{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T03:35:07Z","timestamp":1791689707497,"version":"4.3.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Endourology"],"published-print":{"date-parts":[[2026,4,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Sarcopenia, the generalized loss of muscle mass, has been linked to outcomes across various medical specialties, but remains understudied in Endourology. This study aimed to evaluate whether sarcopenia serves as a prognostic indicator in elderly patients undergoing percutaneous nephrolithotomy (PCNL).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods:<\/jats:title>\n                    <jats:p>Patients \u226570 years who underwent PCNL between January 2021 and December 2022 were identified retrospectively. Sarcopenia was determined using preoperative CT. Postoperative outcomes were compared between sarcopenic patients and non-sarcopenic controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 234 patients were included, with 148 (63%) meeting criterion for sarcopenia. There was no difference in mean age, co-morbidities, or cumulative linear stone burden (18.8 mm vs. 20.5 mm,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.21) between the groups; however, sarcopenia was significantly more prevalent among men compared to women (77%\n                      <jats:italic toggle=\"yes\">vs<\/jats:italic>\n                      47.2%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; .001). Patients with sarcopenia experienced higher rates of Clavien\u2013Dindo grade \u22652 complications (20%\n                      <jats:italic toggle=\"yes\">vs<\/jats:italic>\n                      8%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.02) compared to controls and trended toward higher rates of perioperative transfusions (7%\n                      <jats:italic toggle=\"yes\">vs<\/jats:italic>\n                      1%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.06). Unanticipated ED visits were higher among patients with sarcopenia (24%\n                      <jats:italic toggle=\"yes\">vs<\/jats:italic>\n                      9%;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.01). On multivariate analysis, patients with sarcopenia were 2.8 times more likely to experience complications (odds ratio = 2.78,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.024) and had a 43% longer hospital stay (time ratio = 1.43,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Sarcopenia is associated with less favorable perioperative outcomes in elderly patients undergoing PCNL, with higher complication rates, increased emergency room\u00a0visits, and prolonged hospital stays. We present a novel risk-stratification tool to help identify patients at increased risk of adverse events after PCNL, which may serve as a valuable adjunct in perioperative risk estimation and preoperative counseling in this high-risk population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/08927790261427824","type":"journal-article","created":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T05:00:58Z","timestamp":1772427658000},"page":"462-467","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Sarcopenia Is Associated with Worse Perioperative Outcomes in Elderly Patients after Percutaneous Nephrolithotomy"],"prefix":"10.1177","volume":"40","author":[{"given":"Cyrus","family":"Chehroudi","sequence":"first","affiliation":[{"name":"Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haitong","family":"Yu","sequence":"additional","affiliation":[{"name":"School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishu","family":"Chandrasekhar","sequence":"additional","affiliation":[{"name":"School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Austin","family":"Thompson","sequence":"additional","affiliation":[{"name":"School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louisa","family":"Ho","sequence":"additional","affiliation":[{"name":"Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianbo","family":"Li","sequence":"additional","affiliation":[{"name":"Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Gutierrez-Aceves","sequence":"additional","affiliation":[{"name":"Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Zampini","sequence":"additional","affiliation":[{"name":"Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smita","family":"De","sequence":"additional","affiliation":[{"name":"Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sri","family":"Sivalingam","sequence":"additional","affiliation":[{"name":"Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,3,1]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare11030424"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2012.09.023"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2016.05.090"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/JU.0000000000003397"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.56787"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2012.12.010"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2019.08.044"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1089\/end.2012.0046"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afr182"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)31138-9"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/bju.16434"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/MOU.0000000000000885"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11701-024-02133-z"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/JS9.0000000000000688"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/bju.16606"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(08)70153-0"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1177\/000313480306901109"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajur.2015.08.005"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-021-03681-x"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glv129"},{"issue":"10","key":"e_1_3_2_22_2","first-page":"180","article-title":"Quantifying 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Quantifying sarcopenia reference values using lumbar and thoracic muscle areas in a healthy population. 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