{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T22:53:34Z","timestamp":1777589614786,"version":"3.51.4"},"reference-count":28,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:00:00Z","timestamp":1768435200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Endourology"],"published-print":{"date-parts":[[2026,2,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>This study aimed to evaluate the feasibility and safety of patients undergoing holmium laser enucleation of prostate (HoLEP), under transurethral intraprostatic anesthesia (TUIA) using Schelin Catheter (SC) and sedoanalgesia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>We retrospectively analyzed data of patients affected by benign prostatic obstruction candidate to HoLEP under TUIA using SC, from November 2023 to May 2024.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 50 patients were enrolled, median age 67 years; 14% were ASA \u2265 3, 2% and 22% had anticoagulation and antiplatelet drug therapy; 60% received alpha blockers, and 22% had both alpha blockers and 5\u03b1-reductase inhibitors; and 18% with an indwelling catheter. Preoperative median International Prostate Symptom Score (IPSS) and IPSS-quality of life (IPSS-QoL) were 16 (IQR: 11\u201321) and 4 (IQR: 4\u20136), median Qmax 10 mL\/sec (IQR 3\u201319), median postvoid residual (PVR) 79 mL (IQR: 0\u2013500). The median prostate volume was 50 mL (IQR 41\u201370 cc). Median preoperative Prostate Specific Antigen (PSA) was 1,70 (IQR 1,1\u20132,95). A prostate volume \u2265 80 mL was present in 10% of patients. The median enucleation time was 13,6 minutes (IQR 11,15\u201321,45) and the median morcellation time was 8,3 minutes (IQR 4,2\u201310,8). The median enucleated weight was 33 g (IQR 19,50\u201350). Median pain numeric rating scale before surgical procedure, at SC insertion, during enucleation, during morcellation, 2-hours postoperatively, on day 1 and 2 were 1 (0\u20133), 5 (2\u20136), 5 (3\u20137), 7 (5\u201310), 2 (1\u20134), 2 (1\u20134), and 3 (2\u20136). During enucleation, 10% required to start the target-controlled infusion with propofol. During morcellation, a half needs to get started propofol administration. The catheter was removed within 2 days in 100% of patients, and all were discharged within 48 hours. IPSS, IPSS-QoL, Qmax, and PVR showed significant improvement at 3 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>TUIA with sedoanalgesia in HoLEP of small\/medium prostate volume offers good pain control, preserving the significant improvement of postoperative outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/08927790251414138","type":"journal-article","created":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T11:12:04Z","timestamp":1768475524000},"page":"212-218","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Feasibility and Safety of Holmium Laser Enucleation of the Prostate for Small to Medium Volumes Under Local Anesthesia with the Schelin Catheter and Sedoanalgesia: Results from a Single-Center Pilot Study"],"prefix":"10.1177","volume":"40","author":[{"given":"Gianna","family":"Pace","sequence":"first","affiliation":[{"name":"Department of Urology, Policlinico Abano Terme, Padua, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele","family":"Romagnoli","sequence":"additional","affiliation":[{"name":"Department of Urology, Policlinico Abano Terme, Padua, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"del Rosso","sequence":"additional","affiliation":[{"name":"Department of Urology, Policlinico Abano Terme, Padua, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Vidiri","sequence":"additional","affiliation":[{"name":"Department of Urology, Policlinico Abano Terme, Padua, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Orest","family":"Xhafka","sequence":"additional","affiliation":[{"name":"Department of Urology, Policlinico Abano Terme, Padua, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianluca","family":"Brunetti","sequence":"additional","affiliation":[{"name":"Department of Urology, Policlinico Abano Terme, Padua, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,1,15]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2009.08371.x"},{"issue":"1","key":"e_1_3_2_3_2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/RGTW5711","article-title":"Development of a clinical decision support tool for primary care management of lower urinary tract symptoms in men: The PriMUS study","volume":"29","author":"Edwards A","year":"2025","unstructured":"Edwards A, , Agarwal R, , Bates J, et al. Development of a clinical decision support tool for primary care management of lower urinary tract symptoms in men: The PriMUS study. Health Technol Assess, 2025; 29(1):1\u2013140.","journal-title":"Health Technol Assess"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2009.06.037"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/bju.12281"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2004.03.033"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2006.11.062"},{"issue":"2","key":"e_1_3_2_8_2","first-page":"6","article-title":"HoLEP: The new gold standard for surgical treatment of benign prostatic hyperplasia","volume":"28","author":"Shvero A","year":"2021","unstructured":"Shvero A, , Calio B, , Humphreys MR, et al. HoLEP: The new gold standard for surgical treatment of benign prostatic hyperplasia. Can J Urol, 2021; 28(S2):6\u201310.","journal-title":"Can J Urol"},{"issue":"4","key":"e_1_3_2_9_2","first-page":"408","article-title":"Comparison of 3 different enucleation techniques of HoLEP","volume":"17","author":"Tokatli Z","year":"2020","unstructured":"Tokatli Z, , Esen B, , Yaman \u00d6, et al. Comparison of 3 different enucleation techniques of HoLEP. Urol J, 2020; 17(4):408\u2013412.","journal-title":"Urol J"},{"issue":"3","key":"e_1_3_2_10_2","first-page":"366","article-title":"T-L technique for HoLEP: Perioperative outcomes of a large single-centre series","volume":"74","author":"Porreca A","year":"2021","unstructured":"Porreca A, , Schiavina R, , Romagnoli D, et al. T-L technique for HoLEP: Perioperative outcomes of a large single-centre series. Cent European J Urol, 2021; 74(3):366\u2013371.","journal-title":"Cent European J Urol"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2021.04.078"},{"issue":"2","key":"e_1_3_2_12_2","first-page":"273","article-title":"Holmium laser enucleation of the prostate with transurethral intraprostatic anesthesia using Schelin catheter: A preliminary communication","volume":"77","author":"Romagnoli D","year":"2024","unstructured":"Romagnoli D, , Bianchi A, , Oddi A, et al. Holmium laser enucleation of the prostate with transurethral intraprostatic anesthesia using Schelin catheter: A preliminary communication. Cent European J Urol, 2024; 77(2):273\u2013277.","journal-title":"Cent European J Urol"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1080\/00365590802465061"},{"issue":"1","key":"e_1_3_2_14_2","first-page":"11802","article-title":"Use of the Schelin Catheter for transurethral intraprostatic anesthesia prior to Rez\u016bm treatment","volume":"31","author":"Hamouda A","year":"2024","unstructured":"Hamouda A, , Ibrahim A, , Corsi N, et al. Use of the Schelin Catheter for transurethral intraprostatic anesthesia prior to Rez\u016bm treatment. Can J Urol, 2024; 31(1):11802\u201311808.","journal-title":"Can J Urol"},{"issue":"12","key":"e_1_3_2_15_2","first-page":"e75579","article-title":"Short- and medium-term outcomes assessment of urethral prostatic lift (UroLift) as a minimally invasive treatment for benign prostatic hyperplasia in a Tertiary Care Centre","volume":"16","author":"Akpala A","year":"2024","unstructured":"Akpala A, , Lezama T, , Hussain M, et al. 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