{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T01:54:21Z","timestamp":1777859661671,"version":"3.51.4"},"reference-count":6,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2012,7,25]],"date-time":"2012-07-25T00:00:00Z","timestamp":1343174400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pharmacy Practice"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:p>Graves\u2019 disease is an autoimmune syndrome with symptoms such as tachycardia, atrial fibrillation, and psychiatric symptoms. Limited evidence exists for the treatment of Graves\u2019 hyperthyroidism-induced psychosis with atypical antipsychotics. A 47-year-old female with a psychiatric history of bipolar disorder presented for the first time to the psychiatric hospital. She was agitated and grossly psychotic with delusions. Electrocardiogram showed atrial fibrillation and tachycardia. Drug screen urinalysis was negative. Endocrine workup resulted in a diagnosis of Graves\u2019 disease (thyroid-stimulating hormone [TSH]: 0.005 \u03bcIU\/mL, triiodothyronine [T3]: 537 ng\/dL, thyroxine [T4]: 24 mcg\/dL, free T4: 4.5 ng\/dL, positive antithyroid peroxidase antibody, and antinuclear antibody). Aripiprazole 10 mg daily was initiated and titrated to 15 mg daily on day 4. On day 16, her suspicious behavior, judgment, and insight improved. Other medications given included aspirin 325 mg daily, metoprolol 25 mg twice daily, titrated to 12.5 mg twice daily, and methimazole 30 mg daily, titrated to 20 mg twice daily, and discontinued on day 29. The patient received radioiodine I-131 treatment 1 week later. We report the first known case on the use of aripriprazole to treat Graves\u2019 hyperthyroidism-induced psychosis. Further studies examining the long-term effects and appropriate dose and duration of aripiprazole in this patient population are needed.<\/jats:p>","DOI":"10.1177\/0897190012451934","type":"journal-article","created":{"date-parts":[[2012,7,27]],"date-time":"2012-07-27T09:31:41Z","timestamp":1343381501000},"page":"59-61","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Graves\u2019 Hyperthyroidism-Induced Psychosis Treated With Aripiprazole\u2014A Case Report"],"prefix":"10.1177","volume":"26","author":[{"given":"Livia R.","family":"Macedo","sequence":"first","affiliation":[{"name":"Department of Pharmacy Services, University of Mississippi Medical Center, MS, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jehan","family":"Marino","sequence":"additional","affiliation":[{"name":"Nova Southeastern University, College of Pharmacy, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brady","family":"Bradshaw","sequence":"additional","affiliation":[{"name":"University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Henry","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences, University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2012,7,25]]},"reference":[{"key":"bibr1-0897190012451934","doi-asserted-by":"publisher","DOI":"10.2165\/00023210-200620110-00003"},{"key":"bibr2-0897190012451934","doi-asserted-by":"publisher","DOI":"10.1016\/S1568-9972(03)00006-5"},{"key":"bibr3-0897190012451934","doi-asserted-by":"publisher","DOI":"10.4088\/PCC.v07n0610a"},{"key":"bibr4-0897190012451934","doi-asserted-by":"publisher","DOI":"10.1007\/s11739-009-0259-y"},{"issue":"1","key":"bibr5-0897190012451934","first-page":"60","volume":"37","author":"Kua EH.","year":"1982","journal-title":"Med J Malaysia"},{"key":"bibr6-0897190012451934","unstructured":"Geodon\n                      \u00ae\n                      Ziprasidone HCL [package insert]. New York, NY: Roerig Division of Pfizer Inc; 2010."}],"container-title":["Journal of Pharmacy Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0897190012451934","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0897190012451934","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0897190012451934","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:35:15Z","timestamp":1777509315000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0897190012451934"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7,25]]},"references-count":6,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["10.1177\/0897190012451934"],"URL":"https:\/\/doi.org\/10.1177\/0897190012451934","relation":{},"ISSN":["0897-1900","1531-1937"],"issn-type":[{"value":"0897-1900","type":"print"},{"value":"1531-1937","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,7,25]]}}}