{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:41:03Z","timestamp":1777927263066,"version":"3.51.4"},"reference-count":7,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T00:00:00Z","timestamp":1771200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100011912","name":"Taipei Veterans General Hospital","doi-asserted-by":"publisher","award":["V114C-070"],"award-info":[{"award-number":["V114C-070"]}],"id":[{"id":"10.13039\/501100011912","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020950","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["112-2314-B-A49-059-MY3"],"award-info":[{"award-number":["112-2314-B-A49-059-MY3"]}],"id":[{"id":"10.13039\/501100020950","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020950","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["114-2314-B-A49-069-MY3"],"award-info":[{"award-number":["114-2314-B-A49-069-MY3"]}],"id":[{"id":"10.13039\/501100020950","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005382","name":"National Yang-Ming University","doi-asserted-by":"publisher","award":["113Q158505"],"award-info":[{"award-number":["113Q158505"]}],"id":[{"id":"10.13039\/501100005382","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005799","name":"National Chiao Tung University","doi-asserted-by":"publisher","award":["Center for Intelligent Drug Systems and Smart Bio-"],"award-info":[{"award-number":["Center for Intelligent Drug Systems and Smart Bio-"]}],"id":[{"id":"10.13039\/501100005799","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perit Dial Int"],"abstract":"<jats:p>Early identification of encapsulating peritoneal sclerosis (EPS) remains challenging, particularly in the absence of definitive radiological signs. We report a case of a 69-year-old male with end-stage kidney disease on peritoneal dialysis (PD) for 9 years, who developed poor appetite and weight loss. After complete drainage of ascites, PD was ceased for 1 day, during which 500\u2005mL of newly formed ascites accumulated. Ascitic interleukin-6 and CA-125 levels were markedly elevated, raising concern for evolving EPS. Although computed tomography showed bowel dilatation and focal peritoneal thickening without calcification or a fibrous cocoon, the ongoing production of fibrin-rich ascites and weight loss prompted a transition to hemodialysis (HD) and corticosteroid treatment. After transitioning to HD, the volume of weekly drained ascites decreased slowly, and his appetite and weight began to recover. This case highlights that rapidly accumulating ascites following a brief cessation of PD may serve as an early and clinically meaningful marker of EPS development, especially in high-risk individuals. Timely recognition of this subtle manifestation could enable earlier intervention and improve outcomes.<\/jats:p>","DOI":"10.1177\/08968608261424185","type":"journal-article","created":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T17:39:32Z","timestamp":1771263572000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Rapidly accumulating ascites as an early clue to encapsulating peritoneal sclerosis"],"prefix":"10.1177","author":[{"given":"Cheng-Ching","family":"Hsieh","sequence":"first","affiliation":[{"name":"National Yang Ming Chiao Tung University"},{"name":"Faculty of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chieh-Hsiang","family":"Chang","sequence":"additional","affiliation":[{"name":"Taipei Veterans General Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5003-3463","authenticated-orcid":false,"given":"David","family":"Law","sequence":"additional","affiliation":[{"name":"Peritoneal Dialysis Working Committee of the Taiwan Society of Nephrology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9899-3159","authenticated-orcid":false,"given":"Chih-Yu","family":"Yang","sequence":"additional","affiliation":[{"name":"National Yang Ming Chiao Tung University"},{"name":"Faculty of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei"},{"name":"Taipei Veterans General Hospital"},{"name":"Peritoneal Dialysis Working Committee of the Taiwan Society of Nephrology"},{"name":"Center for Intelligent Drug Systems and Smart Bio-devices (IDS2B), National Yang Ming Chiao Tung University, Hsinchu"},{"name":"Stem Cell Research Center, National Yang Ming Chiao Tung University, Taipei"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,2,16]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.3747\/pdi.2017.00018"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.semnephrol.2011.01.007"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1177\/089686080502504S05"},{"key":"e_1_3_2_5_2","first-page":"1","article-title":"Clinical risk factors and outcomes of massive ascites accumulation after discontinuation of peritoneal dialysis","volume":"42","author":"Chang MS","year":"2020","unstructured":"Chang MS, Chen NC, Hsu CY, et al. Clinical risk factors and outcomes of massive ascites accumulation after discontinuation of peritoneal dialysis. 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