{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T23:34:03Z","timestamp":1777851243801,"version":"3.51.4"},"reference-count":36,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2009,12,8]],"date-time":"2009-12-08T00:00:00Z","timestamp":1260230400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Geriatr Psychiatry Neurol"],"published-print":{"date-parts":[[2010,3]]},"abstract":"<jats:p>In Parkinson disease (PD), cognitive impairment is common, occurs mainly in the form of milder deficits (as opposed to dementia), and commonly coincides with depression. In this cross-sectional study, we evaluated whether depression that existed before the onset of typical motor symptoms (pre-PD depression) reflected on the actual cognitive performance. Nondemented nonpsychotic PD patients with (test, n = 27) and without (control, n = 112) a history of pre-PD depression, caliper-matched for age, education, and disease duration were assessed for motor and nonmotor disease characteristics and in a battery of cognitive tests. Test patients had higher actual depression\/anxiety levels. Gradual multivariate and mediation analysis indicated unfavorable effects of pre-PD depression on cognition: a direct effect on mental set shifting\/response inhibition (independent of actual depression\/ anxiety or other factors); and indirect effects on other cognitive domains mediated through the increased depression\/anxiety. Data suggest that pre-PD depression favors poorer cognitive abilities in nondemented patients at a given time after PD has been diagnosed.<\/jats:p>","DOI":"10.1177\/0891988709351831","type":"journal-article","created":{"date-parts":[[2009,12,8]],"date-time":"2009-12-08T23:45:08Z","timestamp":1260315908000},"page":"15-26","source":"Crossref","is-referenced-by-count":17,"title":["Cognitive Performance in Nondemented Nonpsychotic Parkinson Disease Patients With or Without a History of Depression Prior to the Onset of Motor Symptoms"],"prefix":"10.1177","volume":"23","author":[{"given":"Nata\u0161a","family":"Klepac","sequence":"first","affiliation":[{"name":"Department of Neurology, University Hospital Centre Zagreb, Zagreb University School of Medicine, Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanja","family":"Hajn\u0161ek","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Hospital Centre Zagreb, Zagreb University School of Medicine, Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir","family":"Trkulja","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Zagreb University School of Medicine, Zagreb, Croatia,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2009,12,8]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(06)70373-8"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(03)00351-X"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1002\/mds.10010"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2317"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/112.5.1141"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.53.7.597"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.55.5.377"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1097\/WNN.0b013e3181799da6"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.60.3.387"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20216"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.64.2.178"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/106.2.257"},{"issue":"7","key":"atypb13","first-page":"575","volume":"13","author":"Cahn DA","year":"1998","journal-title":"Arch Clin Neuropsychol"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2007.02011.x"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.2006.00579.x"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.51.6.745"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1993.03500180078038"},{"key":"atypb18","unstructured":"Fahn S., Elton RL Members of the UPDRS development committee unified Parkinson\u2019s disease rating scale. In: Fahn S, et al., eds. Recent Developments in Parkinson\u2019s Disease, Vol. 2 . New York: MacMillan; 1987:153-163."},{"key":"atypb19","volume-title":"Stroop Color and Word Test","author":"Golden CJ","year":"1978"},{"key":"atypb20","volume-title":"Wechsler Adult Intelligence Scale Revise (WAIS-R): Test Manual","author":"Wechsler D.","year":"1981"},{"key":"atypb21","volume-title":"Multilingual Aphasia Examination","author":"Benton A.","year":"1983","edition":"3"},{"key":"atypb22","volume-title":"Test: Manual","author":"Smith A.","year":"1991"},{"key":"atypb23","volume-title":"Learning Test: A Handbook","author":"Schmidt M.","year":"1996"},{"key":"atypb24","volume-title":"Neuropsychological Assessment","author":"Lezak MD","year":"1983","edition":"2"},{"key":"atypb25","volume-title":"Manual for Administration and Scoring. South","author":"Reitan RM","year":"1992"},{"key":"atypb26","volume-title":"Neuropsychological Assessment","author":"Lezak MD","year":"1995","edition":"3"},{"key":"atypb27","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2007.06040690"},{"key":"atypb28","doi-asserted-by":"publisher","DOI":"10.3758\/BRM.40.3.879"},{"key":"atypb29","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20792"},{"key":"atypb30","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2008.02299.x"},{"key":"atypb31","doi-asserted-by":"publisher","DOI":"10.1016\/S0149-7634(99)00067-6"},{"key":"atypb32","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2005.03.008"},{"key":"atypb33","doi-asserted-by":"publisher","DOI":"10.1023\/A:1026595011371"},{"key":"atypb34","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.157.12.1949"},{"key":"atypb35","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3956(02)00085-7"},{"key":"atypb36","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.106.025064"}],"container-title":["Journal of Geriatric Psychiatry and Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0891988709351831","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0891988709351831","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:18:45Z","timestamp":1777501125000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0891988709351831"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12,8]]},"references-count":36,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,3]]}},"alternative-id":["10.1177\/0891988709351831"],"URL":"https:\/\/doi.org\/10.1177\/0891988709351831","relation":{},"ISSN":["0891-9887","1552-5708"],"issn-type":[{"value":"0891-9887","type":"print"},{"value":"1552-5708","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,12,8]]}}}