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We report a unique case where a patient developed hyponatremia and upon rechallenge with aripiprazole resulted in a second incidence. There is limited literature recognizing aripiprazole induced SIADH and especially any focused on medication rechallenge.<\/jats:p>","DOI":"10.1177\/08971900251394100","type":"journal-article","created":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T23:30:17Z","timestamp":1761694217000},"page":"348-354","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Aripiprazole-Induced Hyponatremia Observed Upon Rechallenge: A Case Report"],"prefix":"10.1177","volume":"39","author":[{"given":"Nicholas","family":"McGuire","sequence":"first","affiliation":[{"name":"Pharmacy, Jesse Brown VA Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leslie","family":"Wu","sequence":"additional","affiliation":[{"name":"Pharmacy, Jesse Brown VA Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2317-5586","authenticated-orcid":false,"given":"Archana","family":"Jhawar","sequence":"additional","affiliation":[{"name":"Pharmacy, Jesse Brown VA Medical Center"},{"name":"University of Illinois Chicago"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,10,28]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2021.110654"},{"key":"e_1_3_3_3_2","volume-title":"Hyponatremia","author":"Rondon H","year":"2025","unstructured":"Rondon H, Badireddy M. 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