{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T01:56:26Z","timestamp":1787622986589,"version":"build-2736575974"},"reference-count":17,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T00:00:00Z","timestamp":1768953600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Endourology"],"published-print":{"date-parts":[[2026,2,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To evaluate outcomes after water vapor thermal therapy (WVTT) for benign prostatic hyperplasia (BPH), stratified by varying degrees of median lobe (ML) protrusion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods:<\/jats:title>\n                    <jats:p>We enrolled men aged \u226545 years with BPH who underwent WVTT from July 2020 to September 2023. Inclusion criteria were an estimated prostate volume of 30\u201380 cc, International Prostate Symptom Score (IPSS) \u226512, and maximum urinary flow rate &lt;16 mL\/sec. ML protrusion was assessed using ultrasound (with bladder volume \u2265250 cc) and flexible cystoscopy; the average of both measurements was used to classify ML protrusion into &lt;5 mm, 5\u201310 mm, and &gt;10 mm. Primary outcomes included postoperative complications such as surgical retreatment, acute urinary retention (AUR), and urinary tract infections (UTIs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      With a median follow-up of 29.1 months (range: 24\u201336), improvements in lower urinary tract symptoms (LUTS) were similar across all groups, with consistent symptom reduction (\u0394 = \u221213) in both obstructive and irritative IPSS components. Rates of AUR and UTIs showed no significant variation across groups: AUR (no ML 9.5%; &lt;5 mm 8.7%; 5\u201310 mm 12%; &gt;10 mm 17%;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.7) and UTI (no ML 8.4%; &lt;5 mm 4.3%; 5\u201310 mm 9.3%; &gt;10 mm 8.3%;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.8). Despite comparable preoperative characteristics, surgical retreatment rates varied significantly with ML protrusion: no ML (3.2%), &lt;5 mm (4.3%), 5\u201310 mm (14%), and &gt;10 mm (21%) (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.007), highlighting increased retreatment risk associated with greater ML protrusion.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>WVTT effectively relieves LUTS across all ML configurations. However, patients with greater ML protrusion may face a higher risk of retreatment, likely because of increased bladder neck and urethral involvement. These findings suggest that detailed ML assessment can aid in patient counseling and stratification.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/08927790251412401","type":"journal-article","created":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T06:01:15Z","timestamp":1769061675000},"page":"205-211","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of Median Lobe Protrusion on Outcomes of Water Vapor Thermal Therapy for Benign Prostatic Hyperplasia: A Prospective Analysis"],"prefix":"10.1177","volume":"40","author":[{"given":"Juan","family":"Fulla","sequence":"first","affiliation":[{"name":"Department of Urology, Hospital Cl\u00ednico San Borja Arriar\u00e1n, Santiago, Chile."},{"name":"Department of Urology, University of Chile, Santiago, Chile."},{"name":"Cl\u00ednica MEDS, Santiago, Chile."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Sebastian","family":"Arroyave","sequence":"additional","affiliation":[{"name":"Department of Urology, Icahn School of Medicine at Mount Sinai, New York, New York, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisca","family":"Larenas","sequence":"additional","affiliation":[{"name":"Department of Urology, Hospital Cl\u00ednico San Borja Arriar\u00e1n, Santiago, Chile."},{"name":"Department of Urology, University of Chile, Santiago, Chile."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven A.","family":"Kaplan","sequence":"additional","affiliation":[{"name":"Department of Urology, Icahn School of Medicine at Mount Sinai, New York, New York, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Palese","sequence":"additional","affiliation":[{"name":"Department of Urology, Icahn School of Medicine at Mount Sinai, New York, New York, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Sanchez","sequence":"additional","affiliation":[{"name":"Cl\u00ednica MEDS, Santiago, Chile."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,1,21]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-020-03457-9"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2016.31"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-06628-8"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2014.12.038"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-024-05017-x"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2005.12.042"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.euros.2022.03.006"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/JU.0000000000001778"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.5173\/ceju.2011.02.art5"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1159\/000049784"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.2147\/RRU.S143679"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.2147\/RRU.S119596"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41391-017-0022-9"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.purol.2020.05.004"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/pros.24201"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2022.02.001"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2017.10.023"}],"container-title":["Journal of Endourology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/08927790251412401","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/08927790251412401","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/08927790251412401","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T20:17:48Z","timestamp":1777407468000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/08927790251412401"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,21]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2,1]]}},"alternative-id":["10.1177\/08927790251412401"],"URL":"https:\/\/doi.org\/10.1177\/08927790251412401","relation":{},"ISSN":["0892-7790","1557-900X"],"issn-type":[{"value":"0892-7790","type":"print"},{"value":"1557-900X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,21]]}}}