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A path model investigates the relationship between annual cost of care and dependence, cognitive ability, functioning, neuropsychiatric symptoms, and comorbidities. Results: Average annual cost among patients diagnosed with dementia was \u20ac43,259, primarily incurred by accommodation. Resource use, that is, institutional care, community care, and accommodation, and corresponding costs increased significantly by increasing dependency. Path analysis showed that cognitive ability, functioning, and neuropsychiatric symptoms were significantly correlated with dependence, which in turn had a strong impact on annual cost. Discussion: This study confirms that cost of dementia care increases with dependence and that the impact of other disease indicators is mainly mediated by dependence.<\/jats:p>","DOI":"10.1177\/0898264315624899","type":"journal-article","created":{"date-parts":[[2016,1,27]],"date-time":"2016-01-27T20:18:01Z","timestamp":1453925881000},"page":"1448-1464","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":37,"title":["Cost of Dementia and Its Correlation With Dependence"],"prefix":"10.1177","volume":"28","author":[{"given":"\u00d6rjan","family":"\u00c5kerborg","sequence":"first","affiliation":[{"name":"Optum (now Mapi), Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Lang","sequence":"additional","affiliation":[{"name":"Optum (now Mapi), Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders","family":"Wimo","sequence":"additional","affiliation":[{"name":"SNAC Nordanstig, Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders","family":"Sk\u00f6ldunger","sequence":"additional","affiliation":[{"name":"SNAC Nordanstig, Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Fratiglioni","sequence":"additional","affiliation":[{"name":"Karolinska Institutet-Stockholm University, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maren","family":"Gaudig","sequence":"additional","affiliation":[{"name":"Janssen Alzheimer Immunotherapy, Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mats","family":"Rosenlund","sequence":"additional","affiliation":[{"name":"Optum (now Mapi), Stockholm, Sweden"},{"name":"Karolinska Institutet, Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,7,9]]},"reference":[{"key":"bibr1-0898264315624899","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-1166(1998110)13:11<755::AID-GPS862>3.0.CO;2-Y"},{"key":"bibr2-0898264315624899","doi-asserted-by":"publisher","DOI":"10.1002\/gps.490"},{"key":"bibr3-0898264315624899","doi-asserted-by":"publisher","DOI":"10.1017\/S1041610210000785"},{"key":"bibr4-0898264315624899","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2004.52054.x"},{"key":"bibr5-0898264315624899","doi-asserted-by":"publisher","DOI":"10.2147\/CEOR.S81045"},{"key":"bibr6-0898264315624899","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2015.02.005"},{"key":"bibr7-0898264315624899","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.54.3.740"},{"key":"bibr8-0898264315624899","first-page":"528","volume":"34","author":"Fillit H.","year":"2002","journal-title":"Family Medicine"},{"key":"bibr9-0898264315624899","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1983.01790060110016"},{"key":"bibr10-0898264315624899","doi-asserted-by":"publisher","DOI":"10.1002\/gps.3819"},{"key":"bibr11-0898264315624899","volume-title":"Dependence in the elderly in New York City: Policy and service implications of the US-UK Cross-National Geriatric Community Study","author":"Gurland B.","year":"1978"},{"key":"bibr12-0898264315624899","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2010.09.001"},{"key":"bibr13-0898264315624899","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2011.08.008"},{"key":"bibr14-0898264315624899","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.58.1.62"},{"key":"bibr15-0898264315624899","doi-asserted-by":"publisher","DOI":"10.1016\/0168-8510(91)90095-F"},{"key":"bibr16-0898264315624899","doi-asserted-by":"publisher","DOI":"10.1002\/gps.1489"},{"key":"bibr17-0898264315624899","doi-asserted-by":"publisher","DOI":"10.1007\/BF03324546"},{"key":"bibr18-0898264315624899","doi-asserted-by":"publisher","DOI":"10.1002\/gps.3844"},{"key":"bibr19-0898264315624899","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2009.09.004"},{"key":"bibr20-0898264315624899","doi-asserted-by":"publisher","DOI":"10.2174\/156720510791162430"},{"key":"bibr21-0898264315624899","doi-asserted-by":"publisher","DOI":"10.1097\/WAD.0b013e31802f2426"},{"key":"bibr22-0898264315624899","unstructured":"Norrlands universitetssjukv\u00e5rd. 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