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Structural equation modeling was used to build a model describing relationships among physical and psychosocial secondary health conditions, pain, functional impairments, chronic medical conditions, and age. Results: In total, 12 individual symptom or function domains (latent factors) were identified, grouped into 5 broader factors. Increasing age was associated with greater rates of physical and health problems and poorer function, and showed curvilinear relationships with pain and psychosocial difficulties. Discussion: These data support a biopsychosocial model of secondary health conditions in adults aging with physical disability and suggest a five-factor approach for conceptualizing secondary conditions and their impact. Results also emphasize the importance of age in symptom severity and impact.<\/jats:p>","DOI":"10.1177\/0898264313516166","type":"journal-article","created":{"date-parts":[[2014,1,3]],"date-time":"2014-01-03T23:17:26Z","timestamp":1388791046000},"page":"335-359","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":49,"title":["Modeling Secondary Health Conditions in Adults Aging With Physical Disability"],"prefix":"10.1177","volume":"26","author":[{"given":"Ivan R.","family":"Molton","sequence":"first","affiliation":[{"name":"University of Washington Medical Center, Seattle, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra L.","family":"Terrill","sequence":"additional","affiliation":[{"name":"University of Washington Medical Center, Seattle, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda E.","family":"Smith","sequence":"additional","affiliation":[{"name":"University of Washington Medical Center, Seattle, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathryn M.","family":"Yorkston","sequence":"additional","affiliation":[{"name":"University of Washington Medical Center, Seattle, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin N.","family":"Alschuler","sequence":"additional","affiliation":[{"name":"University of Washington Medical Center, Seattle, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dawn M.","family":"Ehde","sequence":"additional","affiliation":[{"name":"University of Washington Medical Center, Seattle, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark P.","family":"Jensen","sequence":"additional","affiliation":[{"name":"University of Washington Medical Center, Seattle, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,1,3]]},"reference":[{"key":"bibr1-0898264313516166","doi-asserted-by":"publisher","DOI":"10.1038\/sc.2012.51sc201251"},{"key":"bibr2-0898264313516166","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2008.01.030"},{"key":"bibr3-0898264313516166","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2012.04.019S0003-9993(12)00315-2"},{"key":"bibr4-0898264313516166","volume-title":"Enabling America: Assessing the role of rehabilitation science and engineering","author":"Brandt E. 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