{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T01:54:47Z","timestamp":1777859687402,"version":"3.51.4"},"reference-count":31,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2019,6,30]],"date-time":"2019-06-30T00:00:00Z","timestamp":1561852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pharmacy Practice"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Medication errors account for nearly 250 000 deaths in the United States annually, with approximately 60% of errors occurring during transitions of care. Previous studies demonstrated that almost 80% of participants with human immunodeficiency virus (HIV) have experienced a medication error related to their antiretroviral therapy (ART).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>This retrospective chart review examines propensity and type of ART-related errors and further seeks to identify risk factors associated with higher error rates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Participants were identified as hospitalized adults \u226518 years old with preexisting HIV diagnosis receiving home ART from July 2015 to June 2017. Medication error categories included delays in therapy, dosing errors, scheduling conflicts, and miscellaneous errors. Logistic regression was used to examine risk factors for medication errors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Mean age was 49 years, 76.5% were men, and 72.1% used hospital-supplied medication. For the primary outcome, 60.3% (41\/68) of participants had at least 1 error, with 31.3% attributed to delays in therapy. Logistic regression demonstrated multiple tablet regimens (odds ratio [OR]: 3.40, 95% confidence interval [CI]: 1.22-9.48, P = .019) and serum creatinine (SCr) \u22651.5 mg\/dL (OR: 8.87, 95% CI: 1.07-73.45, P = .043) were predictive for risk of medication errors. Regimens with significant drug\u2013drug interactions (eg, cobicistat-containing regimens) were not significantly associated with increased risk of medication errors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Relevance:<\/jats:title>\n                    <jats:p>ART-related medication error rates remain prevalent and exceeded 60%. Independent risk factors for medication errors include use of multiple tablet regimens and SCr \u22651.5 mg\/dL.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0897190019857842","type":"journal-article","created":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:01:28Z","timestamp":1561939288000},"page":"103-109","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Accuracy of Antiretroviral Prescribing in a Community Teaching Hospital: A Medication Use Evaluation"],"prefix":"10.1177","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7059-3206","authenticated-orcid":false,"given":"Jacob","family":"Lines","sequence":"first","affiliation":[{"name":"Department of Pharmacy, Johnson City Medical Center, Johnson City, TN, USA"},{"name":"East Tennessee State University Physicians Infectious Diseases Clinic, Johnson City, TN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2626-7390","authenticated-orcid":false,"given":"Paul","family":"Lewis","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Johnson City Medical Center, Johnson City, TN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,6,30]]},"reference":[{"key":"bibr1-0897190019857842","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i2139"},{"key":"bibr2-0897190019857842","first-page":"27","volume":"8","author":"Rozich J","year":"2001","journal-title":"J Clin Outcomes Manag"},{"key":"bibr3-0897190019857842","doi-asserted-by":"publisher","DOI":"10.1136\/bmjoq-2017-000281"},{"key":"bibr4-0897190019857842","doi-asserted-by":"publisher","DOI":"10.1111\/ijcp.12701"},{"key":"bibr5-0897190019857842","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1R773"},{"key":"bibr6-0897190019857842","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkt323"},{"key":"bibr7-0897190019857842","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1K547"},{"issue":"8","key":"bibr8-0897190019857842","first-page":"587","volume":"46","author":"Osorio SN","year":"2014","journal-title":"Fam Med"},{"key":"bibr9-0897190019857842","doi-asserted-by":"publisher","DOI":"10.1186\/1758-2652-12-1"},{"key":"bibr10-0897190019857842","doi-asserted-by":"publisher","DOI":"10.2146\/ajhp070072"},{"key":"bibr11-0897190019857842","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1293.2011.00915.x"},{"key":"bibr12-0897190019857842","doi-asserted-by":"publisher","DOI":"10.2147\/PPA.S30244"},{"key":"bibr13-0897190019857842","doi-asserted-by":"publisher","DOI":"10.1086\/507538"},{"key":"bibr14-0897190019857842","doi-asserted-by":"publisher","DOI":"10.1310\/hpj4512-927"},{"key":"bibr15-0897190019857842","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1P599"},{"key":"bibr16-0897190019857842","doi-asserted-by":"publisher","DOI":"10.1086\/520653"},{"key":"bibr17-0897190019857842","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1293.2011.00977.x"},{"key":"bibr18-0897190019857842","doi-asserted-by":"publisher","DOI":"10.1086\/521168"},{"key":"bibr19-0897190019857842","doi-asserted-by":"publisher","DOI":"10.1345\/aph.19399"},{"key":"bibr20-0897190019857842","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis491"},{"key":"bibr21-0897190019857842","doi-asserted-by":"publisher","DOI":"10.1177\/0897190012468451"},{"key":"bibr22-0897190019857842","doi-asserted-by":"publisher","DOI":"10.2146\/ajhp110172"},{"key":"bibr23-0897190019857842","doi-asserted-by":"publisher","DOI":"10.1016\/j.medmal.2013.07.006"},{"key":"bibr24-0897190019857842","doi-asserted-by":"publisher","DOI":"10.1086\/522992"},{"key":"bibr25-0897190019857842","unstructured":"Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in adults and adolescents living with HIV. Department of Health and Human Services. 2018. Accessed September 21, 2017. http:\/\/aidsinfo.nih.gov\/contentfiles\/adultandadolescentgl.pdf"},{"key":"bibr26-0897190019857842","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(18)30021-3"},{"key":"bibr27-0897190019857842","doi-asserted-by":"publisher","DOI":"10.1080\/13543784.2018.1460357"},{"key":"bibr28-0897190019857842","doi-asserted-by":"publisher","DOI":"10.1177\/0885066618803871"},{"key":"bibr29-0897190019857842","unstructured":"DeJesus E, Cohen C, Elion R, et al. First report of raltegravir (RAL, MK-0518) use after virologic rebound on elvitegravir (EVT, GS 9137). Program and abstracts of the 4th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention; July 22-25, 2007; Sydney, Australia. 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