{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T23:32:11Z","timestamp":1777851131385,"version":"3.51.4"},"reference-count":39,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T00:00:00Z","timestamp":1747353600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Peri-operative Cognitive Anesthesia Network","award":["K07AG066813"],"award-info":[{"award-number":["K07AG066813"]}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["P01AG031720"],"award-info":[{"award-number":["P01AG031720"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R01AG044518"],"award-info":[{"award-number":["R01AG044518"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R33AG071744"],"award-info":[{"award-number":["R33AG071744"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Geriatr Psychiatry Neurol"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Delirium is a common yet preventable complication of hospitalization, surgery and illness that is associated with poor outcomes. Older adults with Alzheimer\u2019s Disease and Related Dementias (ADRD) are especially vulnerable to delirium and experience greater delirium severity, yet no existing assessment tool is specifically designed to evaluate this vulnerable population. This study will validate two new delirium severity instruments, the Delirium Severity (DEL-S) rating for all older adults and the Delirium Severity Rating in ADRD (DEL-S-AD) for patients with dementia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design\/Setting and Participants<\/jats:title>\n                    <jats:p>The Better ASsessment of ILlness II (BASIL II) study is an innovative prospective cohort study that measures cognitive function, delirium, delirium severity, demographics, clinical and functional variables and clinical outcomes. Participants include older adults from 3 unique yet complementary clinical sites: medical inpatients, elective surgery inpatients, or skilled nursing facility residents.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Performance of DEL-S and DEL-S-AD items in older adults with cognition ranging from no impairment to moderate impairment will be determined. Analyses will include psychometric characteristics of DEL-S and DEL-S-AD items, harmonization of the two scales and validation against reference standard diagnoses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Implications<\/jats:title>\n                    <jats:p>Results from this study will help accurately measure delirium severity, a critically important, graded outcome. The DEL-S-AD instrument holds broad applications in persons with and without ADRD to monitor delirium severity in clinical settings, and as an outcome measure in future clinical treatment trials and pathophysiologic studies. Ultimately, the DEL-S and DEL-S-AD have the potential to improve health care for the vulnerable, growing population of older adults with cognitive impairment worldwide.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/08919887251343604","type":"journal-article","created":{"date-parts":[[2025,5,17]],"date-time":"2025-05-17T02:13:14Z","timestamp":1747447994000},"page":"79-89","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Better Assessment of Illness Study (BASIL) II for Delirium Severity: Study Design, Variables, and Methods"],"prefix":"10.1177","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8673-6681","authenticated-orcid":false,"given":"Tammy T.","family":"Hshieh","sequence":"first","affiliation":[{"name":"Hinda and Arthur Marcus Institute for Aging Research"},{"name":"Brigham and Women\u2019s Hospital, Division of Aging"},{"name":"Harvard Medical School"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin A.","family":"Chapin","sequence":"additional","affiliation":[{"name":"University of Florida"},{"name":"Geriatric Research Education and Clinical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wingyun","family":"Mak","sequence":"additional","affiliation":[{"name":"The New Jewish Home"},{"name":"Research Institute on Aging"},{"name":"Geriatrics and Palliative Care"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guoquan","family":"Xu","sequence":"additional","affiliation":[{"name":"Hinda and Arthur Marcus Institute for Aging Research"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva M.","family":"Schmitt","sequence":"additional","affiliation":[{"name":"Hinda and Arthur Marcus Institute for Aging Research"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward R.","family":"Marcantonio","sequence":"additional","affiliation":[{"name":"Harvard Medical School"},{"name":"Beth Israel Deaconess Medical Center"},{"name":"Beth Israel Deaconess Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannah","family":"Shanes","sequence":"additional","affiliation":[{"name":"Hinda and Arthur Marcus Institute for Aging Research"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6732-2696","authenticated-orcid":false,"given":"Cole","family":"Heine","sequence":"additional","affiliation":[{"name":"Hinda and Arthur Marcus Institute for Aging Research"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jordan","family":"Helfand","sequence":"additional","affiliation":[{"name":"Brown University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Price","sequence":"additional","affiliation":[{"name":"University of Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth S.","family":"Boockvar","sequence":"additional","affiliation":[{"name":"The New Jewish Home"},{"name":"Research Institute on Aging"},{"name":"University of Alabama"},{"name":"Birmingham VA Health Care System"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eran D.","family":"Metzger","sequence":"additional","affiliation":[{"name":"Hinda and Arthur Marcus Institute for Aging Research"},{"name":"Harvard Medical School"},{"name":"Beth Israel Deaconess Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamara G.","family":"Fong","sequence":"additional","affiliation":[{"name":"Hinda and Arthur Marcus Institute for Aging Research"},{"name":"Harvard Medical School"},{"name":"Beth Israel Deaconess Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard N.","family":"Jones","sequence":"additional","affiliation":[{"name":"Warren Alpert Medical School"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharon K.","family":"Inouye","sequence":"additional","affiliation":[{"name":"Hinda and Arthur Marcus Institute for Aging Research"},{"name":"Harvard Medical School"},{"name":"Beth Israel Deaconess Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"for the BASIL II Study Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,5,16]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.12067"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2007.4"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(13)60688-1"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181a4129a"},{"key":"e_1_3_6_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2012.3203"},{"key":"e_1_3_6_7_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-156-12-201206190-00005"},{"key":"e_1_3_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(15)00101-5"},{"key":"e_1_3_6_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2018.6975"},{"key":"e_1_3_6_10_2","doi-asserted-by":"publisher","DOI":"10.7326\/M13-1927"},{"key":"e_1_3_6_11_2","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_3_6_12_2","doi-asserted-by":"publisher","DOI":"10.7326\/M14-0865"},{"key":"e_1_3_6_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2018.6975"},{"key":"e_1_3_6_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.17624"},{"key":"e_1_3_6_15_2","doi-asserted-by":"publisher","DOI":"10.3928\/00989134-20240809-06"},{"key":"e_1_3_6_16_2","doi-asserted-by":"publisher","DOI":"10.3928\/00989134-20240809-06"},{"key":"e_1_3_6_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.13793"},{"key":"e_1_3_6_18_2","volume-title":"Protocols for Physician Notification: Assessing and Collecting Data on Nursing Facility Patients: A Guide for Nurses on Effective Communication with Physicians","author":"Levensen S","year":"2004","unstructured":"Levensen S, Vance J. Protocols for Physician Notification: Assessing and Collecting Data on Nursing Facility Patients: A Guide for Nurses on Effective Communication with Physicians. Chicago: American Medical Director\u2019s Association; 2004."},{"key":"e_1_3_6_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.16695"},{"key":"e_1_3_6_20_2","doi-asserted-by":"publisher","DOI":"10.1159\/000506700"},{"key":"e_1_3_6_21_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2022.6129"},{"key":"e_1_3_6_22_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-019-02201-0"},{"key":"e_1_3_6_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.17624"},{"key":"e_1_3_6_24_2","article-title":"The family confusion assessment method (FAM-CAM): instrument and training manual","author":"Inouye SKPM","unstructured":"Inouye SKPM, Saczynski JS, Steis MR. The family confusion assessment method (FAM-CAM): instrument and training manual. Hospital Elder Life Program. https:\/\/www.hospitalelderlifeprogram.org\/","journal-title":"Hospital Elder Life Program"},{"key":"e_1_3_6_25_2","doi-asserted-by":"publisher","DOI":"10.1017\/s1041610298005493"},{"key":"e_1_3_6_26_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-113-12-941"},{"key":"e_1_3_6_27_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-019-1129-8"},{"key":"e_1_3_6_28_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2005.53221.x"},{"key":"e_1_3_6_29_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000172958.95282.2a"},{"issue":"1","key":"e_1_3_6_30_2","first-page":"31","article-title":"Performance of the dementia severity rating scale: a caregiver Questionnaire for rating severity in alzheimer disease","volume":"10","author":"Clark CM","year":"1996","unstructured":"Clark CM, Ewbank DC. Performance of the dementia severity rating scale: a caregiver Questionnaire for rating severity in alzheimer disease. Alzheimer Dis Assoc Disord. 1996;10(1):31-39.","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"e_1_3_6_31_2","doi-asserted-by":"publisher","DOI":"10.1111\/ijcp.12188"},{"key":"e_1_3_6_32_2","doi-asserted-by":"publisher","DOI":"10.1111\/ijcp.12188"},{"key":"e_1_3_6_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90171-8"},{"key":"e_1_3_6_34_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-198510000-00009"},{"key":"e_1_3_6_35_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1497.2001.016009606.x"},{"key":"e_1_3_6_36_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199603000-00003"},{"key":"e_1_3_6_37_2","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.111.095273"},{"key":"e_1_3_6_38_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2022.6129"},{"key":"e_1_3_6_39_2","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.18631"},{"key":"e_1_3_6_40_2","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9780511996214"}],"container-title":["Journal of Geriatric Psychiatry and Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/08919887251343604","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/08919887251343604","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/08919887251343604","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:17:07Z","timestamp":1777501027000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/08919887251343604"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,16]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1177\/08919887251343604"],"URL":"https:\/\/doi.org\/10.1177\/08919887251343604","relation":{},"ISSN":["0891-9887","1552-5708"],"issn-type":[{"value":"0891-9887","type":"print"},{"value":"1552-5708","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,16]]}}}