{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T16:30:12Z","timestamp":1790613012768,"version":"4.1.0"},"reference-count":26,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2017,10,10]],"date-time":"2017-10-10T00:00:00Z","timestamp":1507593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pharmacy Practice"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Hospitals and other facilities utilize antibiograms as tools for optimal antibiotic selection. Currently, no measures compare broad trends on the regional level, despite interest for more comprehensive data, particularly for antibiotic-resistant ESKAPE organisms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To collect and compare regional health-care facility antibiogram data for ESKAPE organisms to form a cumulative antibiogram.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Health-care facilities were identified using the publicly accessible Pennsylvania Department of Health web site. Facilities were contacted by phone from June 2015 to 2016 to ascertain participation\/consent for the study. An electronic questionnaire ascertained baseline facility characteristics. Facilities provided quantitative antibiotic susceptibility data via antibiograms. Antibiogram data were synthesized as cumulative susceptibilities, stratified by urban\/suburban versus rural location.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Forty-five facilities were included in the study (n = 18 urban\/suburban, n = 27 rural). The overall prevalence of methicillin-resistant S aureus was 41.5%, stratified at 40.6% and 43.3% in urban\/suburban and rural facilities, respectively ( P &lt; .001). Vancomycin-resistant Enterococcus prevalence was 18.8% overall, with 27.7% in urban\/suburban and 14.0% in rural facilities ( P &lt; .001). Generally, lower susceptibility rates were found for high-utilization beta-lactams across gram-negative organisms in urban\/suburban facilities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Development of a regional cumulative antibiogram that targets key ESKAPE pathogens is feasible, while observed trends may help aid future antimicrobial stewardship efforts.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0897190017735425","type":"journal-article","created":{"date-parts":[[2017,10,10]],"date-time":"2017-10-10T21:36:47Z","timestamp":1507671407000},"page":"19-27","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Development of a Statewide Antibiogram to Assess Regional Trends in Antibiotic-Resistant ESKAPE Organisms"],"prefix":"10.1177","volume":"32","author":[{"given":"Anthony J.","family":"Guarascio","sequence":"first","affiliation":[{"name":"Division of Pharmacy Practice, Duquesne University School of Pharmacy, Pittsburgh, PA, USA"},{"name":"Allegheny General Hospital, Pittsburgh, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura M.","family":"Brickett","sequence":"additional","affiliation":[{"name":"Allegheny General Hospital, Pittsburgh, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy J.","family":"Porter","sequence":"additional","affiliation":[{"name":"Allegheny General Hospital, Pittsburgh, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy D.","family":"Lee","sequence":"additional","affiliation":[{"name":"Rite Aid Pharmacy, Gibsonia, PA, 15044"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin E.","family":"Gorse","sequence":"additional","affiliation":[{"name":"Rite Aid Pharmacy, Gibsonia, PA, 15044"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2913-2042","authenticated-orcid":false,"given":"Jordan R.","family":"Covvey","sequence":"additional","affiliation":[{"name":"Division of Pharmaceutical, Administrative and Social Sciences, Duquesne University School of Pharmacy, Pittsburgh, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,10,10]]},"reference":[{"key":"bibr1-0897190017735425","doi-asserted-by":"publisher","DOI":"10.1086\/533452"},{"key":"bibr2-0897190017735425","doi-asserted-by":"publisher","DOI":"10.1086\/595011"},{"key":"bibr3-0897190017735425","doi-asserted-by":"publisher","DOI":"10.1586\/eri.13.12"},{"key":"bibr4-0897190017735425","doi-asserted-by":"publisher","DOI":"10.1086\/510393"},{"key":"bibr5-0897190017735425","unstructured":"Centers for Disease Control and Prevention. Core elements of hospital antibiotic stewardship programs. 2014. http:\/\/www.cdc.gov\/getsmart\/healthcare\/implementation\/core-elements.html. Accessed March 15, 2017. Updated February 23, 2017."},{"key":"bibr6-0897190017735425","volume-title":"Analysis and Presentation of Cumulative Antimicrobial Susceptibility Test Data; Approved Guideline","author":"Clinical and Laboratory Standard Institute","year":"2014","edition":"4"},{"key":"bibr7-0897190017735425","doi-asserted-by":"publisher","DOI":"10.1016\/S0732-8893(96)00099-5"},{"key":"bibr8-0897190017735425","unstructured":"Food and Drug Administration. The National Antimicrobial Resistance Monitoring System. 2016. https:\/\/www.fda.gov\/AnimalVeterinary\/SafetyHealth\/AntimicrobialResistance\/NationalAntimicrobialResistanceMonitoringSystem\/. Accessed March 15, 2017. Updated November 18, 2016."},{"key":"bibr9-0897190017735425","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2009.08.020"},{"key":"bibr10-0897190017735425","unstructured":"JMI Labs. SENTRY Antimicrobial Surveillance Program. https:\/\/www.jmilabs.com\/sentry-surveillance-program\/. Accessed March 22, 2017."},{"issue":"3","key":"bibr11-0897190017735425","first-page":"S53","volume":"6","author":"Ginevan ME","year":"2002","journal-title":"Int J Infect Dis"},{"key":"bibr12-0897190017735425","doi-asserted-by":"publisher","DOI":"10.1086\/590063"},{"key":"bibr13-0897190017735425","doi-asserted-by":"publisher","DOI":"10.3201\/eid0902.020123"},{"key":"bibr14-0897190017735425","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.1.1-6.2004"},{"key":"bibr15-0897190017735425","unstructured":"Pennsylvania Department of Health. Healthcare facilities. http:\/\/sais.health.pa.gov\/commonpoc\/content\/publiccommonpoc\/normalSearch.asp. Accessed November 14, 2016."},{"key":"bibr16-0897190017735425","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00448-13"},{"key":"bibr17-0897190017735425","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.6.2629-2634.2005"},{"key":"bibr18-0897190017735425","doi-asserted-by":"publisher","DOI":"10.2146\/ajhp110332"},{"key":"bibr19-0897190017735425","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01077-15"},{"key":"bibr20-0897190017735425","unstructured":"Centers for Disease Control and Prevention. Active Bacterial Core Surveillance Report. Emerging Infections Program Network: methicillin-resistant\n                      Staphylococcus aureus\n                      . 2015. https:\/\/www.cdc.gov\/hai\/eip\/pdf\/2015-mrsa-annual-summary.pdf. Accessed March 15, 2017. Updated February 28, 2017."},{"key":"bibr21-0897190017735425","doi-asserted-by":"publisher","DOI":"10.1310\/hpj4804-295"},{"key":"bibr22-0897190017735425","doi-asserted-by":"publisher","DOI":"10.1086\/320186"},{"key":"bibr23-0897190017735425","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.45.6.1615-1620.2001"},{"key":"bibr24-0897190017735425","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw353"},{"key":"bibr25-0897190017735425","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/46.suppl_2.53"},{"key":"bibr26-0897190017735425","doi-asserted-by":"publisher","DOI":"10.3201\/eid1108.050135"}],"container-title":["Journal of Pharmacy Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0897190017735425","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0897190017735425","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0897190017735425","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:34:43Z","timestamp":1777509283000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0897190017735425"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,10]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["10.1177\/0897190017735425"],"URL":"https:\/\/doi.org\/10.1177\/0897190017735425","relation":{},"ISSN":["0897-1900","1531-1937"],"issn-type":[{"value":"0897-1900","type":"print"},{"value":"1531-1937","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,10]]}}}