{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T19:06:10Z","timestamp":1779044770444,"version":"3.51.4"},"reference-count":57,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T00:00:00Z","timestamp":1761609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["1K23HL151816-01A1"],"award-info":[{"award-number":["1K23HL151816-01A1"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perit Dial Int"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:p>Women with kidney failure have impaired fertility challenges due to disruption of the hypothalamic gonadal axis and hormonal dysregulation, with pregnancy rates on home dialysis being much lower than those with normal kidney function. Pregnant women on dialysis are at high risk of hypertensive disorders, preterm birth, and fetal growth restriction, but intensified dialysis can mitigate these risks. Home dialysis offers advantages like flexibility, better hemodynamic stability, and improved fetal outcomes, but logistical and training challenges remain. Hybrid approaches combining hemodialysis and peritoneal dialysis may benefit select women during pregnancy. Effective management of pregnancy on dialysis requires treatment of anemia, optimized nutrition, close obstetric monitoring, and multi-disciplinary care. Postpartum care should focus on breastfeeding support, home dialysis prescription adjustment, and contraception counseling. Systematic capacity-building in home dialysis can lead to better pregnancy outcomes while alleviating in-center dialysis burdens.<\/jats:p>","DOI":"10.1177\/08968608251389274","type":"journal-article","created":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T15:51:13Z","timestamp":1761666673000},"page":"202-212","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Pregnancy in women on home dialysis: Your questions answered"],"prefix":"10.1177","volume":"46","author":[{"given":"Divya","family":"Bajpai","sequence":"first","affiliation":[{"name":"Seth G.S.M.C. and K.E.M. Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1116-2521","authenticated-orcid":false,"given":"Shreepriya","family":"Mangalgi","sequence":"additional","affiliation":[{"name":"University of Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prasoon","family":"Verma","sequence":"additional","affiliation":[{"name":"University of Cincinnati College of Medicine"},{"name":"Division of Neonatology, Cincinnati Children's Hospital Medical Center, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9941-9404","authenticated-orcid":false,"given":"Silvi","family":"Shah","sequence":"additional","affiliation":[{"name":"University of Cincinnati"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,10,28]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1542-4758.2009.00404.x"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.12601211"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(97)90120-7"},{"key":"e_1_3_2_5_2","doi-asserted-by":"crossref","unstructured":"Hewawasam E Davies CE Gulyani A et al. Factors influencing fertility rates in Australian women receiving kidney replacement therapy: analysis of linked Australia and New Zealand Dialysis and Transplant Registry and perinatal data over 22 years https:\/\/doi.org\/10.1093\/ndt\/gfab157 (accessed December 3 2024).","DOI":"10.1093\/ndt\/gfab157"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/nep.12044"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2019.08.029"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2019030234"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1797.2011.01520.x"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.04110907"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2013080825"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2024.01.045"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfv395"},{"key":"e_1_3_2_14_2","unstructured":"Lim CTS Wah FK. Pregnancy and peritoneal dialysis: an updated review. Published online July 12 2018 https:\/\/www.emjreviews.com\/nephrology\/article\/pregnancy-and-peritoneal-dialysis-an-updated-review\/ (accessed December 9 2024)."},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/ckj\/sfac204"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1159\/000488286"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2018.04.013"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41430-019-0550-6"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1980.tb04434.x"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2024.05.008"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.11604\/pamj-oh.2023.11.1.39297"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1159\/000044970"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.5414\/CNCS110828"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.3747\/pdi.2018.00054"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(99)70426-9"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1258\/om.2010.100001"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.03560413"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5000382"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5002600"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.3390\/toxins16070298"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2016.02.037"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2023.02.1077"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.semnephrol.2017.02.007"},{"key":"e_1_3_2_34_2","first-page":"3266","article-title":"Pregnancy during dialysis: case report and management guidelines","volume":"13","author":"Giatras I","year":"1998","unstructured":"Giatras I, Levy DP, Malone FD, et al. Pregnancy during dialysis: case report and management guidelines. Nephrol Dial Transplant Off Publ Eur Dial Transpl Assoc \u2013 Eur Ren Assoc 1998; 13: 3266\u20133272.","journal-title":"Nephrol Dial Transplant Off Publ Eur Dial Transpl Assoc \u2013 Eur Ren Assoc"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1002\/dat.20153"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.0000000000000437"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrneph.2012.145"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2009.48"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.05660809"},{"key":"e_1_3_2_40_2","first-page":"99","article-title":"Hemodialysis and pregnancy: technical aspects","volume":"78","author":"V\u00e1zquez-Rodr\u00edguez JG","year":"2010","unstructured":"V\u00e1zquez-Rodr\u00edguez JG. Hemodialysis and pregnancy: technical aspects. Cir Cir 2010; 78: 99\u2013102.","journal-title":"Cir Cir"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40620-022-01288-y"},{"key":"e_1_3_2_42_2","first-page":"140","article-title":"Successful pregnancy in an end-stage renal disease patient on peritoneal dialysis","volume":"28","author":"Inal S","year":"2012","unstructured":"Inal S, Reis KA, Arma\u011fan B, et al. Successful pregnancy in an end-stage renal disease patient on peritoneal dialysis. Adv Perit Dial Conf Perit Dial 2012; 28: 140\u2013141.","journal-title":"Adv Perit Dial Conf Perit Dial"},{"key":"e_1_3_2_43_2","unstructured":"Pregnancy in patients on chronic dialysis: a single center experience and combined analysis of reported results \u2013 PubMed https:\/\/pubmed.ncbi.nlm.nih.gov\/17560006\/ (accessed 26 December 2024)."},{"key":"e_1_3_2_44_2","unstructured":"Peritoneal dialysis in pregnancy: a case series \u2013 PubMed https:\/\/pubmed.ncbi.nlm.nih.gov\/18844832\/ (accessed December 26 2024)."},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.3747\/pdi.2013.00229"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40620-015-0191-3"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.ackd.2020.06.001"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.3747\/pdi.2016.00051"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12882-020-01729-5"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.8551"},{"key":"e_1_3_2_51_2","unstructured":"Circulating Angiogenic Factors in a Pregnant Woman on Intensive Hemodialysis: A Case Report\u2014Ayub Akbari Michelle Hladunewich Kevin Burns Felipe Moretti Rima Abou Arkoub Pierre Brown Swapnil Hiremath 2016 https:\/\/journals.sagepub.com\/doi\/10.1186\/s40697-016-0096-7 (accessed December 31 2024)."},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2008.03.011"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.1002\/pd.564"},{"key":"e_1_3_2_54_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2019.11.007"},{"key":"e_1_3_2_55_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12882-023-03264-5"},{"key":"e_1_3_2_56_2","doi-asserted-by":"publisher","DOI":"10.25259\/IJN_374_2024"},{"key":"e_1_3_2_57_2","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.07170713"},{"key":"e_1_3_2_58_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200101113440204"}],"container-title":["Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/08968608251389274","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/08968608251389274","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/08968608251389274","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T18:10:41Z","timestamp":1779041441000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/08968608251389274"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,28]]},"references-count":57,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1177\/08968608251389274"],"URL":"https:\/\/doi.org\/10.1177\/08968608251389274","relation":{},"ISSN":["0896-8608","1718-4304"],"issn-type":[{"value":"0896-8608","type":"print"},{"value":"1718-4304","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,28]]}}}