{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T10:50:25Z","timestamp":1782211825204,"version":"3.54.5"},"reference-count":17,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T00:00:00Z","timestamp":1759190400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Endourology"],"published-print":{"date-parts":[[2025,11,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Patients with exstrophy\u2013epispadias complex (EEC) often present with attenuated fascia. Currently, there is no direct comparison of outcomes between percutaneous cystolitholapaxy and open cystolithotomy in this specific patient population. Thus, we sought to evaluate the therapeutic efficacy and associated morbidity of both surgical approaches in patients with EEC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Patients who underwent either their first percutaneous cystolitholapaxy or open cystolithotomy between 2003 and 2023 were identified using an IRB-approved institutional database of 1512 patients with EEC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Among 66 patients, 8 (12.12%) underwent percutaneous cystolitholapaxy without augmentation, 31 (46.97%) underwent percutaneous cystolitholapaxy with augmentation, 11 (16.67%) underwent open cystolithotomy without augmentation, and 16 (24.24%) underwent open cystolithotomy with augmentation. Compared with the open approach, the percutaneous approach resulted in shorter operative times: 123 (interquartile ranges [IQR]: 81\u2013151)\n                      <jats:italic toggle=\"yes\">vs<\/jats:italic>\n                      218 minutes (IQR: 142\u2013281) for patients with augmentation, and 131 (IQR: 115.5\u2013141)\n                      <jats:italic toggle=\"yes\">vs<\/jats:italic>\n                      196 minutes (IQR: 176.5\u2013287.3) for those without augmentation (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.0002). Hospital stays were shorter with the percutaneous approach: 1 (IQR: 1\u20131)\n                      <jats:italic toggle=\"yes\">vs<\/jats:italic>\n                      3 days (IQR: 1\u20134) with augmentation, and 1.5 (IQR: 1\u20132)\n                      <jats:italic toggle=\"yes\">vs<\/jats:italic>\n                      3 days (IQR: 1\u20134) without augmentation (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.0044). Notably, the percutaneous group had smaller stone volumes (7.15 cm\n                      <jats:sup>3<\/jats:sup>\n                      , IQR: 2.73\u201324.31\n                      <jats:italic toggle=\"yes\">vs<\/jats:italic>\n                      31.04 cm\n                      <jats:sup>3<\/jats:sup>\n                      , IQR: 10.77\u2013107.40,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.0011). Both techniques achieved a 100% stone-free rate (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &gt; 0.99). There were no differences in recurrence (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.20) and cumulative incidence (HR 0.76, 95% confidence interval: 0.39\u20131.48,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.38) between groups. Postoperative complications revealed that vesicocutaneous fistulas were most common in open surgery without augmentation (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 5, 45.45%), followed by open with augmentation (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 1, 6.25%), and none in the percutaneous groups (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.0002).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Percutaneous cystolitholapaxy provided significant advantages for patients with EEC, including shorter operative times and reduced hospital stays, with equivalent stone clearance. Moreover, open cystolithotomy carried a higher risk of vesicocutaneous fistula formation. These findings suggest percutaneous approaches may offer a safer and more efficient alternative for managing bladder stones in patients with EEC.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/08927790251384294","type":"journal-article","created":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T16:04:42Z","timestamp":1759248282000},"page":"1172-1180","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Percutaneous Cystolitholapaxy and Open Cystolithotomy in Exstrophy\u2013Epispadias Complex: A Comparative Approach to Bladder Stone Management"],"prefix":"10.1177","volume":"39","author":[{"given":"Jason","family":"Yang","sequence":"first","affiliation":[{"name":"Robert D. Jeffs Division of Pediatric Urology, James Buchanan Brady Urological Institutions, Johns Hopkins Hospital, Johns Hopkins Medical Institutions, Charlotte Bloomberg Children\u2019s Hospital, Baltimore, Maryland, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Heap","sequence":"additional","affiliation":[{"name":"Robert D. Jeffs Division of Pediatric Urology, James Buchanan Brady Urological Institutions, Johns Hopkins Hospital, Johns Hopkins Medical Institutions, Charlotte Bloomberg Children\u2019s Hospital, Baltimore, Maryland, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Maxon","sequence":"additional","affiliation":[{"name":"Robert D. Jeffs Division of Pediatric Urology, James Buchanan Brady Urological Institutions, Johns Hopkins Hospital, Johns Hopkins Medical Institutions, Charlotte Bloomberg Children\u2019s Hospital, Baltimore, Maryland, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Robey","sequence":"additional","affiliation":[{"name":"Robert D. Jeffs Division of Pediatric Urology, James Buchanan Brady Urological Institutions, Johns Hopkins Hospital, Johns Hopkins Medical Institutions, Charlotte Bloomberg Children\u2019s Hospital, Baltimore, Maryland, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahir","family":"Maruf","sequence":"additional","affiliation":[{"name":"Division of Endourology, James Buchanan Brady Urological Institutions, Johns Hopkins Hospital, Baltimore, Maryland, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chloe","family":"Michel","sequence":"additional","affiliation":[{"name":"Division of Endourology, James Buchanan Brady Urological Institutions, Johns Hopkins Hospital, Baltimore, Maryland, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather N.","family":"Di Carlo","sequence":"additional","affiliation":[{"name":"Robert D. Jeffs Division of Pediatric Urology, James Buchanan Brady Urological Institutions, Johns Hopkins Hospital, Johns Hopkins Medical Institutions, Charlotte Bloomberg Children\u2019s Hospital, Baltimore, Maryland, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John P.","family":"Gearhart","sequence":"additional","affiliation":[{"name":"Robert D. Jeffs Division of Pediatric Urology, James Buchanan Brady Urological Institutions, Johns Hopkins Hospital, Johns Hopkins Medical Institutions, Charlotte Bloomberg Children\u2019s Hospital, Baltimore, Maryland, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7127-4322","authenticated-orcid":false,"given":"Chad B.","family":"Crigger","sequence":"additional","affiliation":[{"name":"Robert D. Jeffs Division of Pediatric Urology, James Buchanan Brady Urological Institutions, Johns Hopkins Hospital, Johns Hopkins Medical Institutions, Charlotte Bloomberg Children\u2019s Hospital, Baltimore, Maryland, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,9,30]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005392-199709000-00175"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2024.07.001"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10029-015-1414-1"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/JU.0000000000001510"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2023.05.009"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1089\/end.2013.0127"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-025-05464-0"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.02.040"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000023529.61701.ce"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2010.01.033"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2023.04.024"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2013.11.057"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1089\/end.1999.13.739"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2014.02.012"},{"key":"e_1_3_2_16_2","first-page":"19907","article-title":"Minimally invasive percutaneous suprapubic cystolithotripsy: An effective treatment for bladder stones with urethral strictures","volume":"9","author":"Liu G","year":"2016","unstructured":"Liu G, , Deng Y, , Zhang S, et al. Minimally invasive percutaneous suprapubic cystolithotripsy: An effective treatment for bladder stones with urethral strictures. Int J Clin Exp Med, 2016; 9:19907\u201319912.","journal-title":"Int J Clin Exp Med"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1089\/end.1999.13.173"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2023.04.022"}],"container-title":["Journal of Endourology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/08927790251384294","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/08927790251384294","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/08927790251384294","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T10:33:49Z","timestamp":1782210829000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/08927790251384294"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,30]]},"references-count":17,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11,1]]}},"alternative-id":["10.1177\/08927790251384294"],"URL":"https:\/\/doi.org\/10.1177\/08927790251384294","relation":{},"ISSN":["0892-7790","1557-900X"],"issn-type":[{"value":"0892-7790","type":"print"},{"value":"1557-900X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,30]]}}}