{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T01:54:50Z","timestamp":1789696490888,"version":"4.0.1"},"reference-count":22,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2020,9,29]],"date-time":"2020-09-29T00:00:00Z","timestamp":1601337600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pharmacy Practice"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>Gabapentin is an analog of gamma-aminobutyric acid (GABA), but its complete mechanism is not well understood. Common adverse effects from gabapentin include somnolence, sedation, and dizziness. Hyperglycemia is listed as a possible adverse drug reaction in the labeling. Case reports describe hypoglycemia in patients with diabetes, peritoneal dialysis, and\/or incomplete medication records. The following case report details a hypoglycemia episode as a potential result of a gabapentin use in a patient without diabetes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Summary:<\/jats:title>\n                    <jats:p>A 47-year old, 68 kg, white female presented to the emergency department with altered mental status. Her blood glucose level was 33 mg\/dL. Gabapentin was started 1 week prior to the hypoglycemia episode. Her past medical history, concomitant medications, and other laboratory findings were not likely causes of her severe hypoglycemia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      Gabapentin appears to have effects on several voltage-gated calcium channels. Hypoglycemia may be due to gabapentin binding to the alpha\n                      <jats:sub>2<\/jats:sub>\n                      delta subunit of the calcium channels in the pancreas. Future research should investigate gabapentin and the potential for hypoglycemia.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0897190020961229","type":"journal-article","created":{"date-parts":[[2020,9,29]],"date-time":"2020-09-29T05:46:54Z","timestamp":1601358414000},"page":"298-301","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Patient Case Report: Gabapentin-Induced Hypoglycemia"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4285-1490","authenticated-orcid":false,"given":"William J.","family":"Hayes","sequence":"first","affiliation":[{"name":"South Dakota State University, College of Pharmacy, Monument Health\u2014Flormann Clinic, Rapid City, SD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abigale","family":"Ferdinand","sequence":"additional","affiliation":[{"name":"Monument Health\u2014Rapid City Hospital, Rapid City, SD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Neabore","sequence":"additional","affiliation":[{"name":"Internal Medicine Physician, Monument Health\u2014Flormann Clinic, Rapid City, SD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Kappes","sequence":"additional","affiliation":[{"name":"South Dakota State University, College of Pharmacy, Monument Health\u2014Rapid City Hospital, Rapid City, SD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katie M.","family":"Hayes","sequence":"additional","affiliation":[{"name":"Monument Health\u2014Rapid City Hospital, Rapid City, SD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Berendse","sequence":"additional","affiliation":[{"name":"South Dakota State University, College of Pharmacy, VA Black Hills Health Care System, Fort Meade, SD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,9,29]]},"reference":[{"key":"bibr1-0897190020961229","volume-title":"Neurontin(R) Oral Capsules, Tablets, Solution, Gabapentin Oral Capsules, Tablets, Solution","author":"Product Information","year":"2010"},{"key":"bibr2-0897190020961229","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2003.08.033"},{"key":"bibr3-0897190020961229","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2017.05.010"},{"key":"bibr4-0897190020961229","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.12548"},{"key":"bibr5-0897190020961229","doi-asserted-by":"publisher","DOI":"10.2337\/dc20-S006"},{"key":"bibr6-0897190020961229","volume-title":"Ambien(R) Oral Tablets, Zolpidem Tartrate Oral Tablets. 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