Alzheimer\u2019s disease. Nineteen patients with low levels of vitamin B\n                    <jats:sub>12<\/jats:sub>\n                    were neuropsychologically evaluated before treatment and a year later. Results were compared with those of 10 healthy control subjects. Final results suggest that there is a different pattern in both diseases. Twelve elderly patients with dementia improved with treatment. Seven elderly demented patients did not improve; they deteriorated after 1 year although their levels of cobalamin were normal. Analysis of the initial evaluation showed that the 2 groups of patients had a different neuropsychological profile. The group that improved had initially more psychotic problems and more deficits in concentration, visuospatial performance, and executive functions. They did not show language problems and ideomotor apraxia, which were present in the second group. Their memory pattern was also different. These findings suggest that cobalamin deficiency may cause a reversible dementia in elderly patients. This dementia may be differentiated from that of Alzheimer\u2019s disease by a thorough neuropsychological evaluation. ( J Geriatr Psychiatry Neurol 2005; 18:33-38)\n                  <\/jats:p>","DOI":"10.1177\/0891988704272308","type":"journal-article","created":{"date-parts":[[2005,1,28]],"date-time":"2005-01-28T13:53:43Z","timestamp":1106920423000},"page":"33-38","source":"Crossref","is-referenced-by-count":38,"title":["Neuropsychology of Vitamin B\u2081\u2082 Deficiency in Elderly Dementia Patients and Control Subjects"],"prefix":"10.1177","volume":"18","author":[{"given":"Alicia","family":"Osimani","sequence":"first","affiliation":[{"name":"Kaplan Hospital, Rehovot, Israel and the Department of Behavioral Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Berger","sequence":"additional","affiliation":[{"name":"Department of Behavioral Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua","family":"Friedman","sequence":"additional","affiliation":[{"name":"Kaplan Hospital, Rehovot, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bat-Sheba","family":"Porat-Katz","sequence":"additional","affiliation":[{"name":"Kaplan Hospital, Rehovot, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob M.","family":"Abarbanel","sequence":"additional","affiliation":[{"name":"Kaplan Hospital, Rehovot, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2005,3,1]]},"reference":[{"key":"atypb1","first-page":"223","volume-title":"Handbook of Clinical Neurology: Systemic Disease, Part II","author":"Abarbanel JM","year":"1989"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V72.3.940.bloodjournal723940"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/85.1.32"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1991.tb03566.x"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.55.11.1449"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1994.tb04939.x"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM194407062310101"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/63.3.306"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/65.1.20"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1983.03330450047024"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1207\/S15326942DN2003_1"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1002\/1097-4679(199311)49:6<883::AID-JCLP2270490616>3.0.CO;2-6"},{"key":"atypb13","first-page":"205","volume":"30","author":"Osterrieth PA","year":"1945","journal-title":"Arch Psychol"},{"key":"atypb14","volume-title":"Boston Naming Test","author":"Kaplan E","year":"1983"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1037\/h0054651"},{"key":"atypb16","volume-title":"Wisconsin Card Sorting Test Manual","author":"Heaton RK","year":"1981"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1016\/0376-8716(82)90017-5"},{"key":"atypb18","volume-title":"Wechsler Adult Intelligence Scale (Revised)","author":"Wechsler DA","year":"1981"},{"key":"atypb19","volume-title":"The Assessment of Aphasia and Related Disorders","author":"Goodglass H","year":"1983"}],"container-title":["Journal of Geriatric Psychiatry and Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0891988704272308","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0891988704272308","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:17:51Z","timestamp":1777501071000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0891988704272308"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,3]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,3]]}},"alternative-id":["10.1177\/0891988704272308"],"URL":"https:\/\/doi.org\/10.1177\/0891988704272308","relation":{},"ISSN":["0891-9887","1552-5708"],"issn-type":[{"value":"0891-9887","type":"print"},{"value":"1552-5708","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,3]]}}}