{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T01:53:59Z","timestamp":1777859639538,"version":"3.51.4"},"reference-count":18,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2017,12,12]],"date-time":"2017-12-12T00:00:00Z","timestamp":1513036800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pharmacy Practice"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To evaluate the impact of a pharmacist-driven initiative to optimize aldosterone antagonist use in patients with heart failure with reduced ejection fraction (HFrEF) at a large community hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This single-center, retrospective cohort study compared patients with heart failure before and after the implementation of the initiative. Data for pre- and postinitiative patients were retrospectively collected to assess patient characteristics and aldosterone antagonist use. The primary outcome was a composite of eligible patients with heart failure discharged on aldosterone antagonist therapy or with a documented reason for ineligibility before and after commencement of pharmacist-driven aldosterone antagonist initiative.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The preinitiative cohort included 96 patients and the postinitiative cohort contained 92 patients. When the 3 month pre- and postinitiative groups were assessed, the primary outcome was noted in 60 (63%) of 96 patients in the preinitiative group and 87 (95%) of 92 patients in the postinitiative group ( P &lt; .0001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>In patients with HFrEF, a pharmacist-driven aldosterone antagonist optimization initiative significantly increased appropriate prescribing and documentation for aldosterone antagonist therapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0897190017747083","type":"journal-article","created":{"date-parts":[[2017,12,13]],"date-time":"2017-12-13T04:03:28Z","timestamp":1513137808000},"page":"158-162","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Evaluation of a Pharmacist-Driven Aldosterone Antagonist Stewardship Program in Patients With Heart Failure"],"prefix":"10.1177","volume":"32","author":[{"given":"Eric R.","family":"Sparks","sequence":"first","affiliation":[{"name":"New Hanover Regional Medical Center, Wilmington, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janna C.","family":"Beavers","sequence":"additional","affiliation":[{"name":"WakeMed Health and Hospitals, Raleigh, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,12,12]]},"reference":[{"key":"bibr1-0897190017747083","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2011.11.003"},{"key":"bibr2-0897190017747083","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2013.05.009"},{"key":"bibr3-0897190017747083","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra000050"},{"key":"bibr4-0897190017747083","doi-asserted-by":"publisher","DOI":"10.1592\/phco.2005.25.8.1126"},{"key":"bibr5-0897190017747083","doi-asserted-by":"publisher","DOI":"10.1006\/jmcc.2000.1129"},{"key":"bibr6-0897190017747083","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejheart.2004.04.013"},{"key":"bibr7-0897190017747083","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr170"},{"key":"bibr8-0897190017747083","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.05.019"},{"key":"bibr9-0897190017747083","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199909023411001"},{"key":"bibr10-0897190017747083","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1009492"},{"key":"bibr11-0897190017747083","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2010.06.052"},{"key":"bibr12-0897190017747083","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)01965-4"},{"key":"bibr13-0897190017747083","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa030207"},{"key":"bibr14-0897190017747083","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2013.03.007"},{"key":"bibr15-0897190017747083","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2010.08.036"},{"key":"bibr16-0897190017747083","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.116.002946"},{"key":"bibr17-0897190017747083","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.113.000709"},{"key":"bibr18-0897190017747083","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000509"}],"container-title":["Journal of Pharmacy Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0897190017747083","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0897190017747083","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0897190017747083","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:34:48Z","timestamp":1777509288000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0897190017747083"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,12]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,4]]}},"alternative-id":["10.1177\/0897190017747083"],"URL":"https:\/\/doi.org\/10.1177\/0897190017747083","relation":{},"ISSN":["0897-1900","1531-1937"],"issn-type":[{"value":"0897-1900","type":"print"},{"value":"1531-1937","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,12]]}}}