{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T23:41:38Z","timestamp":1781739698758,"version":"3.54.5"},"reference-count":17,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2020,9,27]],"date-time":"2020-09-27T00:00:00Z","timestamp":1601164800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Holist Nurs"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>This study examined nausea and vomiting (N\/V) in hospitalized patients following the use of inhaled peppermint essential oil (aromatherapy) compared to combined aromatherapy\/antiemetics or antiemetics alone.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method and Materials<\/jats:title>\n                    <jats:p>A total of 103 hospitalized patients were offered one of three options to control N\/V. Patient choice was considered in the holistic trial design so that patients were not denied either the essential oil or antiemetics. Patients rated nausea 0 to 10 on the Edmonton Symptom Assessment Scale at symptom onset and within 60 minutes of the intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Only three subjects enrolled in the antiemetic arm; thus this arm was eliminated from analysis, resulting in 100 evaluable patients. Mean nausea score improved significantly for the entire sample following the aromatherapy or aromatherapy\/antiemetic intervention ( p &lt; .0001). Patients in the aromatherapy arm had significant improvement in nausea compared to the combined aromatherapy\/antiemetic arm ( p &lt; .0001). Patient perception that peppermint oil relieves N\/V significantly improved for the entire sample. Notable is that 65% of patients used peppermint essential oil alone.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Peppermint essential oil is an effective independent or complementary modality for relief of N\/V in hospitalized patients. Research designs that incorporate patient decision making should be considered for studies in which placebos do not contribute to holistic care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0898010120961579","type":"journal-article","created":{"date-parts":[[2020,9,28]],"date-time":"2020-09-28T02:20:30Z","timestamp":1601259630000},"page":"126-134","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Peppermint Essential Oil for Nausea and Vomiting in Hospitalized Patients: Incorporating Holistic Patient Decision Making Into the Research Design"],"prefix":"10.1177","volume":"39","author":[{"given":"Carla","family":"Mohr","sequence":"first","affiliation":[{"name":"Billings Clinic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cassandra","family":"Jensen","sequence":"additional","affiliation":[{"name":"Billings Clinic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Padden","sequence":"additional","affiliation":[{"name":"Billings Clinic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamie M.","family":"Besel","sequence":"additional","affiliation":[{"name":"Billings Clinic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6654-739X","authenticated-orcid":false,"given":"Jeannine M.","family":"Brant","sequence":"additional","affiliation":[{"name":"Billings Clinic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,9,27]]},"reference":[{"key":"bibr1-0898010120961579","doi-asserted-by":"crossref","unstructured":"American Society of PeriAnesthesia Nurses PONV\/PDNV Strategic Work Team (2006). ASPAN\u2019S evidence-based clinical practice guideline for the prevention and\/or management of PONV\/PDNV. Journal of Perianesthesia Nursing, 21(4), 230-250. https:\/\/doi.org\/10.1016\/j.jopan.2006.06.003","DOI":"10.1016\/j.jopan.2006.06.003"},{"key":"bibr2-0898010120961579","doi-asserted-by":"crossref","unstructured":"Apfel C. C., Heidrich F. M., Jukar-Rao S., Jalota L., Hornuss C., Whelan R. P., Zhang K., Cakmakkaya O. S. (2012). Evidence-based analysis of risk factors for postoperative nausea and vomiting. British Journal of Anaesthesia, 109(5), 742-753. https:\/\/doi.org\/10.1093\/bja\/aes276","DOI":"10.1093\/bja\/aes276"},{"key":"bibr3-0898010120961579","doi-asserted-by":"crossref","unstructured":"Brant J. M., Beck S., Miaskowski C. (2010). Building dynamic models and theories to advance the science of symptom management research. 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