{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T23:32:02Z","timestamp":1777851122571,"version":"3.51.4"},"reference-count":48,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2024,12,23]],"date-time":"2024-12-23T00:00:00Z","timestamp":1734912000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100001736","name":"German-Israeli Foundation for Scientific Research and Development","doi-asserted-by":"publisher","award":["1157\/20"],"award-info":[{"award-number":["1157\/20"]}],"id":[{"id":"10.13039\/501100001736","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006544","name":"Ministry of Health, State of Israel","doi-asserted-by":"publisher","award":["3-9542"],"award-info":[{"award-number":["3-9542"]}],"id":[{"id":"10.13039\/501100006544","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Geriatr Psychiatry Neurol"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:p>Switching, a critical executive function, can manifest as task switching (TS) or response switching (RS). Although TS impairments in Parkinson\u2019s disease (PD) are well-studied, RS, especially in contexts requiring adaptive behavior to external or internal cues, is less explored. This study evaluated the impact of PD on RS under exogenous and endogenous cueing. Using a gamified, remote task triggering these cues, RS was assessed in 85 PD patients and 82 neurologically healthy participants (NHP). RS cost was quantified by comparing reaction times between repeating and changing responses. A linear mixed model analyzed the effects of group, cueing mode, and their interaction on RS cost. PD patients exhibited increased RS costs under exogenous cueing but not under endogenous cueing. These findings indicate that while PD patients can effectively use predictive endogenous cues, they struggle with less predictive exogenous cues, emphasizing the need for compensatory strategies and technological aids in daily activities.<\/jats:p>","DOI":"10.1177\/08919887241311170","type":"journal-article","created":{"date-parts":[[2024,12,23]],"date-time":"2024-12-23T08:55:57Z","timestamp":1734944157000},"page":"295-302","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Alterations in Response Switching in Parkinson\u2019s Disease: New Insights Into Cueing"],"prefix":"10.1177","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-0189-2705","authenticated-orcid":false,"given":"Ori","family":"Peleg","sequence":"first","affiliation":[{"name":"Laboratory for Early Markers of Neurodegeneration (LEMON), Center for the Study of Movement, Cognition, and Mobility (CMCM), Tel Aviv Sourasky Medical Center, Neurological Institute, Tel Aviv, Israel"},{"name":"Faculty of Medical and Health Science, Tel Aviv University, Tel-Aviv, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R\u00e9ba\u00ef","family":"Soret","sequence":"additional","affiliation":[{"name":"ISAE-SUPAERO, Universit\u00e9 de Toulouse, Toulouse, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pom","family":"Charras","sequence":"additional","affiliation":[{"name":"Univ Paul Val\u00e9ry Montpellier 3, Montpellier, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vsevolod","family":"Peysakhovich","sequence":"additional","affiliation":[{"name":"ISAE-SUPAERO, Universit\u00e9 de Toulouse, Toulouse, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anat","family":"Mirelman","sequence":"additional","affiliation":[{"name":"Laboratory for Early Markers of Neurodegeneration (LEMON), Center for the Study of Movement, Cognition, and Mobility (CMCM), Tel Aviv Sourasky Medical Center, Neurological Institute, Tel Aviv, Israel"},{"name":"Faculty of Medical and Health Science, Tel Aviv University, Tel-Aviv, Israel"},{"name":"Sagol School of Neuroscience, Tel Aviv University, Tel Aviv-Yafo, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel A.","family":"Levy","sequence":"additional","affiliation":[{"name":"Baruch Ivcher School of Psychology, Reichman University, Herzliya, Israel"},{"name":"Department of Psychology, Palo Alto University, Palo Alto, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inbal","family":"Maidan","sequence":"additional","affiliation":[{"name":"Laboratory for Early Markers of Neurodegeneration (LEMON), Center for the Study of Movement, Cognition, and Mobility (CMCM), Tel Aviv Sourasky Medical Center, Neurological Institute, Tel Aviv, Israel"},{"name":"Faculty of Medical and Health Science, Tel Aviv University, Tel-Aviv, Israel"},{"name":"Sagol School of Neuroscience, Tel Aviv University, Tel Aviv-Yafo, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,12,23]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/jnp.12028"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-021-00280-3"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1006\/cogp.1999.0734"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1162\/089892902760807159"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.2002.87.5.2577"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-008045046-9.00426-5"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/bs.pbr.2022.01.019"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1080\/23279095.2021.1951268"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.23005"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-6918(99)00047-5"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2005.03.024"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2013.03.008"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.23429"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0707369105"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2012.09.027"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.24.1.167"},{"key":"e_1_3_4_18_2","first-page":"1","article-title":"Attention to action: willed and automatic control of behavior","volume":"4","author":"Norman D","year":"1986","unstructured":"Norman D, Shallice T. Attention to action: willed and automatic control of behavior. Cognit Neurosci: A reader. 1986;4:1-18.","journal-title":"Cognit Neurosci: A reader"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.240460497"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1103-13.2013"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(00)00593-5"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2007.2055"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a009621"},{"key":"e_1_3_4_24_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2915"},{"key":"e_1_3_4_25_2","doi-asserted-by":"publisher","DOI":"10.1177\/1545968311403493"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2015.06.014"},{"key":"e_1_3_4_27_2","doi-asserted-by":"publisher","DOI":"10.1037\/neu0000973"},{"key":"e_1_3_4_28_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26424"},{"key":"e_1_3_4_29_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.17.5.427"},{"key":"e_1_3_4_30_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2005.53221.x"},{"key":"e_1_3_4_31_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198402233100802"},{"key":"e_1_3_4_32_2","doi-asserted-by":"publisher","DOI":"10.1145\/3317959.3321490"},{"key":"e_1_3_4_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0028-3932(00)00112-3"},{"key":"e_1_3_4_34_2","doi-asserted-by":"publisher","DOI":"10.1037\/0096-1523.30.2.319"},{"key":"e_1_3_4_35_2","doi-asserted-by":"publisher","DOI":"10.3758\/BF03205496"},{"key":"e_1_3_4_36_2","doi-asserted-by":"publisher","DOI":"10.1017\/S1355617797003378"},{"key":"e_1_3_4_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/0028-3932(93)90061-4"},{"key":"e_1_3_4_38_2","doi-asserted-by":"publisher","DOI":"10.1111\/bjop.12082"},{"key":"e_1_3_4_39_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0028-3932(01)00045-8"},{"key":"e_1_3_4_40_2","doi-asserted-by":"publisher","DOI":"10.1037\/0894-4105.20.3.370"},{"key":"e_1_3_4_41_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00702-016-1637-z"},{"key":"e_1_3_4_42_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awg210"},{"key":"e_1_3_4_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2018.07.030"},{"key":"e_1_3_4_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2021.02.009"},{"key":"e_1_3_4_45_2","doi-asserted-by":"publisher","DOI":"10.1037\/amp0000263"},{"key":"e_1_3_4_46_2","doi-asserted-by":"publisher","DOI":"10.1037\/a0031542"},{"key":"e_1_3_4_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2009.12.048"},{"key":"e_1_3_4_48_2","doi-asserted-by":"publisher","DOI":"10.1002\/pmrj.12337"},{"key":"e_1_3_4_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2016.08.010"}],"container-title":["Journal of Geriatric Psychiatry and Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/08919887241311170","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/08919887241311170","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/08919887241311170","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:17:00Z","timestamp":1777501020000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/08919887241311170"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,23]]},"references-count":48,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1177\/08919887241311170"],"URL":"https:\/\/doi.org\/10.1177\/08919887241311170","relation":{},"ISSN":["0891-9887","1552-5708"],"issn-type":[{"value":"0891-9887","type":"print"},{"value":"1552-5708","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,23]]}}}