{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:38:17Z","timestamp":1777927097368,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2022,1,12]],"date-time":"2022-01-12T00:00:00Z","timestamp":1641945600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perit Dial Int"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:p>In the absence of guidelines on the management of peritoneal dialysis (PD)-associated peritonitis in patients on automated peritoneal dialysis (APD), variations in clinical practice potentially exist between PD units that could affect clinical outcomes. This study aimed to document the current practices of treating PD-associated peritonitis in patients on APD across Australia and New Zealand and the reasons for practice variations using a cross-sectional online survey. Of the 62 PD units, 34 medical leads (55%) responded to the survey. When treating APD-associated peritonitis, 21 units (62%) continued patients on APD and administered intraperitoneal (IP) antibiotics in manual daytime exchanges; of these, 17 (81%) considered allowing at least 6 h dwell time for adequate absorption of the IP antibiotics as an important reason for adding manual daytime exchange. Nine units (26%) temporarily switched patients from APD to continuous ambulatory peritoneal dialysis (CAPD); of these, five (55%) reported a lack of pharmacokinetic (PK) data for IP antibiotics in APD, four (44%) reported a shortage of APD-trained nursing staff to perform APD exchanges during hospitalisation and three (33%) reported inadequate time for absorption of IP antibiotics on APD as important reasons for their practice. Four units (12%) continued patients on APD and administered IP antibiotics during APD exchanges; of these, three (75%) believed that PK data available in CAPD could be extrapolated to APD. This study demonstrates wide variations in the management of APD-associated peritonitis in Australia and New Zealand; it points towards the lack of PK on antibiotics used to treat peritonitis as an important reason underpinning practice variations.<\/jats:p>","DOI":"10.1177\/08968608211069231","type":"journal-article","created":{"date-parts":[[2022,1,12]],"date-time":"2022-01-12T03:20:50Z","timestamp":1641957650000},"page":"647-651","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Practice variations in antibiotic administration for the management of peritonitis in patients on automated peritoneal dialysis in Australia and New Zealand"],"prefix":"10.1177","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6445-4314","authenticated-orcid":false,"given":"Chau Wei","family":"Ling","sequence":"first","affiliation":[{"name":"School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, New South Wales, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kamal","family":"Sud","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine, Nepean, Blacktown and Westmead Hospital, Sydney, New South Wales, Australia"},{"name":"Faculty of Medicine and Health, Nepean Clinical School, Sydney, New South Wales, Australia"},{"name":"Peritoneal Dialysis Unit, Regional Dialysis Centre, Blacktown Hospital, New South Wales, Australia"},{"name":"Australia and New Zealand Dialysis and Transplant Registry (ANZDATA) Peritoneal Dialysis Working Group, Adelaide, South Australia, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Connie","family":"Van","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, New South Wales, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory M","family":"Peterson","sequence":"additional","affiliation":[{"name":"School of Pharmacy and Pharmacology, University of Tasmania, Hobart, Tasmania, Australia"},{"name":"Faculty of Health, University of Canberra, Bruce, Australian Capital Territory, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9344-1013","authenticated-orcid":false,"given":"Rahul P","family":"Patel","sequence":"additional","affiliation":[{"name":"School of Pharmacy and Pharmacology, University of Tasmania, Hobart, Tasmania, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Syed Tabish Razi","family":"Zaidi","sequence":"additional","affiliation":[{"name":"School of Pharmacy and Pharmacology, University of Tasmania, Hobart, Tasmania, Australia"},{"name":"Professional Services Unit, HPS Pharmacies, EBOS Group, Docklands, Victoria, Australia"},{"name":"School of Healthcare, University of Leeds, West Yorkshire, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald L","family":"Castelino","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, New South Wales, Australia"},{"name":"Department of Pharmacy, Blacktown Hospital, New South Wales, 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