{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T11:02:46Z","timestamp":1789124566376,"version":"build-2803163510"},"reference-count":38,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2022,10,22]],"date-time":"2022-10-22T00:00:00Z","timestamp":1666396800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Geriatr Psychiatry Neurol"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Depressive disorders (DD) are widely recognized as one of the most frequent neuropsychiatric disorders in Parkinson\u00b4s disease. Patients with late-stage Parkinson\u00b4s disease (LSPD) continue to be a neglected population, and little is known about DD frequency in LSPD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To determine the frequency of DD in LSPD patients through a clinical diagnostic interview (CDI) and according to diagnostic DSM- 5 criteria. Secondary objectives were to determine the predictive ability of depressive scales to detect DD, to identify potential predictors of DD in LSPD and, to evaluate suicidal phenomena in LSPD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross-sectional study including LSPD patients (\u22657\u00a0years from symptom onset and Hoehn and Yahr scale score &gt;3 or a Schwab and England scale score &lt;50% in the ON condition) was conducted. Patients were subjected to psychiatric, neurological, and neuropsychological evaluations. Six depression scales were applied.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>92 LSPD patients were included. 59.78% of LSPD patients had a current diagnosis of DD according to CDI, 38.04% patients had a diagnosis of major depressive disorder, and 21.72% non-major depressive disorder. Suicidal ideation was present in 36.96% of patients. All applied scales were able to detect depressive disorders.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>More than half of LSPD patients met DD diagnostic criteria and over one-third were diagnosed with major depressive disorder. Overall, the LSPD population seem to have a unique clinical phenotype regarding the frequency and features of DD, whose early identification and treatment could improve the quality of life of patients and caregivers.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/08919887221135556","type":"journal-article","created":{"date-parts":[[2022,10,22]],"date-time":"2022-10-22T04:28:09Z","timestamp":1666412889000},"page":"336-346","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["High frequency of Depressive Disorders and Suicidal Phenomena in Late-Stage Parkinson\u00b4s Disease \u2013 A Cross-Sectional Study"],"prefix":"10.1177","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0722-730X","authenticated-orcid":false,"given":"In\u00eas","family":"Chendo","sequence":"first","affiliation":[{"name":"Psychiatry Department, Department of Neurosciences, Hospital de Santa Maria, Lisbon, Portugal"},{"name":"Cl\u00ednica Universit\u00e1ria de Psiquiatria e Psicologia M\u00e9dica, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal"},{"name":"CNS \u2013 Campus Neurol\u00f3gico, Torres Vedras, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margherita","family":"Fabbri","sequence":"additional","affiliation":[{"name":"Instituto de Medicina Molecular Jo\u00e3o Lobo Antunes, Lisbon, Portugal"},{"name":"Department of Neurosciences, Clinical Investigation Center CIC 1436, Parkinson Toulouse Expert Center, NS-Park\/FCRIN Network and NeuroToul COEN Center, Toulouse University Hospital, INSERM, University of Toulouse 3, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2304-3129","authenticated-orcid":false,"given":"Catarina","family":"Godinho","sequence":"additional","affiliation":[{"name":"Grupo de Patologia M\u00e9dica, Nutri\u00e7\u00e3o e Exerc\u00edcio Cl\u00ednico (PaMNEC) 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