{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T01:54:46Z","timestamp":1777859686562,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2019,8,26]],"date-time":"2019-08-26T00:00:00Z","timestamp":1566777600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pharmacy Practice"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Epidemiology and risk factors for bacteremia in pediatric and adolescent patients have not been fully elucidated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>The purpose of this study was to identify primary causative agents of bacteremia in pediatric and adolescent patients and associated risk factors. We hypothesized that these would be different than those seen in adults.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods:<\/jats:title>\n                    <jats:p>This retrospective cohort, epidemiologic evaluation included patients admitted to a tertiary referral center from January 01, 2013, to December 31, 2015. Patients &lt;18 years old with a confirmed positive blood culture were included; the first positive culture per organism per patient was analyzed. The primary outcome was to determine the most frequent causative organisms of bacteremia; the secondary outcome was an evaluation of risk factors for acquiring staphylococcal bacteremia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 913 isolates were evaluated, including 92 unique organisms. The most frequently identified were Staphylococcus epidermidis (238\/913, 26.1%), followed by Staphylococcus aureus (136\/913, 14.9%). Methicillin resistance was observed in 60.3% of S aureus. Two hundred thirty-six patients were included in the risk factor analysis. Prematurity, previous antibiotics, and intubation\/ventilation were more likely associated with S epidermidis ( P &lt; .001, P &lt; .001, and P = .032, respectively). Patients with a recent or previous hospitalization and those with dermatitis\/eczema were statistically more likely to grow S aureus ( P &lt; .001, P = .029, respectively).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Although epidemiology of organisms associated with pediatric and adolescent bacteremia was similar to adults, risk factors were different than seen in that population. Further understanding of these risk factors may be helpful in developing preemptive infection control strategies in patients at risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0897190019868056","type":"journal-article","created":{"date-parts":[[2019,8,26]],"date-time":"2019-08-26T23:53:32Z","timestamp":1566863612000},"page":"360-364","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Epidemiology and Risk Factors for Bacteremia in Pediatric and Adolescent Patients"],"prefix":"10.1177","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8635-0137","authenticated-orcid":false,"given":"Kayla R.","family":"Stover","sequence":"first","affiliation":[{"name":"University of Mississippi School of Pharmacy, Jackson, MS, USA"},{"name":"Division of Infectious Diseases, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Austin","family":"Morrison","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Henry Ford Hospital, Detroit, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tia","family":"Collier","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Baylor University Medical Center, Dallas, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabeth","family":"Schneider","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Centura Health St. Anthony Hospital, Lakewood, CO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jamie L.","family":"Wagner","sequence":"additional","affiliation":[{"name":"University of Mississippi School of Pharmacy, Jackson, MS, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda C.","family":"Capino","sequence":"additional","affiliation":[{"name":"University of Mississippi School of Pharmacy, Jackson, MS, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katie E.","family":"Barber","sequence":"additional","affiliation":[{"name":"University of Mississippi School of Pharmacy, Jackson, MS, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,8,26]]},"reference":[{"key":"bibr1-0897190019868056","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200407-916OC"},{"key":"bibr2-0897190019868056","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2018.03.005"},{"key":"bibr3-0897190019868056","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2016.174"},{"key":"bibr4-0897190019868056","doi-asserted-by":"publisher","DOI":"10.1177\/1757177417720998"},{"key":"bibr5-0897190019868056","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2018.04.033"},{"issue":"3","key":"bibr6-0897190019868056","doi-asserted-by":"crossref","first-page":"221","DOI":"10.4067\/S0716-10182017000300003","volume":"34","author":"Ch\u00e1vez-Velarde TJ","year":"2017","journal-title":"Rev Chilena 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2013;54(4):205\u2013207."},{"key":"bibr14-0897190019868056","doi-asserted-by":"publisher","DOI":"10.1016\/0196-6553(87)90137-4"},{"key":"bibr15-0897190019868056","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcmed.2005.02.005"},{"key":"bibr16-0897190019868056","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(98)90013-6"},{"key":"bibr17-0897190019868056","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0b013e318289ff1e"}],"container-title":["Journal of Pharmacy 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