{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T05:02:42Z","timestamp":1781326962161,"version":"3.54.1"},"reference-count":14,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T00:00:00Z","timestamp":1760659200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100004702","name":"Baxter International","doi-asserted-by":"publisher","award":["17CECPDAP1008"],"award-info":[{"award-number":["17CECPDAP1008"]}],"id":[{"id":"10.13039\/100004702","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perit Dial Int"],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Therapy alerts during automated peritoneal dialysis (APD) can cause significant disruptions to patients\u2019 sleep and quality of life and may portend poorer outcomes. Understanding the relationship between alert frequency during this early period and longer-term PD outcomes is important.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Following the probabilistic linkage of Vantive's Sharesource database to the Australian and New Zealand Dialysis and Transplant (ANZDATA) Registry, we examined the relationship between alert frequency in the first 30 days of APD and PD discontinuation. We included adult patients in Australia and New Zealand who commenced APD with the Vantive Homechoice Claria cycler over 2019\u20132023 and continued for at least 30 days. The average alerts per treatment in the first 30 days were divided into quartiles and time to PD discontinuation (inclusive of HD transfer and death), HD transfer only, and infective and non-infective HD transfer were modelled as outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The cohort was 1880 patients, 65% male, and median age at PD commencement of 58 years. Overall PD continuation at 1,2, and 3 years was 78%, 56% and 41%, with HD transfer rates at 14%, 23% and 27%. Higher rates of HD transfer in the first 12 months were seen in the groups with a higher average alert number. Within 12 months, there was a progressive risk of non-infective HD transfer with increasing 30-day alert quartile.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Alert burden in the first 30 days is a risk factor for HD transfer in the first 12 months, and resolving underlying issues early may help to improve PD continuation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/08968608251386224","type":"journal-article","created":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T14:30:21Z","timestamp":1760711421000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Frequency of therapy alerts during the first 30 days of automated peritoneal dialysis and its relationship to time on treatment"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-8385-7615","authenticated-orcid":false,"given":"Annie","family":"Conway","sequence":"first","affiliation":[{"name":"ANZDATA Registry, SAHMRI"},{"name":"The University of Adelaide"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2913-3312","authenticated-orcid":false,"given":"Jarrad","family":"Hopkins","sequence":"additional","affiliation":[{"name":"The University of Adelaide"},{"name":"Central and Northern Adelaide Renal and Transplantation Services (CNARTS), Royal Adelaide Hospital, Adelaide, South Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-5767-8444","authenticated-orcid":false,"given":"Michelle","family":"Ovenden","sequence":"additional","affiliation":[{"name":"Central and Northern Adelaide Renal and Transplantation Services (CNARTS), Royal Adelaide Hospital, Adelaide, South Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monique","family":"Borlace","sequence":"additional","affiliation":[{"name":"Central and Northern Adelaide Renal and Transplantation Services (CNARTS), Royal Adelaide Hospital, Adelaide, South Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5491-3460","authenticated-orcid":false,"given":"David W","family":"Johnson","sequence":"additional","affiliation":[{"name":"Princess Alexandra Hospital"},{"name":"The University of Queensland"},{"name":"Translational Research Institute, Translational Research Institute Australia, Woolloongabba, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8900-2819","authenticated-orcid":false,"given":"Jenny HC","family":"Chen","sequence":"additional","affiliation":[{"name":"Renal Service, Wollongong Hospital"},{"name":"University of Wollongong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7648-007X","authenticated-orcid":false,"given":"Kamal","family":"Sud","sequence":"additional","affiliation":[{"name":"Nepean Kidney Research Centre, Nepean Hospital"},{"name":"The University of Sydney"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5884-640X","authenticated-orcid":false,"given":"Neil","family":"Boudville","sequence":"additional","affiliation":[{"name":"School of Medicine and Pharmacology, The University of Western Australia"},{"name":"Sir Charles Gairdner Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6103-1386","authenticated-orcid":false,"given":"Stephen","family":"McDonald","sequence":"additional","affiliation":[{"name":"ANZDATA Registry, SAHMRI"},{"name":"Central and Northern Adelaide Renal and Transplantation Services (CNARTS), Royal Adelaide Hospital, Adelaide, South Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,10,17]]},"reference":[{"key":"e_1_3_3_2_2","volume-title":"Chapter 5: peritoneal dialysis","author":"Chen J","year":"2023","unstructured":"Chen J, Davies C, Au E, et al. Chapter 5: peritoneal dialysis. Annual {Report} 46, Australia: New Zealand Dialysis; Transplant Registry, 2023."},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.34067\/KID.0000000000000377"},{"key":"e_1_3_3_4_2","first-page":"95","article-title":"Automated cyclers used in peritoneal dialysis: technical aspects for the clinician","volume":"8","author":"Chaudhry RI","year":"2015","unstructured":"Chaudhry RI, Golper TA. Automated cyclers used in peritoneal dialysis: technical aspects for the clinician. Med Dev (Auckland, NZ) 2015; 8: 95\u2013102.","journal-title":"Med Dev (Auckland, NZ)"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2022-061772"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.3390\/jpm14080807"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/0896860820927528"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.34067\/KID.0000302019"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40620-020-00812-2"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1159\/000496318"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1159\/000496997"},{"key":"e_1_3_3_12_2","unstructured":"Baxter Healthcare Corporation. Homechoice Claria APD System Patient At-Home Guide. 2015."},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.32614\/RJ-2021-053"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-09462-9"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0b013e3181c1ea43"}],"container-title":["Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/08968608251386224","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/08968608251386224","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/08968608251386224","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:38:50Z","timestamp":1777675130000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/08968608251386224"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,17]]},"references-count":14,"alternative-id":["10.1177\/08968608251386224"],"URL":"https:\/\/doi.org\/10.1177\/08968608251386224","relation":{},"ISSN":["0896-8608","1718-4304"],"issn-type":[{"value":"0896-8608","type":"print"},{"value":"1718-4304","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,17]]},"article-number":"08968608251386224"}}